arachidonic acid cyclooxygenase

アラキドン酸シクロオキシゲナーゼ

WordNet

1. street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
2. any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
3. having the characteristics of an acid; "an acid reaction"
4. either of two related enzymes that control the production of prostaglandins and are blocked by aspirin (同)Cox

PrepTutorEJDIC

1. 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD

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• 1. 非ステロイド性抗炎症剤（NSAIDs）：作用機序 nsaids mechanism of action
• 2. アスピリンによる呼吸器疾患の増悪 aspirin exacerbated respiratory disease
• 3. COX-2選択的阻害剤の概要 overview of selective cox 2 inhibitors
• 4. アスピリン：リウマチ性疾患における作用機序、主な毒性、および使用 aspirin mechanism of action major toxicities and use in rheumatic diseases
• 5. 切迫早産の予防 inhibition of acute preterm labor

English Journal

• Lipoxins and aspirin-triggered lipoxins in resolution of inflammation.

• Romano M1, Cianci E2, Simiele F3, Recchiuti A3.
• European journal of pharmacology.Eur J Pharmacol.2015 Aug 5;760:49-63. doi: 10.1016/j.ejphar.2015.03.083. Epub 2015 Apr 18.
• The resolution of the inflammatory response is highly regulated by the timely biosynthesis of a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers, aspirin triggered lipoxins (ATL) derived by the lipoxygenase (LO) route of arachidonic acid metabolism. In particular
• PMID 25895638

• Possible inhibitory role of endogenous 2-arachidonoylglycerol as an endocannabinoid in (±)-epibatidine-induced activation of central adrenomedullary outflow in the rat.

• Shimizu T1, Tanaka K2, Shimizu S3, Higashi Y3, Yawata T4, Nakamura K3, Taniuchi K5, Ueba T4, Yuri K2, Saito M3.
• Neuropharmacology.Neuropharmacology.2015 Aug;95:278-89. doi: 10.1016/j.neuropharm.2015.03.034. Epub 2015 Apr 14.
• We previously reported that intracerebroventricularly (i.c.v.) administered (±)-epibatidine (1, 5 or 10 nmol/animal), a nicotinic acetylcholine receptor agonist, dose-dependently induced secretion of noradrenaline and adrenaline (catecholamines) from the rat adrenal medulla by brain diacylglycerol
• PMID 25882827
• PMID 25789542

Japanese Journal

• Current Perspective : The Role of Sphingolipids in Arachidonic Acid Metabolism

• Nakamura Hiroyuki,Murayama Toshihiko
• Journal of pharmacological sciences 124(3), 307-312, 2014-03
• NAID 40020026355

• The Expression of Groups IIE and V Phospholipase A2 is Associated with an Increased Expression of Osteogenic Molecules in Human Calcified Aortic Valves

• Suzuki Koji,Takahashi Soichiro,Watanabe Kazuhiro,Fujioka Daisuke,Nakamura Takamitsu,Obata Jun-ei,Kawabata Ken-ichi,Katoh Ryohei,Matsumoto Masahiko,Kugiyama Kiyotaka
• Journal of Atherosclerosis and Thrombosis 21(12), 1308-1325, 2014
• … Eicosanoids are derived from the arachidonic acid generated by phospholipase A2 (PLA2). … In addition, immunoreactivity for cyclooxygenase (COX)-1, COX-2 and 5-lipoxygenase, downstream enzymes of PLA2 in the arachidonic acid cascade, was co-localized with that for PLA2s-IIE and -V in cells expressing α-smooth muscle actin and macrophages expressing CD68. …
• NAID 130004845466

• Dioscorea japonica extract down-regulates prostaglandin E2 synthetic pathway and induces apoptosis in lung cancer cells

• Suzuki-Yamamoto Toshiko,Tanaka Sayuri,Tsukayama Izumi,Takafuji Miki,Hanada Takae,Arakawa Toshiya,Kawakami Yuki,Kimoto Masumi,Takahashi Yoshitaka
• Journal of Clinical Biochemistry and Nutrition 55(3), 162-167, 2014
• … Prostaglandin E2 is synthesized from arachidonic acid by the enzymes cyclooxygenase and prostaglandin E synthase. … In some pathological conditions, the isozymes cyclooxygenase-2 and microsomal prostaglandin E synthase-1 are transiently induced, leading to prostaglandin E2 overproduction. …
• NAID 130004687668

Related Links

• Arachidonic Acid - Home - ACNP

Arachidonic Acid Daniele Piomelli Professor of Pharmacology; 360 Med Surge II; University of California, Irvine; Irvine, CA 92697-4625. A TALE OF TWO ROLES When a neurotransmitter binds to its receptor on the membrane of a ...

• Arachidonic Acid Oxygenation by COX-1 and COX-2

Cyclooxygenase Catalysis Substantial evidence supports the hypothesis that COX oxygenates arachidonic acid by a free radical mechanism (Fig. 1). Thus, COX appears to have co-opted the process that gives rise to isoprostanes to ...

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★リンクテーブル★

リンク元	「アラキドン酸シクロオキシゲナーゼ」
関連記事	「cyclooxygenase」

「アラキドン酸シクロオキシゲナーゼ」

　　[★]

英

arachidonic acid cyclooxygenase

「cyclooxygenase」

　　[★] シクロオキシゲナーゼ