WordNet

resulting from or employing derivation; "a derivative process"; "a highly derivative prose style"
a compound obtained from, or regarded as derived from, another compound
(linguistics) a word that is derived from another word; "`electricity is a derivative of `electric"

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do Nascimento PG1, Lemos TL2, Almeida MC1, de Souza JM1, Bizerra AM1, Santiago GM3, da Costa JG4, Coutinho HD4.
Steroids.Steroids.2015 Jul 25. pii: S0039-128X(15)00212-3. doi: 10.1016/j.steroids.2015.07.007. [Epub ahead of print]
In order to develop bioactive lithocholic acid derivatives, we prepared fifteen semi-synthetic compounds through modification at C-3 and/or C-24. The reactions showed yields ranging from 37% to 100%. The structures of all compounds obtained were identified on the basis of their spectral data (IR, MS
PMID 26216208

A renal-targeted triptolide aminoglycoside (TPAG) conjugate for lowering systemic toxicities of triptolide.

Qi B1, Wang X1, Zhou Y1, Han Q1, He L1, Gong T1, Sun X1, Fu Y1, Zhang Z2.
Fitoterapia.Fitoterapia.2015 Jun;103:242-51. doi: 10.1016/j.fitote.2015.04.008. Epub 2015 Apr 11.
Triptolide (TP), a naturally derived compound, is proven effective in the treatment of nephritis and chronic allograft nephropathy. However, the severe multiorgan toxicity greatly limited it from further clinic use. 2-Glucosamine was demonstrated as a potential targeting ligand that could specifical
PMID 25869848

Direct Mitsunobu monoesterification of N-protected tobramycin competes with intramolecular pyrrolidine formation in ester prodrug synthesis.

Quader S1, Boyd SE1, Jenkins ID1, Houston TA2.
Carbohydrate research.Carbohydr Res.2015 May 21;413:16-21. doi: 10.1016/j.carres.2015.04.013. [Epub ahead of print]
Unlike the related aminoglycoside neomycin B, N-protected tobramycin can be selectively esterified at its sole, primary hydroxyl group under Mitsunobu conditions. However, depending on the reaction conditions, the reaction can take a different course with intramolecular cyclization of an N-Boc amine
PMID 26062898

Sub-acute toxicity study of a new aminoglycoside etimicin sulphate in swiss albino mice

Payasi Anurag,Chaudhary Manu,Gupta Ankush [他],DWIVEDI Vivek Kumar
Journal of toxicological sciences 35(4), 479-484, 2010-08-01
… Etimicin sulfate, an ethylization derivative of gentamicin, is a new soluble wide-spectrum synthetic aminoglycoside drug. …
NAID 10026566649

Biosynthetic approach for the production of new aminoglycoside derivative(BIOCHEMICAL ENGINEERING)

Nepal Keshav Kumar,Yoo Jin Cheol,Sohng Jae Kyung
Journal of bioscience and bioengineering 110(1), 109-112, 2010-07-00
… Aminoglycoside antibiotics can be classified into two major groups; … Here, we report a biosynthetic approach for the fusion of spectinomycin and kanamycin biosynthetic gene clusters to yield the new aminoglycoside derivative, oxykanamycinC, in a non-aminoglycoside producing heterologous host. …
NAID 110007681455

High-dose Antibiotic Therapy Is Superior to a 3-Drug Combination of Prostanoids and Lipid A Derivative in Protecting Irradiated Canines

Kumar K. Sree,Srinivasan V.,Toles Raymond E. [他],MINER VENITA L.,JACKSON WILLIAM E.,SEED THOMAS M.
Journal of radiation research 43(4), 361-370, 2002-12-00
… These results indicate that therapy with high doses of intramuscular aminoglycoside antibiotic (gentamicin) and an oral cephalosporin (cephalexin) enhanced survival of irradiated canines. …
NAID 110002334201