cytogenetic aberration

出典: meddic

abnormal karyotypechromosomal aberrationchromosomal abnormalitychromosome aberrationchromosome abnormalitycytogenetic abnormality

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  • Impact of unbalanced minor route versus major route karyotypes at diagnosis on prognosis of CML.
  • Fabarius A1, Kalmanti L2, Dietz CT2, Lauseker M3, Rinaldetti S2, Haferlach C4, Göhring G5, Schlegelberger B5, Jotterand M6, Hanfstein B2, Seifarth W2, Hänel M7, Köhne CH8, Lindemann HW9, Berdel WE10, Staib P11, Müller MC2, Proetel U2, Balleisen L12, Goebeler ME13, Dengler J14, Falge C15, Kanz L16, Burchert A17, Kneba M18, Stegelmann F19, Pfreundschuh M20, Waller CF21, Spiekermann K22, Brümmendorf TH23, Edinger M24, Hofmann WK2, Pfirrmann M3, Hasford J3, Krause S25, Hochhaus A26, Saußele S2, Hehlmann R2; SAKK and the German CML Study Group.
  • Annals of hematology.Ann Hematol.2015 Dec;94(12):2015-24. doi: 10.1007/s00277-015-2494-9. Epub 2015 Sep 18.
  • Major route additional cytogenetic aberrations (ACA) at diagnosis of chronic myeloid leukaemia (CML) indicate an increased risk of progression and shorter survival. Since major route ACA are almost always unbalanced, it is unclear whether other unbalanced ACA at diagnosis also confer an unfavourable
  • PMID 26385387
  • Chromosome aberrations detected by conventional karyotyping using novel mitogens in chronic lymphocytic leukemia: Clinical and biologic correlations.
  • Rigolin GM1, Del Giudice I2, Formigaro L1, Saccenti E1, Martinelli S1, Cavallari M1, Lista E1, Tammiso E1, Volta E1, Lupini L3, Bassi C3, Bardi A1, Sofritti O1, Daghia G1, Cavazzini F1, Marinelli M2, Tavolaro S2, Guarini A2, Negrini M3, Foà R2, Cuneo A1.
  • Genes, chromosomes & cancer.Genes Chromosomes Cancer.2015 Dec;54(12):818-26. doi: 10.1002/gcc.22293. Epub 2015 Sep 10.
  • To clarify whether karyotype aberrations (KA) involving regions not covered by the standard fluorescence in situ hybridization (FISH) panel have independent prognostic relevance, we evaluated KA by conventional cytogenetics in a learning cohort (LC; n = 166) and a validation cohort (VC; n = 
  • PMID 26355802
  • Frequency of del(12p) is commonly underestimated in myelodysplastic syndromes: Results from a German diagnostic study in comparison with an international control group.
  • Braulke F1, Müller-Thomas C2, Götze K2, Platzbecker U3, Germing U4, Hofmann WK5, Giagounidis AA6, Lübbert M7, Greenberg PL8, Bennett JM9, Solé F10, Slovak ML11, Ohyashiki K12, Le Beau MM13, Tüchler H14, Pfeilstöcker M15, Hildebrandt B16, Aul C17, Stauder R18, Valent P19, Fonatsch C20, Bacher U1, Trümper L1, Haase D1, Schanz J1.
  • Genes, chromosomes & cancer.Genes Chromosomes Cancer.2015 Dec;54(12):809-17. doi: 10.1002/gcc.22292. Epub 2015 Sep 10.
  • In myelodysplastic syndromes (MDS), deletion of the short arm of chromosome 12 (del(12p)) is usually a small abnormality, rarely detected as a single aberration by chromosome banding analysis (CBA) of bone marrow metaphases. Del(12p) has been described in 0.6 to 5% of MDS patients at initial diagnos
  • PMID 26355708


  • Olive (Olea europaea L.) leaf extract counteracts genotoxicity and oxidative stress of permethrin in human lymphocytes
  • TURKEZ Hasan,TOGAR Basak
  • Journal of toxicological sciences 36(5), 531-537, 2011-10-01
  • … Anti-genotoxic activities of OLE were studied using sister chromatid exchange (SCE) and chromosome aberration (CA) tests and furthermore total antioxidant capacity (TAC) and total oxidative status (TOS) were examined to determine the oxidative damage. … The combined treatment showed significant improvements in cytogenetic and biochemical parameters tested. …
  • NAID 10029481103
  • Evaluation of Radioprotective Effects of Propolis and Quercetin on Human White Blood Cells in Vitro(Biopharmacy)
  • Biological & pharmaceutical bulletin 31(9), 1778-1785, 2008-09-01
  • … The levels of primary DNA damage were studied by the alkaline comet assay, while the cytogenetic damage was evaluated using the analysis of structural chromosome aberration and cytokinesis-block micronucleus assay. … Propolis was found to be more effective in diminishing the levels of primary and more complex cytogenetic DNA damage in gamma-irradiated white blood cells. …
  • NAID 110006878968


chromosomal aberration [-sō′məl] Etymology: Gk, chroma + soma, body; L, aberrare, to wander any change in the structure or number of any of the chromosomes of a given species. In humans, a number of physical ...
Understanding chromosome aberrations through cytogenetic analysis is an integral part of current genomic medicine, playing a role in research into both constitutional disorders and cancer. At Illumina, we collaborate with industry ...


 Abnormalities; Cytogenetic Aberrations Abnormalities; Cytogenetic Aberrations Abnormalities; Cytogenetic Aberrations Abnormalities; Cytogenetic AberrationsTable (3) . Cytogenetic characteristic and  Cytogenetic Aberrations; Karyotype

リンク元chromosome aberration」「chromosomal aberration」「chromosomal abnormality」「chromosome abnormality」「cytogenetic abnormality

chromosome aberration」


abnormal karyotypechromosomal aberrationchromosomal abnormalitychromosomal anomalychromosomal disorderchromosome abnormalitycytogenetic aberrationcytogenetic abnormality

chromosomal aberration」


abnormal karyotypechromosomal abnormalitychromosomal anomalychromosomal disorderchromosome aberrationchromosome abnormalitycytogenetic aberrationcytogenetic abnormality

chromosomal abnormality」


abnormal karyotypechromosomal aberrationchromosomal anomalychromosomal disorderchromosome aberrationchromosome abnormalitycytogenetic aberrationcytogenetic abnormality

chromosome abnormality」


abnormal karyotypechromosomal aberrationchromosomal abnormalitychromosomal anomalychromosomal disorderchromosome aberrationcytogenetic aberrationcytogenetic abnormality

cytogenetic abnormality」


abnormal karyotypechromosomal aberrationchromosomal abnormalitychromosomal anomalychromosomal disorderchromosome aberrationchromosome abnormalitycytogenetic aberration



  • n.
  • 正道を外れること/常道を逸すること。逸脱。異常な性行為。(医)迷錯、精神異常。(生)異常型、かわりもの(sport)
aberrant, aberrantly, abnormal, abnormality, abnormally, anomalous, anomalously, anomaly, defect, departure, deviant, deviate, deviation, diverge, escape, extraordinarily, extraordinary, prolapse, unusual, unusually

WordNet   license wordnet

「an optical phenomenon resulting from the failure of a lens or mirror to produce a good image」
distortion, optical aberration

WordNet   license wordnet

「a disorder in one''s mental state」

PrepTutorEJDIC   license prepejdic

「正道からはずれること,非行,異常 / (軽い)精神異常」



  • adj.
  • 細胞遺伝学的な、細胞遺伝学の
cytogenetic finding 細胞遺伝学的所見

WordNet   license wordnet

「of or relating to cytogenetics」




WordNet   license wordnet

「the branch of biology that studies the cellular aspects of heredity (especially the chromosomes)」