biological response modifiers

出典: meddic

生物学的応答調節物質 BRM

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/03/17 13:40:57」(JST)

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  • Prenatal immune activation in mice blocks the effects of environmental enrichment on exploratory behavior and microglia density.
  • Buschert J1, Sakalem ME2, Saffari R2, Hohoff C2, Rothermundt M3, Arolt V1, Zhang W1, Ambrée O4.
  • Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2016 Jun 3;67:10-20. doi: 10.1016/j.pnpbp.2016.01.005. Epub 2016 Jan 14.
  • Adverse environmental factors including prenatal maternal infection are capable of inducing long-lasting behavioral and neural alterations which can enhance the risk to develop schizophrenia. It is so far not clear whether supportive postnatal environments are able to modify such prenatally-induced
  • PMID 26776071
  • A best practice position statement on pregnancy in chronic kidney disease: the Italian Study Group on Kidney and Pregnancy.
  • Cabiddu G1, Castellino S2, Gernone G3, Santoro D4, Moroni G5, Giannattasio M6, Gregorini G7, Giacchino F8, Attini R9, Loi V1, Limardo M10, Gammaro L11, Todros T9, Piccoli GB12,13.
  • Journal of nephrology.J Nephrol.2016 Jun;29(3):277-303. doi: 10.1007/s40620-016-0285-6. Epub 2016 Mar 17.
  • Pregnancy is increasingly undertaken in patients with chronic kidney disease (CKD) and, conversely, CKD is increasingly diagnosed in pregnancy: up to 3 % of pregnancies are estimated to be complicated by CKD. The heterogeneity of CKD (accounting for stage, hypertension and proteinuria) and the rari
  • PMID 26988973
  • Predictors of soft-tissue complications and deep infection in allograft reconstruction of the proximal tibia.
  • Lozano-Calderón SA1, Swaim SO2, Federico A3, Anderson ME1, Gebhardt MC1.
  • Journal of surgical oncology.J Surg Oncol.2016 Jun;113(7):811-7. doi: 10.1002/jso.24234. Epub 2016 Apr 29.
  • BACKGROUND AND OBJECTIVES: Reconstruction of the proximal tibia after wide resection of malignant tumors in the pediatric population is very challenging. Advocates of allograft reconstruction argue as advantages bone preservation, biological reconstruction that facilitates reattachment of the extens
  • PMID 27126893


  • ぶどう膜炎の病態と新規治療
  • 柳井 亮二,武田 篤信,吉村 武,園田 康平
  • 日本臨床免疫学会会誌 37(2), 74-82, 2014
  •   ぶどう膜炎とは,狭義には「ぶどう膜組織の炎症」であるが,臨床的には「眼内の全ての炎症」を指す.ぶどう膜炎は単一の疾患概念ではなく,自己免疫疾患,感染症,造血器悪性腫瘍など多種多様な原因や背景をもとに発症する.ぶどう膜炎の多くは再発する可能性のある慢性病であり,姑息的に眼炎症をコントロールするだけでなく,長期的観点から患者の視機能の維持を考える必要がある.Behçét病は,放置すれば中途失明に至 …
  • NAID 130004875918
  • 臨床への応用(がんに対する免疫療法の現状と展望,会員のための企画)
  • ATMを介してRBタンパク質はDNMT1タンパク質の安定性とDNAメチル化を制御する
  • Shamma Awad,Suzuki Misa,Hayashi Naoyuki,Kobayashi Masahiko,Sasaki Nobunari,Nishiuchi Takumi,Doki Yuichiro,Okamoto Takahiro,Kohno Susumu,Muranaka Hayato,Kitajima Shunsuke,Yamamoto Ken-ichi,Takahashi Chiaki
  • Molecular biology of the cell 33(16), 3113-3124, 2013-08
  • … The retinoblastoma tumor suppressor gene (RB) product has been implicated in epigenetic control of gene expression owing to its ability to physically bind to many chromatin modifiers. … However, the biological and clinical significance of this activity was not well elucidated. … Our results indicate that inactivation of the pRB pathway in coordination with aberration in the DNA damage response deregulates DNMT1 stability, leading to an abnormal DNA methylation pattern and malignant progression. …
  • NAID 120005312327


biological response modifiers, substances such as phytochemicals and fibers that modulate mech-anisms related to the development of disease, such as hormonal changes, immune function, inflammatory activity, oxidative ...
We have seen a surge in the use of immunotherapy for the treatment of cancer. Biological response modifiers can act passively by enhancing the immunologic response to tumor cells or actively by altering the ...



関連記事response」「modifier」「biological」「biologic」「biological response



biological response modifierBRM





  • n.

WordNet   license wordnet

「a result; "this situation developed in response to events in Africa"」

WordNet   license wordnet

「a phrase recited or sung by the congregation following a versicle by the priest or minister」

WordNet   license wordnet

「the manner in which an electrical or mechanical device responds to an input signal or a range of input signals」

PrepTutorEJDIC   license prepejdic

「〈C〉(…に対する)『返事』,『返答』《+『to』+『名』》 / 〈C〉〈U〉(…に対する)『反応』,『反響』《『to』+『名』》 / 〈C〉応答歌,応唱(牧師にならって合唱隊・会衆が短い祈り・歌を応答すること)」



  • n.
effect modifiermodifying factormodulator

WordNet   license wordnet

「a gene that modifies the effect produced by another gene」
modifier gene

WordNet   license wordnet

「a content word that qualifies the meaning of a noun or verb」

WordNet   license wordnet

「a moderator who makes less extreme or uncompromising」

PrepTutorEJDIC   license prepejdic




  • adj.
  • 生物学的な、生物学の、生物学上の、生物の

WordNet   license wordnet

「of parents and children; related by blood; "biological child"」

WordNet   license wordnet

「pertaining to biology or to life and living things」



  • adj.
  • 生物学的な、生物学の、生物学上の、生物の

biological response」