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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/10/14 23:45:58」(JST)

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  • ZO-1 expression shows prognostic value in chronic B cell leukemia.
  • Nesmiyanov PP1, Tolkachev BE2, Strygin AV3.
  • Immunobiology.Immunobiology.2016 Jan;221(1):6-11. doi: 10.1016/j.imbio.2015.08.008. Epub 2015 Aug 17.
  • Connexin-mediated gap junctions are vital for tumor cell function. Intracellular pathways of connexin signaling use Zonula Occludens protein-1 (ZO-1) as an intermediate. This report describes the ZO-1 and connexin 43 (Cx43) expression pattern in lymphocytes from chronic B-cell leukemia (B-CLL) patie
  • PMID 26306999
  • EGF-Induced Connexin43 Negatively Regulates Cell Proliferation in Human Ovarian Cancer.
  • Qiu X1, Cheng JC1, Klausen C1, Chang HM1, Fan Q1, Leung PC1.
  • Journal of cellular physiology.J Cell Physiol.2016 Jan;231(1):111-9. doi: 10.1002/jcp.25058.
  • Connexin43 (Cx43) has been shown to regulate cell proliferation and its downregulation is correlated with poor prognosis and survival in several types of human cancer. Cx43 expression levels are frequently downregulated in human ovarian cancer, suggesting a potential role for Cx43 in regulating the
  • PMID 26031779
  • Protective effect of Carbenoxolone on ER stress-induced cell death in hypothalamic neurons.
  • Kim J1, Jung EJ2, Moon SS3, Seo M4.
  • Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Nov 11. pii: S0006-291X(15)30904-9. doi: 10.1016/j.bbrc.2015.11.034. [Epub ahead of print]
  • Hypothalamic endoplasmic reticulum (ER) stress is known to be increased in obesity. Induction of ER stress on hypothalamic neurons has been reported to cause hypothalamic neuronal apoptosis and malfunction of energy balance, leading to obesity. Carbenoxolone is an 11β-hydroxysteroid dehydrogenase t
  • PMID 26577412


  • Extracellular ATP Evokes Infiltration of Macrophage in Stretched Atrium
  • Sasano Tetsuo,Oishi Sakiko,Tamura Noriko,Isobe Mitsuaki,Furukawa Tetsushi
  • Journal of Arrhythmia 27(Supplement), SY11_3-SY11_3, 2011
  • … Murine macrophages were co-cultured with mechanically stretched HL-1 dells using modified Boyden chamber, with or without drugs including carbenoxolone (CBX, a gap junction channel blocker), apyrase, and pyridoxalphosphate-6-azophenyl-2′,4′-disulphonic acid (PPADS). …
  • NAID 130002130386
  • Inhibition of 11.BETA.-Hydroxysteroid Dehydrogenase Improves Glucose Metabolism in Insulin Resistant Otsuka Long-Evans Tokushima Fatty Rats
  • Kim Dong-Sun,Park Yoo-Sin,Kim Shin-Hee,Kim Young-Hoon,Jhee Ok-Hwa,Lee Seong-Jin,Kim Tae-Wha,Kang Ju-Seop
  • JOURNAL OF HEALTH SCIENCE 57(4), 378-383, 2011
  • … The present study was examined whether inhibition of 11β-HSD-1 by carbenoxolone (CBX), a non-selective 11β-HSD inhibitor, improved carbohydrate metabolism in insulin resistant Otsuka Long-Evans Tokushima Fatty (OLETF) rats or not. …
  • NAID 130001001084



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