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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/15 01:13:53」(JST)

Cefaloglycin INN (also spelled cephaloglycin) is a first-generation cephalosporin antibiotic.

Tune B, Hsu C (1990). "The renal mitochondrial toxicity of beta-lactam antibiotics: in vitro effects of cephaloglycin and imipenem.". J Am Soc Nephrol 1 (5): 815–21. PMID 2133431.
Tune B, Fravert D, Hsu C (1989). "Oxidative and mitochondrial toxic effects of cephalosporin antibiotics in the kidney. A comparative study of cephaloridine and cephaloglycin.". Biochem Pharmacol 38 (5): 795–802. doi:10.1016/0006-2952(89)90233-5. PMID 2930580.

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Ionization constants and solubility of compounds involved in enzymatic synthesis of aminopenicillins and aminocephalosporins.

Kurochkina VB1, Sklyarenko AV, Satarova JE, Yarotsky SV.
Bioprocess and biosystems engineering.Bioprocess Biosyst Eng.2011 Nov;34(9):1103-17. doi: 10.1007/s00449-011-0560-9. Epub 2011 Jun 23.
The article deals with experimental determination of ionization constants and solubility for the compounds (target products, initial β-lactams, acylating agents and by-products) involved in enzymatic synthesis of some therapeutically used aminopenicillins and aminocephalosporins, namely ampicillin,
PMID 21698348

Determination of cephalosporins in solid binary mixtures by polarized IR- and Raman spectroscopy.

Koleva BB1, Kolev TM, Spiteller M.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2008 Sep 10;48(1):201-4. doi: 10.1016/j.jpba.2008.04.026. Epub 2008 May 4.
Quantitative IR- and Raman spectroscopic determinations of four cephalosporin antibiotics in six solid binary mixtures have been conducted. This is a new approach for spectroscopic determination of these antibiotics, since the corresponding quantitative analysis in solution only has been reported so
PMID 18602240

Metabolite anion carriers mediate the uptake of the anionic drug fluorescein in renal cortical mitochondria.

Terlouw SA1, Tanriseven O, Russel FG, Masereeuw R.
The Journal of pharmacology and experimental therapeutics.J Pharmacol Exp Ther.2000 Mar;292(3):968-73.
The fluorescent organic anion fluorescein (FL) accumulates in proximal tubular cells of the kidney during renal secretion. In freshly isolated and permeabilized proximal tubular cells, the uptake was reduced but still sensitive to probenecid, suggesting a concentrative mechanism that is associated w
PMID 10688611

Determination of β-Lactam Antibiotics in Water by Fluorescence Quenching of Mercurochrome, and Application for Simple Investigation of Potency

森逸男,藤田芳一,生田絹子,北野尚子,川辺博司,中橋義弘,加藤圭司,稲森善彦
Chemical & pharmaceutical bulletin 37(7), 1827-1830, 1989-07-25
… The calibration graphs were linear over the ranges of about 0-6 μg/ml β-lactam antibiotics penicillins (AB-PC, penicillin G, sulbenicillin, amoxicillin, cyclacillin, oxacillin, hetacillin and piperacillin) and cepham antibiotics (CEX, cefazolin, cephaloglycin, cephaloridine and cefpyramide), and the relative standard deviation was 2.7% for 1.4 μg/ml of AB-PC(n=5).This fluorescence quenching reaction between mercurochrome and β-lactam antibiotics was applied in a survey of decomposition and remaining potency of β-lactam antibiotics. …
NAID 110003627868

Determination of .BETA.-lactam antibiotics in water by fluorescence quenching of mercurochrome, and application for simple investigation of potency.

森逸男,藤田芳一,生田絹子,北野尚子,川辺博司,中橋義弘,加藤圭司,稲森善彦
Chemical and Pharmaceutical Bulletin 37(7), 1827-1830, 1989
… The calibration graphs were linear over the ranges of about 0-6 μg/ml β-lactam antibiotics penicillins (AB-PC, penicillin G, sulbenicillin, amoxicillin, cyclacillin, oxacillin, hetacillin and piperacillin) and cepham antibiotics (CEX, cefazolin, cephaloglycin, cephaloridine and cefpyramide), and the relative standard deviation was 2.7% for 1.4 μg/ml of AB-PC(n=5).This fluorescence quenching reaction between mercurochrome and β-lactam antibiotics was applied in a survey of decomposition and remaining potency of β-lactam antibiotics. …
NAID 130003771642

Physicochemical Properties of Amphoteric β-Lactam Antibiotics. III. Stability, Solubility, and Dissolution Behavior of Cefatrizine and Cefadroxil as a Function of pH

辻彰,中島恵美,西出和憲,出口芳春,浜野正一郎,山名月中
Chemical & pharmaceutical bulletin 31(11), 4057-4069, 1983-11-25
… The intramolecular reaction rate was very similar to that of cephaloglycin, but ten times faster than those for cefadroxil, cephalexin, and cefradine under the same conditions. …
NAID 110003624151

Cefaloglycin
Systematic (IUPAC) name
	(6R,7R)-3-[(acetyloxy)methyl]-7-{[(2R)-2-amino-2-phenylacetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS Number	3577-01-3
ATC code	None
PubChem	CID: 19150
DrugBank	DB00689
ChemSpider	18069
UNII	HD2D469W6U
KEGG	D01949
ChEBI	CHEBI:34613
ChEMBL	CHEMBL1200971
Chemical data
Formula	C18H19N3O6S
Molecular mass	405.426 g/mol
	SMILES O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccccc3)N)COC(=O)C)C(=O)O ;
	InChI InChI=1S/C18H19N3O6S/c1-9(22)27-7-11-8-28-17-13(16(24)21(17)14(11)18(25)26)20-15(23)12(19)10-5-3-2-4-6-10/h2-6,12-13,17H,7-8,19H2,1H3,(H,20,23)(H,25,26)/t12-,13-,17-/m1/s1 ; Key:FUBBGQLTSCSAON-PBFPGSCMSA-N ;
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