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1. 過敏性腸症候群に対するアロセトロン塩酸塩（Lotronex） alosetron hydrochloride lotronex for irritable bowel syndrome
2. 早産児における非経口栄養 parenteral nutrition in premature infants
3. 変形性関節症の薬物療法に対する実験的アプローチ investigational approaches to the pharmacologic therapy of osteoarthritis
4. コーガン症候群 cogans syndrome
5. 局所麻酔剤に対するアレルギー反応 allergic reactions to local anesthetics

Effects of bifemelane on the calcium level and ATP release of the human origin astrocyte clonal cell.

Yoshida Y, Kumagai H, Ohkubo Y, Tsuchiya R, Morita M, Miyakawa H, Kudo Y.SourceSchool of Life Science, Tokyo University of Pharmacy and Life Science, Japan.
Journal of pharmacological sciences.J Pharmacol Sci.2006 Sep;102(1):121-8. Epub 2006 Sep 15.
The effect of bifemelane hydrochloride (bifemelane) was examined on human origin astrocyte clonal cells (Kings-1). Bifemelane (125 - 1,000 microM) induced a dose-dependent increase in the intracellular calcium concentration ([Ca(2+)](i)). In the highest concentration (1,000 microM), the drug caused
PMID 16974067

A novel effect of bifemelane, a nootropic drug, on intracellular Ca2+ levels in rat cerebral astrocytes.

Yoshida Y, Nakane A, Morita M, Kudo Y.SourceSchool of Life Science, Tokyo University of Pharmacy and Life Science, Tokyo, Japan.
Journal of pharmacological sciences.J Pharmacol Sci.2006 Feb;100(2):126-32. Epub 2006 Feb 11.
We investigated the effects of bifemelane, a nootropic drug, on the intracellular calcium concentration ([Ca2+]i) in rat cerebral astrocytes using a Ca2+ imaging device. At concentrations of 10 - 30 microM, bifemelane induced a slow onset and small increase in the [Ca2+]i, while at higher concentrat
PMID 16474207

Involvement of cholinergic and GABAergic systems in the reversal of memory disruption by NS-105, a cognition enhancer.

Ogasawara T, Itoh Y, Tamura M, Mushiroi T, Ukai Y, Kise M, Kimura K.SourceResearch Laboratories, Nippon Shinyaku Co., Ltd., Kyoto, Japan.
Pharmacology, biochemistry, and behavior.Pharmacol Biochem Behav.1999 Sep;64(1):41-52.
The effects of (+)-5-oxo-D-prolinepiperidinamide monohydrate (NS-105) on the scopolamine-, electrolytic lesion of the nucleus basalis magnocellularis (NBM)-, AF64A-, baclofen-, cerebral ischemia- and electroconvulsive shock (ECS)-induced memory disruption in the passive avoidance response or radial
PMID 10494996