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  • The hemodynamic response to dexmedetomidine loading dose in children with and without pulmonary hypertension.
  • Friesen RH, Nichols CS, Twite MD, Cardwell KA, Pan Z, Pietra B, Miyamoto SD, Auerbach SR, Darst JR, Ivy DD.SourceDepartment of Anesthesiology, Children's Hospital Colorado, University of Colorado, 13123 E. 16th Ave., Aurora, CO 80045. robert.friesen@childrenscolorado.or.
  • Anesthesia and analgesia.Anesth Analg.2013 Oct;117(4):953-9. doi: 10.1213/ANE.0b013e3182a15aa6. Epub 2013 Aug 19.
  • BACKGROUND: Dexmedetomidine, an α-2 receptor agonist, is widely used in children with cardiac disease. Significant hemodynamic responses, including systemic and pulmonary vasoconstriction, have been reported after dexmedetomidine administration. Our primary goal of this prospective, observational s
  • PMID 23960035
  • Pain, agitation, delirium, and neuromuscular blockade: a review of basic pharmacology, assessment, and monitoring.
  • Altshuler J, Spoelhof B.SourceDepartment of Pharmacy, Memorial Hermann-Texas Medical Center, Houston, Texas.
  • Critical care nursing quarterly.Crit Care Nurs Q.2013 Oct-Dec;36(4):356-69. doi: 10.1097/CNQ.0b013e3182a10dbf.
  • Agitation, pain, and delirium are focal points for targeted pharmacologic therapy in the intensive care unit. Understanding how to treat these essential entities necessitates fundamental understanding of the pharmacology of sedation, analgesia, and antipsychotics. Monitoring the effectiveness of the
  • PMID 24002426
  • Suppression of phagosome proteolysis and Matrigel migration with the α2-adrenergic receptor agonist dexmedetomidine in murine dendritic cells.
  • Ueshima H, Inada T, Shingu K.SourceDepartment of Anesthesiology, Kansai Medical University , Osaka , Japan.
  • Immunopharmacology and immunotoxicology.Immunopharmacol Immunotoxicol.2013 Oct;35(5):558-66. doi: 10.3109/08923973.2013.822509. Epub 2013 Aug 8.
  • Abstract Dexmedetomidine is a highly-selective α2-adrenergic receptor agonist used for sedation of critically ill patients in an intensive care setting. Dendritic cells (DCs) in peripheral tissues sense certain foreign antigens and ingest and process them, while migrating to the regional lymph node
  • PMID 23927488


  • 気道管理にデクスメデトミジンとエアウェイスコープが有用であったコルネリア・デランゲ症候群患児の麻酔経験
  • 古屋 敦司,鈴木 翔,近藤 聡子 [他]
  • 麻酔 63(7), 810-813, 2014-07
  • NAID 40020146872
  • i-gelの意識下挿入を行った閉塞型睡眠時無呼吸症候群の麻酔経験
  • 松波 小百合,駒澤 伸泰,葛川 洋介 [他]
  • 麻酔 63(7), 807-809, 2014-07
  • NAID 40020146811
  • 自発呼吸温存下に左上葉のみで分離肺換気を施行した1症例
  • 北埜 学,駒澤 伸泰,大地 史広 [他]
  • 麻酔 63(7), 797-799, 2014-07
  • NAID 40020146692


Mechanisms of action Dexmedetomidine, an imidazole compound, is the pharmacologically active dextroisomer of medetomidine that displays specific and selective α 2-adrenoceptor agonism. The mechanism of action is ...
Welcome to the Dexmedetomidine Source, an interactive Internet site designed to provide information to physicians and healthcare personnel about dexmedetomidine hydrochloride injection (Precedex ), a novel ...


Dexmedetomidine was first introduced as dexdomitor dexmedetomidine provides Description Dexmedetomidine.svgDexmedetomidine Clinical UsesLet Me BuySedación con Dexmedetomidina en

拡張検索dexmedetomidine hydrochloride



塩酸デクスメデトミジン dexmedetomidine hydrochloride
プレセデックス Precedex
  • 選択性の高いα2刺激薬
  • 呼吸抑制を生じない静脈内鎮静薬
  • 作用:沈静、抗不安、軽度鎮痛、交感神経遮断作用
  • 作用持続時間:10分以内
  • 人工呼吸からウィーニングする際の鎮静に好適
  • 副作用:低血圧(30%)、徐脈(8%)。離脱後に興奮、交感神経系反跳現象のリスクがある → 24時間以上投与はやめること

dexmedetomidine hydrochloride」

  [★] 塩酸デクスメデトミジン