apoA-I

出典: meddic

  • ア・リ・タンパク質A-I、ア・リ・蛋白A-I、ア・A-I
apo A-I、apo A1、apolipoprotein A-I、apolipoprotein A1、apolipoprotein AI

UpToDate Contents

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英文文献

  • High-density lipoprotein attenuates Th1 and th17 autoimmune responses by modulating dendritic cell maturation and function.
  • Tiniakou I1, Drakos E2, Sinatkas V2, Van Eck M3, Zannis VI4, Boumpas D5, Verginis P6, Kardassis D7.
  • Journal of immunology (Baltimore, Md. : 1950).J Immunol.2015 May 15;194(10):4676-87. doi: 10.4049/jimmunol.1402870. Epub 2015 Apr 13.
  • Aberrant levels and function of the potent anti-inflammatory high-density lipoprotein (HDL) and accelerated atherosclerosis have been reported in patients with autoimmune inflammatory diseases. Whether HDL affects the development of an autoimmune response remains elusive. In this study, we used apol
  • PMID 25870241
  • Association of elevated apoA-I glycation and reduced HDL-associated paraoxonase1, 3 activity, and their interaction with angiographic severity of coronary artery disease in patients with type 2 diabetes mellitus.
  • Shen Y1, Ding FH2, Sun JT3, Pu LJ4, Zhang RY5, Zhang Q6, Chen QJ7, Shen WF8,9, Lu L10,11.
  • Cardiovascular diabetology.Cardiovasc Diabetol.2015 May 13;14:52. doi: 10.1186/s12933-015-0221-4.
  • OBJECTIVE: To investigate whether apolipoprotein A (apoA)-I glycation and paraoxonase (PON) activities are associated with the severity of coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM).METHODS: Relative intensity of apoA-I glycation and activities of high-density lip
  • PMID 25964115
  • The effect of natural LCAT mutations on the biogenesis of HDL.
  • Fotakis P, Kuivenhoven JA, Dafnis E, Kardassis D, Zannis VI.
  • Biochemistry.Biochemistry.2015 May 7. [Epub ahead of print]
  • We have investigated how the natural LCAT[T147I] and LCAT[P274S] mutations affect the pathway of biogenesis of HDL. Gene transfer of WT LCAT in LCAT-/- mice increased 11.8 fold the plasma cholesterol whereas the LCAT[T147I] and LCAT[P274S] mutants caused a 5.2 and 2.9 fold increase respectively. The
  • PMID 25948084

和文文献

  • Synthesis of ^<68>Ga-DOTA-FAMP and PET Imaging Study with Atherosclerotic Plaques
  • HASEGAWA Koki,KAWACHI Emi,KUWABARA Ren,YAHIRO Eiji,ANDO Setsuko,ONIKI Kousuke,ADACHI Ryuta,WADA Yasuhiro,YANO Tsuneo,UEHARA Yoshinari,MIURA Shin-ichiro,SAKU Keijiro,WATANABE Yasuyoshi
  • Peptide science : proceedings of the ... Japanese Peptide Symposium 2011, 291-294, 2012-03-01
  • NAID 10030204424
  • Correlation of Structure in Solution and Lipid Affinity of ApolipoproteinA-I Mimetic Peptide (II)
  • ADACHI Ryuta,ONIKI Kousuke,AOYAGI Haruhiko,ABE Satomi,UEHARA Yoshinari,SAKU Keijiro,YAMADA Keiichi,ANDO Setsuko
  • Peptide science : proceedings of the ... Japanese Peptide Symposium 2011, 237-240, 2012-03-01
  • NAID 10030204323
  • Astaxanthin Enhances ATP-Binding Cassette Transporter A1/G1 Expressions and Cholesterol Efflux from Macrophages
  • IIZUKA Maki,AYAORI Makoto,UTO-KONDO Harumi,YAKUSHIJI Emi,TAKIGUCHI Shunichi,NAKAYA Kazuhiro,HISADA Tetsuya,SASAKI Makoto,KOMATSU Tomohiro,YOGO Makiko,KISHIMOTO Yoshimi,KONDO Kazuo,IKEWAKI Katsunori
  • Journal of Nutritional Science and Vitaminology 58(2), 96-104, 2012
  • … Astaxanthin enhanced both apolipoprotein (apo) A-I- and HDL-mediated cholesterol efflux from RAW264.7 cells. … In conclusion, astaxanthin increased ABCA1/G1 expression, thereby enhancing apoA-I/HDL-mediated cholesterol efflux from the macrophages in an LXR-independent manner. …
  • NAID 130002103037

関連リンク

ApoA-1 Milano is a naturally occurring mutant of ApoA-I, found in a family descended from a single couple of the 18th century. Described in 1980, it was the first known molecular abnormality of apolipoproteins. Paradoxically, carriers of this ...

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★リンクテーブル★
先読みapolipoprotein A-I
リンク元フィブラート」「アポリポ蛋白A-I」「アポリポタンパク質A-I」「アポA-I
拡張検索apoA-II
関連記事I」「apo」「apoA」「Id

apolipoprotein A-I」

  [★] アポリポタンパク質AI


フィブラート」

  [★]

fibrate
フィブラート系薬物高脂血症治療薬
  • fibric acidの誘導体(fibric acid derivatves)
  • PPAR activators
  • HDL↑、LDL↓
  • peroxisome proliferator activated receptor(PPAR)を介して薬理作用を発現←転写因子
  • PPARα:肝臓、褐色脂肪細胞で発現。腎臓、心臓、骨格筋でやや発現 (GOO.957)
作用:(1)脂肪酸酸化、LPL合成↑、apoC-III↓ (GOO.957)
apoC-IIIは肝臓分解やレセプターを介した(LDLなどの)取り込みのinhibitorとして機能 (GOO.957)
HDL-Cの増加はapoA-IとApoA-IIの発現を刺激することによる (GOO.957)

フィブラート系薬物


アポリポ蛋白A-I」

  [★]

apolipoprotein A-IapoA-I、apo A-I
アポリポタンパクA-Iアポリポタンパク質A-Iアポリポ蛋白質A-IアポA-Iアポリポタンパク質A1アポリポタンパク質AI


アポリポタンパク質A-I」

  [★]

apolipoprotein A-IapoA-I、apo A-I
ア・リ・蛋白A-I、ア・リ・タンパクA-I、ア・リ・蛋白質A-I、ア・A-I


アポA-I」

  [★]

(n
  • apoA-I
ア・リ・蛋白A-I、ア・リ・タンパク質A-I


apoA-II」

  [★]

  • ア・リ・タンパク質A-II、ア・リ・蛋白A-II、ア・A-II
apo A-II、apo A2、apolipoprotein A-II、apolipoprotein A2、apolipoprotein AII


I」

  [★]

WordNet   license wordnet

「the 9th letter of the Roman alphabet」
i

PrepTutorEJDIC   license prepejdic

「『私は』私が」

PrepTutorEJDIC   license prepejdic

「iodineの化学記号」


apo」

  [★]

apolipoprotein


apoA」

  [★]

  • ア・リ・タンパク質A、ア・A
apo A、apolipoprotein A


Id」

  [★]


"http://meddic.jp/apoA-I" より作成


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