関: desmoplastic medulloblastoma、medulloblastoma、medullomyoblastoma

WordNet

the state of a child between infancy and adolescence (同)puerility
the time of persons life when they are a child

PrepTutorEJDIC

『幼時』,子供時代

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1. 髄芽腫の治療および予後treatment and prognosis of medulloblastoma [show details]
…memory in survivors of childhood medulloblastoma, particularly in young patients and those with high-risk disease . Neuropsychological examinations are recommended in all medulloblastoma survivors to assist …
2. 髄芽腫の臨床症状、診断、およびリスク層別化clinical presentation diagnosis and risk stratification of medulloblastoma [show details]
…separately. Approximately 500 children are diagnosed with a medulloblastoma each year in the United States . Medulloblastoma is the most common malignant brain tumor of childhood, accounting for approximately …
3. 髄芽腫の組織病理的特徴、遺伝学的特徴、分子的サブグループhistopathology genetics and molecular subgroups of medulloblastoma [show details]
… Medulloblastomas are the most common malignant brain tumor of childhood and occur exclusively in the cerebellum. Histologically, they are highly cellular tumors with dark staining, round or oval nuclei …
4. 小児における中枢神経系腫瘍の疫学epidemiology of central nervous system tumors in children [show details]
… most common childhood malignancies, after hematologic malignancies, and are the most common pediatric solid organ tumor . Although progress has been made in the treatment of childhood tumors,… 100,000 person-years) include medulloblastoma (the predominant tumor of this group ),…
5. 小児における中枢神経系腫瘍のマネージメントに関する概要overview of the management of central nervous system tumors in children [show details]
…clinical settings: Older children with embryonal tumors (eg, medulloblastomas, high-grade astrocytomas) in combination with surgery and radiation therapy. Young children and infants with embryonal tumors …

English Journal

The calcium-sensing receptor and integrins modulate cerebellar granule cell precursor differentiation and migration.

Tharmalingam S1, Wu C1, Hampson DR1,2.
Developmental neurobiology.Dev Neurobiol.2016 Apr;76(4):375-89. doi: 10.1002/dneu.22321. Epub 2015 Jul 16.
In the developing cerebellum granule cell precursors (GCPs) proliferate in the external granule cell layer before differentiating and migrating to the inner granule cell layer. Aberrant GCP proliferation leads to medulloblastoma, the most prevalent form of childhood brain cancer. Here, we demonstrat
PMID 26138678

Dramatic response to temozolomide, irinotecan, and bevacizumab for recurrent medulloblastoma with widespread osseous metastases.

Bonney PA1, Santucci JA1, Maurer AJ1, Sughrue ME2, McNall-Knapp RY3, Battiste JD4.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.J Clin Neurosci.2016 Apr;26:161-3. doi: 10.1016/j.jocn.2015.10.022. Epub 2016 Jan 14.
There is little evidence to guide the choice of chemotherapeutic agents for osseous metastases in medulloblastoma. Recently, triple therapy with temozolomide, irinotecan, and bevacizumab has been reported to have efficacy in recurrent medulloblastoma, and this regimen alone and in combination with o
PMID 26777082

Metastatic Group 3 Medulloblastoma in a Patient With Tuberous Sclerosis Complex: Case Description and Molecular Characterization of the Tumor.

Moavero R1,2, Folgiero V3, Carai A4, Miele E5,6, Ferretti E5, Po A5, Diomedi Camassei F7, Lepri FR8, Vigevano F1, Curatolo P2, Valeriani M1, Colafati GS9, Locatelli F3,10, Tornesello A11, Mastronuzzi A3.
Pediatric blood & cancer.Pediatr Blood Cancer.2016 Apr;63(4):719-22. doi: 10.1002/pbc.25851. Epub 2015 Dec 2.
Medulloblastoma is the most common pediatric brain tumor. We describe a child with tuberous sclerosis complex that developed a Group 3, myc overexpressed, metastatic medulloblastoma (MB). Considering the high risk of treatment-induced malignancies, a tailored therapy, omitting radiation, was given.
PMID 26626406

Japanese Journal

小児悪性脳腫瘍の集学的治療

長嶋達也,河村淳史,山元一樹,長嶋宏明
脳神経外科ジャーナル 23(5), 409-417, 2014
小児脳腫瘍は白血病に次いで第2位の小児がんであり, 小児期の悪性新生物による死亡の主たる原因となっている. 治療の原則は, 正しい診断, 疾患の病期診断と予後予測, 集学的治療, 晩期障害の予防である. 手術, 化学療法, 放射線治療からなる集学的治療を超えて, 専門施設, 晩期障害への対処, 緩和医療, 家族サポート, キャリーオーバーへの取り組みなど包括的な医療システムを必要とするため, 小 …
NAID 130004610374

髄芽腫臨床を理解するための12項目(<特集>小児神経外科治療と長期予後)

杉山一彦,山崎文之,梶原佳則,渡辺陽祐,高安武志,栗栖薫
脳神経外科ジャーナル 20(5), 363-371, 2011-05-20
… 50日継続し,改善後も構語障害が残存する.病理分類はclassic medulloblastoma,desmoplastic/nodular medulloblastoma,medulloblastoma with extensive nodularity,large cell/anaplastic medulloblastomaの4型であり,いずれもWHO grade IVである.術後に年齢,残存腫瘍の多寡,播種の程度によりaverage-risk group,high-risk group,baby-medulloblastomaの3群に分類される.Average-risk groupは低線量の全脳・全脊髄 …
NAID 110008608119

Risk of primary childhood brain tumors related to season of birth in Kumamoto Prefecture, Japan

Makino Keishi,Nakamura Hideo,Hide Taku-ichiro,Kuratsu Jun-ichi,マキノケイシ,ナカムラヒデオ,ヒデタクイチロウ,クラツジュンイチ,牧野敬史,中村英夫,秀拓一郎,倉津純一
Child's Nervous System 27(1), 75-78, 2011-01
… Objective: Environmental factors present around the time of birth may induce the development of childhood cancer. … No statistically significant seasonal patterns were detected in the birth season of patients with astrocytoma, malignant glioma, and medulloblastoma. …
NAID 120003913473