WordNet

a straight line segment whose length is magnitude and whose orientation in space is direction
(genetics) a virus or other agent that is used to deliver DNA to a cell
any agent (person or animal or microorganism) that carries and transmits a disease; "mosquitos are vectors of malaria and yellow fever"; "fleas are vectors of the plague"; "aphids are transmitters of plant diseases"; "when medical scientists talk about vectors they are usually talking about insects" (同)transmitter
a variable quantity that can be resolved into components
not arising from natural growth or characterized by vital processes
artificially formal; "that artificial humility that her husband hated"; "contrived coyness"; "a stilted letter of acknowledgment"; "when people try to correct their speech they develop a stilted pronunciation" (同)contrived, hokey, stilted
contrived by art rather than nature; "artificial flowers"; "artificial flavoring"; "an artificial diamond"; "artificial fibers"; "artificial sweeteners" (同)unreal
(microbiology) single-celled or noncellular spherical or spiral or rod-shaped organisms lacking chlorophyll that reproduce by fission; important as pathogens and for biochemical properties; taxonomy is difficult; often considered to be plants (同)bacterium
relating to or caused by bacteria; "bacterial infection"
a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"

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Efficient heterologous antigen gene delivery and expression by a replication-attenuated BoHV-4-based vaccine vector.

Capocefalo A, Mangia C, Franceschi V, Jacca S, van Santen VL, Donofrio G.SourceDipartimento di Scienze Medico-Veterinarie, Università di Parma, via del Taglio 10, 43126 Parma, Italy.
Vaccine.Vaccine.2013 Aug 20;31(37):3906-14. doi: 10.1016/j.vaccine.2013.06.052. Epub 2013 Jul 3.
Bovine Herpesvirus 4 (BoHV-4) is a gammaherpesvirus belonging to the Rhadinovirus genus and due to its biological characteristics has been proposed as a vaccine vector for veterinary vaccines. Because viral vector-associated risk is a major concern for viral vector applications, attenuation is a des
PMID 23830977

Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer.

Brueckner LM, Hess EM, Schwab M, Savelyeva L.SourceDivision of Tumor Genetics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.
Cancer letters.Cancer Lett.2013 Aug 9;336(1):85-95. doi: 10.1016/j.canlet.2013.04.007. Epub 2013 Apr 16.
Specific patterns of genomic aberrations have been associated with different types of malignancies. In colorectal cancer, losses of chromosome arm 8p and gains of chromosome arm 8q are among the most common chromosomal rearrangements, suggesting that the centromeric portion of chromosome 8 is partic
PMID 23603433

Transcription of a protein-coding gene on B chromosomes of the Siberian roe deer (Capreolus pygargus).

Trifonov VA, Dementyeva PV, Larkin DM, O'Brien PC, Perelman PL, Yang F, Ferguson-Smith MA, Graphodatsky AS.SourceInstitute of Molecular and Cellular Biology SВ RAS, Novosibirsk, Russia. vlad@mcb.nsc.ru
BMC biology.BMC Biol.2013 Aug 6;11:90. doi: 10.1186/1741-7007-11-90.
BACKGROUND: Most eukaryotic species represent stable karyotypes with a particular diploid number. B chromosomes are additional to standard karyotypes and may vary in size, number and morphology even between cells of the same individual. For many years it was generally believed that B chromosomes fou
PMID 23915065

Construction of an Expressible BAC Library of the Unculturable Insect Microorganism, Stink Bug Plautia stali Symbiont, for the Search of Biologically Active and Useful Symbiont Products

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Biological and Pharmaceutical Bulletin 37(4), 528-533, 2014
… In this study, the possibility of using bacterial artificial chromosome (BAC) libraries as a heterologous gene expression tool for the discovery of novel symbiont metabolites was evaluated. … the clones contained the leu operon of the symbiont chromosome. … stali symbiont genes introduced into the BAC vector are functional in E. …
NAID 130003390956

田辺寛之,松浦喜徳
近畿大学農学部紀要 (46), 1-14, 2013
… BAC (bacterial artificial chromosome)-mediated transgenesis is a powerful technology that facilitates spatial and temporal modulation of gene expression in vivo. …
NAID 120005298690

Application of a Bacterial Artificial Chromosome Modification System for a Human Artificial Chromosome Vector

Yamaguchi Shigeyuki,Niwa Ryosuke,Kazuki Yasuhiro,Ohbayashi Tetsuya
Yonago Acta medica 54(1), 21-31, 2011-03
… Bacterial artificial chromosomes (BACs) are optimal for harboring long fragments of genomic DNA or large cDNA up to 300 kb in size. … We previously developed a human artiﬁcial chromosome (HAC) vector from human chromosome 21 using chromosome engineering. …
NAID 120002854451