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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/12/17 17:13:00」(JST)

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  • Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells.
  • Zhou C, Pan W, Wang XP, Chen TS.SourceMOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou, China.
  • Journal of cellular physiology.J Cell Physiol.2012 Dec;227(12):3778-86. doi: 10.1002/jcp.24086.
  • This report is designed to explore the exact molecular mechanism by which artesunate (ART), a semisynthetic derivative of the herbal antimalaria drug artemisinin, induces apoptosis in human lung adenocarcinoma (ASTC-a-1 and A549) cell lines. ART treatment induced ROS-mediated apoptosis in a concentr
  • PMID 22378505
  • Pharmacokinetics and Pharmacodynamics of Oral Artesunate Monotherapy in Patients with Uncomplicated Plasmodium falciparum Malaria in Western Cambodia.
  • Saunders D, Khemawoot P, Vanachayangkul P, Siripokasupkul R, Bethell D, Tyner S, Se Y, Rutvisuttinunt W, Sriwichai S, Chanthap L, Lin J, Timmermans A, Socheat D, Ringwald P, Noedl H, Smith B, Fukuda M, Teja-Isavadharm P.SourceDepartment of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand.
  • Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2012 Nov;56(11):5484-93. doi: 10.1128/AAC.00044-12. Epub 2012 Aug 6.
  • Artemisinin-resistant malaria along the Thailand-Cambodian border is an important public health concern, yet mechanisms of drug action and their contributions to the development of resistance are poorly understood. The pharmacokinetics and pharmacodynamics of oral artesunate monotherapy were explore
  • PMID 22869581


  • Artemisinin-based combination therapies and their introduction in Japan
  • KANO Shigeyuki
  • Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 16(6), 375-382, 2010-12-01
  • NAID 10027655912
  • Artesunate inhibiting angiogenesis induced by human myeloma RPMI8226 cells
  • CHEN Hao,SHI Liang,YANG Xiaoyang,LI Shihui,GUO Xiaoling,PAN Ling
  • International journal of hematology 92(4), 587-597, 2010-11-15
  • NAID 10027673888


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Uses [edit source | edit] Artesunate is used primarily as treatment for malaria; it has also been shown to be >90% efficacious at reducing egg production in Schistosoma haematobium infection. [1] According to WHO intravenous AS ...


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