- 関
- Coagulopathy
WordNet
- bring disorder to (同)disarray
- a physical condition in which there is a disturbance of normal functioning; "the doctor prescribed some medicine for the disorder"; "everyone gets stomach upsets from time to time" (同)upset
- a disturbance of the peace or of public order
PrepTutorEJDIC
- 〈U〉『無秩序』,混乱,乱雑(confusion) / 《しばしば複数形で》(社会的・政治的な)粉争,騒動 / 〈C〉(肉体的・精神的な)不調,異常,障害 / …‘の'秩序を乱す / 〈心身〉‘に'異常を起こさせる
- 凝固,凝結
UpToDate Contents
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English Journal
- Vascular calcification: The price to pay for anticoagulation therapy with vitamin K-antagonists.
- Chatrou ML, Winckers K, Hackeng TM, Reutelingsperger CP, Schurgers LJ.AbstractVitamin K-antagonists (VKA) are the most widely used anti-thrombotic drugs with substantial efficacy in reducing risk of arterial and venous thrombosis. Several lines of evidence indicate, however, that VKA inhibit not only post-translational activation of vitamin K-dependent coagulation factors but also synthesis of functional extra-hepatic vitamin K-dependent proteins thereby eliciting undesired side-effects. Vascular calcification is one of the recently revealed side-effects of VKA. Vascular calcification is an actively regulated process involving vascular cells and a number of vitamin K-dependent proteins. Mechanistic understanding of vascular calcification is essential to improve VKA-based treatments of both thrombotic disorders and atherosclerosis. This review addresses vitamin K-cycle and vitamin K-dependent processes of vascular calcification that are affected by VKA. We conclude that there is a growing need for better understanding of the effects of anticoagulants on vascular calcification and atherosclerosis.
- Blood reviews.Blood Rev.2012 Jul;26(4):155-66. Epub 2012 Apr 18.
- Vitamin K-antagonists (VKA) are the most widely used anti-thrombotic drugs with substantial efficacy in reducing risk of arterial and venous thrombosis. Several lines of evidence indicate, however, that VKA inhibit not only post-translational activation of vitamin K-dependent coagulation factors but
- PMID 22520397
- Tribute: the American Society of Pediatric Hematology/Oncology (ASPHO) 2012 distinguished career award goes to Dr. Victor Blanchette.
- Zipursky A, Coppes MJ.SourceChildren's National Medical Center, Center for Cancer & Blood Disorders, Washington, DC 20010, USA.
- Pediatric blood & cancer.Pediatr Blood Cancer.2012 Jul 1;58(7):1011-3. doi: 10.1002/pbc.24130.
- PMID 22508571
Japanese Journal
- 症例報告 抗菌薬投与後に生じた無症候性後天性第Ⅴ因子インヒビター
- 抗菌薬投与後に生じた無症候性後天性第V因子インヒビター
- 金城 泰幸,吉村 和晃,鈴木 隆史,篠澤 圭子,仲宗根 啓,吉俣 哲志,西平 守樹,平安山 英達
- 臨床血液 55(11), 2311-2315, 2014
- 第V因子インヒビターは稀な疾患であり,発症の誘因や重症度が症例により大きく異なり,手術で使用するフィブリン糊が原因となることが多い。今回我々は,誤嚥性肺炎の治療目的で使用した抗菌薬によると思われた後天性第V因子インヒビターを経験した。症例は80歳代,男性。既往歴には心房細動,脳梗塞と腰部脊柱管狭窄を有する。誤嚥性肺炎の治療後に凝固能異常となり入院となった。凝固能検査ではPTとAPTTの異常な延長を …
- NAID 130004705981
- 先天性凝固因子欠損症(血友病,von Willebrand 病)の消化管出血と大腸内視鏡検査を契機に発見された凝固因子欠損症3例の検討
- 加藤 忠,緒方 完治
- 日本血栓止血学会誌 25(4), 504-511, 2014
- 要約:【目的】先天性凝固因子欠損症の消化管出血と大腸内視鏡検査時に偶然発見された先天性凝固因子欠損症の特徴を検討した.【方法】愛知三の丸病院に消化管出血で受診した凝固因子欠損症34 例81 回の出血源と,新規発見例3 例(血友病A,血友病B,von Willebrand 病各1 例)を検討した.【結果】出血源は上部消化管病変65 回,下部消化管病変8 回,内視鏡処置後8 回で,内視鏡診断した26 …
- NAID 130004687766
Related Pictures
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- 障害:個人的苦痛や機能の障害があるので「疾病」とは言えるものの、その背景にある臓器障害がもう一つはっきりしない場合に用いられる。(PSY.9)
- an untidy state; a lack of order or organization (⇔order)
- violent behaviour of large groups of people
- an illness that cause a part of the body to stop functioning correctly
- disease <> illness <> disorder
- 乱す、乱雑にする。(人)の(心身の)調子を狂わせる。