出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/11/30 22:07:36」(JST)[Wiki en表示]
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- 1. Management of acute complicated diverticulitis
- 2. 成人における急性副鼻腔炎および鼻副鼻腔炎：治療 acute sinusitis and rhinosinusitis in adults treatment
- 3. 小児における急性中耳炎：治療 acute otitis media in children treatment
- 4. 合併症リスクの低い成人癌患者における発熱性好中球減少症候群の治療および予防 treatment and prevention of neutropenic fever syndromes in adult cancer patients at low risk for complications
- 5. 急性膀胱炎：2歳以上の小児および思春期におけるマネージメントおよび予後 acute cystitis management and prognosis in children older than two years and adolescents
- Lower prevalence of antibiotic-resistant Salmonella on large-scale U.S. conventional poultry farms that transitioned to organic practices.
- Sapkota AR1, Kinney EL2, George A2, Hulet RM3, Cruz-Cano R4, Schwab KJ5, Zhang G4, Joseph SW6.Author information 1Maryland Institute for Applied Environmental Health, University of Maryland, School of Public Health, College Park, MD, United States. Electronic address: email@example.comMaryland Institute for Applied Environmental Health, University of Maryland, School of Public Health, College Park, MD, United States.3Department of Animal Science, Pennsylvania State University, University Park, PA, United States.4Department of Epidemiology and Biostatistics, University of Maryland, School of Public Health, College Park, MD, United States.5Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.6Maryland Institute for Applied Environmental Health, University of Maryland, School of Public Health, College Park, MD, United States; Department of Cell Biology and Molecular Genetics, University of Maryland College Park, College Park, MD, United States.AbstractAs a result of the widespread use of antibiotics in large-scale U.S. poultry production, a significant proportion of Salmonella strains recovered from conventional poultry farms and retail poultry products express antibiotic resistance. We evaluated whether large-scale poultry farms that transitioned from conventional to organic practices and discontinued antibiotic use were characterized by differences in the prevalence of antibiotic-resistant Salmonella compared to farms that maintained conventional practices. We collected poultry litter, water and feed samples from 10 newly organic and 10 conventional poultry houses. Samples were analyzed for Salmonella using standard enrichment methods. Isolates were confirmed using standard biochemical tests and the Vitek®2 Compact System. Antimicrobial susceptibility testing was performed by Sensititre® microbroth dilution. Data were analyzed using Fisher's exact test and generalized linear mixed models. We detected Salmonella in both conventional and newly organic poultry houses. Salmonella Kentucky was the predominant serovar identified, followed by S. Orion, S. Enteritidis, S. Gostrup and S. Infantis. Among S. Kentucky isolates (n=41), percent resistance was statistically significantly lower among isolates recovered from newly organic versus conventional poultry houses for: amoxicillin-clavulanate (p=0.049), ampicillin (p=0.042), cefoxitin (p=0.042), ceftiofur (p=0.043) and ceftriaxone (p=0.042). Percent multidrug resistance (resistance to ≥3 antimicrobial classes) was also statistically significantly lower among S. Kentucky isolates recovered from newly organic poultry houses (6%) compared to those recovered from conventional houses (44%) (p=0.015). To our knowledge, these are the first U.S. data to show immediate, on-farm changes in the prevalence of antibiotic-resistant Salmonella when antibiotics are voluntarily withdrawn from large-scale poultry facilities in the United States.
- The Science of the total environment.Sci Total Environ.2014 Apr 1;476-477:387-92. doi: 10.1016/j.scitotenv.2013.12.005. Epub 2014 Jan 30.
- As a result of the widespread use of antibiotics in large-scale U.S. poultry production, a significant proportion of Salmonella strains recovered from conventional poultry farms and retail poultry products express antibiotic resistance. We evaluated whether large-scale poultry farms that transitione
- PMID 24486494
- Genotyping for severe drug hypersensitivity.
- Karlin E1, Phillips E.Author information 1Vanderbilt University School of Medicine, 1161-21 St Avenue South, A-2200 Medical Center North, Nashville, TN, 37232-2582, USA.AbstractOver the past decade, there have been significant advances in our understanding of the immunopathogenesis and pharmacogenomics of severe immunologically-mediated adverse drug reactions. Such T-cell-mediated adverse drug reactions such as Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug-induced liver disease (DILI) and other drug hypersensitivity syndromes have more recently been shown to be mediated through interactions with various class I and II HLA alleles. Key examples have included the associations of HLA-B*15:02 and carbamazepine induced SJS/TEN in Southeast Asian populations and HLA-B*57:01 and abacavir hypersensitivity. HLA-B*57:01 screening to prevent abacavir hypersensitivity exemplifies a successful translational roadmap from pharmacogenomic discovery through to widespread clinical implementation. Ultimately, our increased understanding of the interaction between drugs and the MHC could be used to inform drug design and drive pre-clinical toxicity programs to improve drug safety.
- Current allergy and asthma reports.Curr Allergy Asthma Rep.2014 Mar;14(3):418. doi: 10.1007/s11882-013-0418-0.
- Over the past decade, there have been significant advances in our understanding of the immunopathogenesis and pharmacogenomics of severe immunologically-mediated adverse drug reactions. Such T-cell-mediated adverse drug reactions such as Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN),
- PMID 24429903
- Escherichia coli belonging to the worldwide emerging epidemic clonal group O25b/ST131: risk factors and clinical implications.
- López-Cerero L1, Navarro MD, Bellido M, Martín-Peña A, Viñas L, Cisneros JM, Gómez-Langley SL, Sánchez-Monteseirín H, Morales I, Pascual A, Rodríguez-Baño J.Author information 1Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario Virgen Macarena, Seville, Spain.AbstractOBJECTIVES: Escherichia coli belonging to clonal group ST131 has emerged as a significant contributor to infection caused by antibiotic-resistant E. coli worldwide. We investigated the risk factors for infections caused by ST131 E. coli and their clinical implications.
- The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2014 Mar;69(3):809-14. doi: 10.1093/jac/dkt405. Epub 2013 Oct 11.
- OBJECTIVES: Escherichia coli belonging to clonal group ST131 has emerged as a significant contributor to infection caused by antibiotic-resistant E. coli worldwide. We investigated the risk factors for infections caused by ST131 E. coli and their clinical implications.METHODS: One thousand and seven
- PMID 24123431
- Change in pharmacokinetics of mycophenolic acid as a function of age in rats and effect of coadministered amoxicillin/clavulanate
- Ishizaki Junko,Tsuda Tomoko,Suga Yukio [他],Ito Satsuki,Arai Kunizo,Sai Yoshimichi,Miyamoto Ken-ichi
- Biological and Pharmaceutical Bulletin 35(7), 1009-1013, 2012
- … We also compared the effect of concomitant amoxicillin/clavulanate combination (CVA/AMPC) on the pharmacokinetics of MPA in 4-week-old and 12-week-old rats (the package insert of CVA/AMPC warns of possible interaction with MPA). …
- NAID 130001872101
- Clonal spread of β-lactamase-producing amoxicillin–clavulanate-resistant (BLPACR) strains of non-typeable Haemophilus influenzae among young children attending a day care in Japan
- Ito Makoto,Hotomi Muneki,Maruyama Yumiko,Hatano Miyako,Sugimoto Hisashi,Yoshizaki Tomokazu,Yamanaka Noboru
- International Journal of Pediatric Otorhinolaryngology 74(8), 901-906, 2010-08
- … β-Lactamase-nonproducing ampicillin-resistant (BLNAR) strains are particularly common in Japan, and β-lactamase-producing amoxicillin-clavulanate resistant (BLPACR) strains are now emerging. …
- NAID 120002260548
- β-lactamase 産生 amoxicillin/clavulanate 耐性インフルエンザ桿菌性肺炎の1例
- 矢野 量三,高柳 昇,鍵山 奈保,原沢 慶次,松下 文,米田 紘一郎,宮原 庸介,山口 昭三郎,徳永 大道,齊藤 大雄,倉島 一喜,生方 幹夫,柳沢 勉,杉田 裕
- 日本呼吸器学会雑誌 = The journal of the Japanese Respiratory Society 46(9), 753-758, 2008-09-10
- NAID 10024822263
- Amoxicillin / Clavulanate (1:2) [AMPC/CVA (1:2)]. アモキシシリン/クラブラン酸, ペニシリン系(β-ラクタマーゼ阻害剤配合). 1. 商品名. 先発品. オーグメンチン配合錠 125SS／オーグメンチン配合錠250RS 【グラクソ・スミスクライン】. 2. 日本における発売 年 ...
- Learn about the prescription medication Augmentin (Amoxicillin Clavulanate), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling.
- オーグメンチン, Augmentin
- アモキシシリン、クラブラン酸、アモキシシリン・クラブラン酸カリウム合剤 amoxicillin-potassium clavulanate combination amoxicillin/clavulanate potassium mixture AMPC/CVA
- Amoxil, Larotid, Polymox, Trimox, Augmentin