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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/10/01 16:42:40」(JST)

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  • History of chemotherapy of leprosy.
  • Noordeen SK1.
  • Clinics in dermatology.Clin Dermatol.2016 Jan-Feb;34(1):32-6. doi: 10.1016/j.clindermatol.2015.10.016. Epub 2015 Oct 28.
  • Chemotherapy of leprosy over the past 70 years has passed through several phases, from sulfones, to clofazimine, and to highly bactericidal drugs like rifampicin. The use particularly of the more potent drugs in effective combinations and the development of standard multidrug therapy regimens have m
  • PMID 26773621
  • Efflux pump inhibitors: targeting mycobacterial efflux systems to enhance TB therapy.
  • Pule CM1, Sampson SL2, Warren RM1, Black PA1, van Helden PD1, Victor TC1, Louw GE1.
  • The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2016 Jan;71(1):17-26. doi: 10.1093/jac/dkv316. Epub 2015 Oct 15.
  • The emergence of drug resistance continues to plague TB control, with a global increase in the prevalence of MDR-TB. This acts as a gateway to XDR-TB and thus emphasizes the urgency for drug development and optimal treatment options. Bedaquiline is the first new anti-TB drug approved by the FDA in 4
  • PMID 26472768
  • Inhibitory potential of tuberculosis drugs on ATP-binding cassette drug transporters.
  • Te Brake LH1, Russel FG2, van den Heuvel JJ3, de Knegt GJ4, de Steenwinkel JE5, Burger DM6, Aarnoutse RE7, Koenderink JB8.
  • Tuberculosis (Edinburgh, Scotland).Tuberculosis (Edinb).2016 Jan;96:150-7. doi: 10.1016/ Epub 2015 Oct 9.
  • BACKGROUND: Multiple-drug therapy for tuberculosis (TB) and TB-associated co-morbidity increase the likelihood of drug-drug interactions (DDIs). Inhibition of membrane transporters is an important mechanism underlying DDIs. In this study, we assessed the in vitro inhibitory potential of currently u
  • PMID 26682943


  • Inhibitory Potential of Twenty Five Anti-tuberculosis Drugs on CYP Activities in Human Liver Microsomes
  • Inhibitory Potential of Twenty Five Anti-Tuberculosis Drugs on CYP Activities in Human Liver Microsomes
  • オフロキサシン多剤併用療法の長期追跡による臨床評価
  • 日本ハンセン病学会雑誌 = Japanese journal of leprosy 76(3), 207-218, 2007-09-01
  • NAID 10019511477


化学療法剤ランプレンカプセル (製薬会社:サンド株式会社)細菌のDNAに結合し、またマクロファージのライソゾーム酵素を活性化することによりハンセン病の原因菌の増殖を抑え、ハンセン病による炎症を軽くします。 通常 ...
Detailed drug Information for clofazimine. Includes common brand names, drug descriptions, warnings, side effects and dosing information. ... Breast Feeding There are no adequate studies in women for determining infant risk when ...


clofazimine mdr tb 20 jan 2015 clofazimine  antileprosy and anti-inflammatory activityClofazimine (Cfz)Novartis Veterinary Atopica Capsules For clofazimineClofazimine is a fat-soluble