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WordNet
- antibiotic related to cephalosporin but no longer in common use (同)Kafocin
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/02/07 20:12:31」(JST)
[Wiki en表示]
Cefaloglycin
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Systematic (IUPAC) name |
(6R,7R)-3-[(acetyloxy)methyl]-7-{[(2R)-2-amino-2-phenylacetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
Clinical data |
Pregnancy cat. |
? |
Legal status |
? |
Identifiers |
CAS number |
3577-01-3 Y |
ATC code |
None |
PubChem |
CID 19150 |
DrugBank |
DB00689 |
ChemSpider |
18069 Y |
UNII |
HD2D469W6U Y |
KEGG |
D01949 Y |
ChEBI |
CHEBI:34613 Y |
ChEMBL |
CHEMBL1200971 N |
Chemical data |
Formula |
C18H19N3O6S |
Mol. mass |
405.426 g/mol |
SMILES
- O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccccc3)N)COC(=O)C)C(=O)O
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InChI
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InChI=1S/C18H19N3O6S/c1-9(22)27-7-11-8-28-17-13(16(24)21(17)14(11)18(25)26)20-15(23)12(19)10-5-3-2-4-6-10/h2-6,12-13,17H,7-8,19H2,1H3,(H,20,23)(H,25,26)/t12-,13-,17-/m1/s1 Y
Key:FUBBGQLTSCSAON-PBFPGSCMSA-N Y
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N (what is this?) (verify)
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Cefaloglycin INN (also spelled cephaloglycin) is a first-generation cephalosporin antibiotic.
External links
- Tune B, Hsu C (1990). "The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and imipenem.". J Am Soc Nephrol 1 (5): 815–21. PMID 2133431.
- Tune B, Fravert D, Hsu C (1989). "Oxidative and mitochondrial toxic effects of cephalosporin antibiotics in the kidney. A comparative study of cephaloridine and cephaloglycin.". Biochem Pharmacol 38 (5): 795–802. doi:10.1016/0006-2952(89)90233-5. PMID 2930580.
Antibacterials: cell envelope antibiotics (J01C-J01D)
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Intracellular |
- inhibit peptidoglycan subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
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Glycopeptide |
- inhibit PG chain elongation: Vancomycin# (Oritavancin
- Telavancin)
- Teicoplanin (Dalbavancin)
- Ramoplanin
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β-lactams/
(inhibit PBP
cross-links) |
Penicillins
(penams)
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Extended sp.
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- aminopenicillins: Amoxicillin#
- Ampicillin# (Pivampicillin
- Hetacillin
- Bacampicillin
- Metampicillin
- Talampicillin)
- Epicillin
- carboxypenicillins: Carbenicillin (Carindacillin)
- Ticarcillin
- Temocillin
- ureidopenicillins: Azlocillin
- Piperacillin
- Mezlocillin
- other: Mecillinam (Pivmecillinam)
- Sulbenicillin
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Narrow sp.
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β-lactamase sensitive
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- Benzylpenicillin (G)#: Clometocillin
- Benzathine benzylpenicillin#
- Procaine benzylpenicillin#
- Azidocillin
- Penamecillin
- Phenoxymethylpenicillin (V)#: Propicillin
- Benzathine phenoxymethylpenicillin
- Pheneticillin
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β-lactamase resistant
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- Cloxacillin# (Dicloxacillin
- Flucloxacillin)
- Oxacillin
- Meticillin
- Nafcillin
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Penems
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Carbapenems
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- Biapenem
- Ertapenem
- antipseudomonal (Doripenem
- Imipenem
- Meropenem)
- Panipenem
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Cephalosporins/Cephamycins
(cephems)
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1st (PEcK)
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- Cefazolin#
- Cefacetrile
- Cefadroxil
- Cefalexin
- Cefaloglycin
- Cefalonium
- Cefaloridine
- Cefalotin
- Cefapirin
- Cefatrizine
- Cefazedone
- Cefazaflur
- Cefradine
- Cefroxadine
- Ceftezole
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2nd (HEN)
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- Cefaclor
- Cefamandole
- Cefminox
- Cefonicid
- Ceforanide
- Cefotiam
- Cefprozil
- Cefbuperazone
- Cefuroxime
- Cefuzonam
- cephamycin (Cefoxitin
- Cefotetan
- Cefmetazole)
- carbacephem (Loracarbef)
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3rd
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- Cefixime#
- Ceftriaxone#
- antipseudomonal (Ceftazidime#
- Cefoperazone)
- Cefcapene
- Cefdaloxime
- Cefdinir
- Cefditoren
- Cefetamet
- Cefmenoxime
- Cefodizime
- Cefotaxime
- Cefpimizole
- Cefpiramide
- Cefpodoxime
- Cefsulodin
- Cefteram
- Ceftibuten
- Ceftiolene
- Ceftizoxime
- oxacephem (Flomoxef
- Latamoxef ‡)
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4th (antips-)
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- Cefepime
- Cefozopran
- Cefpirome
- Cefquinome
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5th
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- Ceftobiprole
- Ceftaroline fosamil
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Veterinary
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- Ceftiofur
- Cefquinome
- Cefovecin
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Monobactams
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- Aztreonam
- Tigemonam
- Carumonam
- Nocardicin A
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β-lactamase inh.
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- penam (Sulbactam
- Tazobactam)
- clavam (Clavulanic acid)
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Combinations
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- Amoxicillin/clavulanic acid#
- Imipenem/cilastatin#
- Ampicillin/flucloxacillin
- Ampicillin/sulbactam (Sultamicillin)
- Piperacillin/tazobactam
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Other |
- polymyxins/detergent (Colistin
- Polymyxin B)
- depolarizing (Daptomycin)
- hydrolyze NAM-NAG (Lysozyme)
- Gramicidin
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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gr+f/gr+a (t)/gr-p (c)/gr-o
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drug (J1p, w, n, m, vacc)
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English Journal
- Ionization constants and solubility of compounds involved in enzymatic synthesis of aminopenicillins and aminocephalosporins.
- Kurochkina VB, Sklyarenko AV, Satarova JE, Yarotsky SV.SourceState Research Institute of Genetics and Selection of Industrial Microorganisms (GosNIIgenetika), 1st Dorozhny proezd, 1, Moscow, 117545, Russia.
- Bioprocess and biosystems engineering.Bioprocess Biosyst Eng.2011 Nov;34(9):1103-17. doi: 10.1007/s00449-011-0560-9. Epub 2011 Jun 23.
- The article deals with experimental determination of ionization constants and solubility for the compounds (target products, initial β-lactams, acylating agents and by-products) involved in enzymatic synthesis of some therapeutically used aminopenicillins and aminocephalosporins, namely ampicillin,
- PMID 21698348
- Determination of cephalosporins in solid binary mixtures by polarized IR- and Raman spectroscopy.
- Koleva BB, Kolev TM, Spiteller M.SourceUniversity of Sofia St. Kl. Ohridsky, Department of Analytical Chemistry, 1 J. Bourchier Boulevard, Sofia 1164, Bulgaria. BKoleva@chem.uni-sofia.bg
- Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2008 Sep 10;48(1):201-4. doi: 10.1016/j.jpba.2008.04.026. Epub 2008 May 4.
- Quantitative IR- and Raman spectroscopic determinations of four cephalosporin antibiotics in six solid binary mixtures have been conducted. This is a new approach for spectroscopic determination of these antibiotics, since the corresponding quantitative analysis in solution only has been reported so
- PMID 18602240
Japanese Journal
Related Links
- Cefaloglycin INN (also spelled cephaloglycin) is a first generation cephalosporin antibiotic. External links Tune B, Hsu C (1990). "The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and ...
- This editable Main Article is under development and not meant to be cited; by editing it you can help to improve it towards a future approved, citable version. ... Cefaloglycin, also called cephaloglycin, is a first-generation cephalosporin type of ...
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セファログリシン
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- cefaloglycin
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- 英
- cephaloglycin、cefaloglycin