WordNet

being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
of long duration; "chronic money problems" (同)continuing
habitual; "a chronic smoker" (同)inveterate
a disorder characterized by an abnormal increase in the number of red blood cells in the blood

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1. 赤血球増加症患者に対する診断的アプローチ diagnostic approach to the patient with polycythemia
2. 真性多血症の臨床症状および診断 clinical manifestations and diagnosis of polycythemia vera
3. 真性多血症の予後および治療 prognosis and treatment of polycythemia vera
4. 先天性赤血球増多症および真性多血症の分子学的病因 molecular pathogenesis of congenital polycythemic disorders and polycythemia vera
5. 腎移植後の赤血球増多症 erythrocytosis following renal transplantation

Reversible bone marrow aplasia induced by pegylated interferon-α-2a therapy in a patient with primary myelofibrosis.

Mainali NR1, Bhatt VR2, Kedia S3, Krishnamurthy J2, Wake LM4, Akhtari M5.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.J Oncol Pharm Pract.2014 Oct;20(5):386-92. doi: 10.1177/1078155213504444. Epub 2013 Sep 24.
Interferon has been widely used in the management of patients with hematological malignancies such as polycythemia vera, myelofibrosis, chronic myeloid leukemia and viral infections such as chronic hepatitis C. Hematological adverse effects such as cytopenias have been observed, particularly in pati
PMID 24067929

Paraneoplastic Itch: An Expert Position Statement of the Special Interest Group (SIG) of the International Forum on the Study of Itch (IFSI).

Weisshaar E1, Weiss M, Mettang T, Yosipovitch G, Zylicz Z.
Acta dermato-venereologica.Acta Derm Venereol.2014 Sep 2. doi: 10.2340/00015555-1959. [Epub ahead of print]
In clinical practice, the term "paraneoplastic itch" is used to describe itch in patients with cancer. Patients with hematological or solid tumor malignancies can be affected. In general, paraneoplastic itch is considered a rare disorder. However, paraneoplastic itch in hematological malignancies su
PMID 25179683

Circulating YKL-40 in myelofibrosis a potential novel biomarker of disease activity and the inflammatory state.

Bjørn ME1, Andersen CL, Jensen MK, Hasselbalch HC.
European journal of haematology.Eur J Haematol.2014 Sep;93(3):224-8. doi: 10.1111/ejh.12332. Epub 2014 Apr 25.
Chronic myeloproliferative neoplasms (MPN), encompassing essential thrombocythaemia (ET), polycythaemia vera (PV) and myelofibrosis (PMF), are featured by a chronic inflammatory state which is pronounced in myelofibrosis The value of YKL-40 as a biomarker of disease burden has been demonstrated in s
PMID 24689875

A Case of Myeloid Sarcoma with Correlation to JAK2V617F Mutation, Complicated by Myelofibrosis and Secondary Acute Myeloid Leukemia

Yoshiki Yumiko,Asai Takashi,Ichikawa Motoshi,Hangaishi Akira,Ota Satoshi,Imai Yoichi,Takahashi Tsuyoshi,Kurokawa Mineo
Internal Medicine 50(21), 2649-2652, 2011
… The activating mutation of JAK2, V617F, has been found as a frequent mutation in myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), essential thrombocytosis (ET), and primary myelofibrosis (PMF). … This mutation is observed not only in MPNs, but also in chronic myelomonocytic leukemia, myelodysplastic syndrome and acute myeloid leukemia (AML). …
NAID 130001288629

Differences in the JAK2 and MPL Mutation Status in the Cell Lineages of the bcr/abl-negative Chronic Myeloproliferative Neoplasm Subtypes

Toyama Kohtaro,Karasawa Masamitsu,Yokohama Akihiko,Mitsui Takeki,Uchiumi Hideki,Saitoh Takayuki,Handa Hiroshi,Murakami Hirokazu,Nojima Yoshihisa,Tsukamoto Norifumi
Internal Medicine 50(21), 2557-2561, 2011
… Objective While the somatic mutation of Janus Kinase 2 (JAK2) and the thrombopoietin receptor (c-MPL) gene are thought to affect the pathogenesis of bcr/abl negative chronic myeloproliferative neoplasm (MPN), the relationship between the mutation and the clinical features remain obscure. … Results The JAK2-V617F mutation was observed in three lineages of granulocytes, platelets, and BFU-E in almost all polycythemia vera (PV) and primary myelofibrosis (PMF) patients. …
NAID 130001288611