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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/11/25 16:17:29」(JST)

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  • Hypertension in mice with transgenic activation of the brain renin-angiotensin system is vasopressin dependent.
  • Littlejohn NK, Siel RB Jr, Ketsawatsomkron P, Pelham CJ, Pearson NA, Hilzendeger AM, Buehrer BA, Weidemann BJ, Li H, Davis DR, Thompson AP, Liu X, Cassell MD, Sigmund CD, Grobe JL.SourceDept. of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, Univ. of Iowa, 51 Newton Rd., 2-307 BSB, Iowa City, IA 52242.
  • American journal of physiology. Regulatory, integrative and comparative physiology.Am J Physiol Regul Integr Comp Physiol.2013 May;304(10):R818-28. doi: 10.1152/ajpregu.00082.2013. Epub 2013 Mar 27.
  • An indispensable role for the brain renin-angiotensin system (RAS) has been documented in most experimental animal models of hypertension. To identify the specific efferent pathway activated by the brain RAS that mediates hypertension, we examined the hypothesis that elevated arginine vasopressin (A
  • PMID 23535460
  • Pharmacokinetics of intravenous conivaptan in subjects with hepatic or renal impairment.
  • Roy MJ, Erdman KA, Abeyratne AT, Plumb LC, Lasseter K, Riff DS, Keirns JJ.SourceAstellas Pharma Global Development, Inc., 1 Astellas Way, Northbrook, IL 60062, USA.
  • Clinical pharmacokinetics.Clin Pharmacokinet.2013 May;52(5):385-95. doi: 10.1007/s40262-013-0047-8.
  • BACKGROUND: Conivaptan is a non-peptide dual antagonist of vasopressin V1A and V2 receptors that is approved in the United States as an intravenous formulation for the treatment of euvolemic and hypervolemic hyponatremia in hospitalized patients. The pharmacokinetics of intravenous conivaptan had no
  • PMID 23456393
  • [Conivaptan inhibites cell proliferation and collagen production of cardiac fibroblasts induced by arginine vasopressin].
  • Xie Y, Sun Z, Gai L.SourceDepartment of Cardiology, General Hospital of PLA, Beijing 100853, China.
  • Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi.2013 May;29(5):477-80.
  • Objective To investigate the effects of arginine vasopressin (AVP) and its receptor antagonist conivaptan (CON) on the proliferation of cardiac fibroblasts (CFs) and the production of collagen I and III. Methods CFs were isolated by collagenase II method and purified with differential attachment and
  • PMID 23643265


  • Therapeutic Potential of Vasopressin-Receptor Antagonists in Heart Failure
  • New Topics in Vasopressin Receptors and Approach to Novel Drugs : Research and Development of Conivaptan Hydrochloride (YM087), a Drug for the Treatment of Hyponatremia
  • A Novel Vasopressin Dual V_<1A>/V_2 Receptor Antagonist, Conivaptan Hydrochloride, Improves Hyponatremia in Rats with Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH)(Pharmacology)


ConivaptanConivaptan hydrochlorideSkeletal formula of conivaptanhedtke80DistributionPremixed Pouch (Back)

拡張検索conivaptan hydrochloride



conivaptanconivaptan hydrochloride

conivaptan hydrochloride」