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  • Autophagy switches to apoptosis in prostate cancer cells infected with melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24).
  • Bhutia SK, Das SK, Azab B, Dash R, Su ZZ, Lee SG, Dent P, Curiel DT, Sarkar D, Fisher PB.SourceDepartment of Human and Molecular Genetics; Virginia Commonwealth University School of Medicine; Richmond, VA USA; Department of Life Science; National Institute of Technology; Rourkela, Orissa India.
  • Autophagy.Autophagy.2011 Sep 1;7(9). [Epub ahead of print]
  • MDA-7/IL-24 has noteworthy potential as an anticancer therapeutic because of its diversity of antitumor properties, its lack of toxicity toward normal cells and tissues, and its safety and efficacy as evidenced in a phase I clinical trial. In a recent study, we document that Ad.mda-7-induced ER stre
  • PMID 21610321
  • Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease.
  • Sagredo O, Pazos MR, Satta V, Ramos JA, Pertwee RG, Fernandez-Ruiz J.SourceDepartamento de Bioquimica y Biologia Molecular, Instituto Universitario de Investigacion en Neuroquimica, Universidad Complutense, Madrid, Spain; Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universidad Complutense, Madrid, Spain; Instituto Ramon y Cajal de Investigacion Sanitaria (IRYCIS), Facultad de Medicina, Universidad Complutense, Madrid, Spain.
  • Journal of neuroscience research.J Neurosci Res.2011 Sep;89(9):1509-18. doi: 10.1002/jnr.22682. Epub 2011 Jun 14.
  • We studied whether combinations of botanical extracts enriched in either Δ(9) -tetrahydrocannabinol (Δ(9) -THC) or cannabidiol (CBD), which are the main constituents of the cannabis-based medicine Sativex, provide neuroprotection in rat models of Huntington's disease (HD). We used rats intoxicated
  • PMID 21674569


  • 胃粘膜防御に果たすカルパインの役割 (特集 NSAIDs潰瘍--最新の予防・治療) -- (特論)
  • 秦 勝志,反町 洋之
  • 日本臨床 69(6), 1116-1122, 2011-06
  • NAID 40018850039
  • 脳虚血による神経細胞死における恒常的活性型カルシニューリンの機能的役割
  • 塩田 倫史,福永 浩司
  • YAKUGAKU ZASSHI 131(1), 13-20, 2011
  • … In a mouse middle cerebral artery occlusion (MCAO) model, calpain, a Ca2+-dependent cysteine protease, converted CaN to the constitutively active form of 48 kDa in vivo. … The calpain-induced CaN activation mediated delayed neuronal death through translocation of nuclear factor of activated T-cells (NFAT) and FKHR, a forkhead box class O family member (FOXO) into neuronal nuclei after brain ischemia. …
  • NAID 130000451520


A calpain is a protein belonging to the family of calcium-dependent, non- lysosomal cysteine proteases (proteolytic enzymes) expressed ubiquitously in mammals and many other organisms. Calpains constitute the C2 family of protease clan ...


Calpain; Calcium-Activated Neutral Calpain; Calcium-Activated Neutral neutral proteinase; calpain i; calpain Calpain; Calcium-Activated Neutral  cyclical ca 2 calpain g α s and camp epacrat capn2 s1 m calpain calpain net

拡張検索calpain subunit



カルシウム依存性中性プロテアーゼ calcium dependent neutral protease CDNP, calcium-activated neutral protease
  • プロセシングに関与するシステインプロテアーゼの一種

calpain subunit」

  [★] カルパインサブユニット

"" より作成




1user/password 20
2ミタゾラム 効果 16
3Jardine, A., Neville, P. J., Dent, C., Webster, C., & Lindsay, M. D. (2014). Ross River virus risk associated with dispersal of Aedes (Ochlerotatus) camptorhynchus (Thomson) from breeding habitat into surrounding residential areas: muddy lakes, Western Australia. American Journal of Tropical Medicineand Hygiene, 91(1), 101-108. doi:10.4269/ajtmh.13-0399 16
4化生 特徴 15
5多毛日本 12
61,1024,768,24 HTTP/1.1 8
7user/register 8
8ラクテック 8
9cefpodoxime proxetil BCS 8
10盲斑 7
111,320,568,24 HTTP/1.1 7
12日常生活自立度 6
13Salivary glands 5
14viraldeath解剖 5
15ルリッシュ症候群 5
16サイズの原理 筋電図 5
17メトロイリーゼ 4
18?mesterolon? Britain 4
19vitブラウザの1時間2.3時間を見る方法 4
20ハルトマン 4

1user/password 9
2医の倫理 国際網領 4
3ハルトマン 3
4ソルデム 3
5顔面失行 3
6動脈血柱反射 3
7ワレンベルグ症候群 3
8monnro-kou 3
9扁平コンジローマ 3
10サーモグラフィー 末梢循環障害 2
11化学性腹膜炎 2
12高カルシウム血症 2
13シンプソン徴候 2
14自動性 2
15眼球圧迫法 2
16ポイツイエーガー症候群 2
17albright 症候群 2
18心窩部痛 2
19シドフォビル 2
20強皮症 下部食道蠕動運動 2