English Journal

H2O2 Improves Quality of Radix scutellariae Through Anti-oxidant Effect.

Qi S1, Wu-Lin C1, Hua J2, Ai-Hua Z1, Xiang-Cai M1.
Pharmacognosy magazine.Pharmacogn Mag.2016 Jan-Mar;12(45):84-90. doi: 10.4103/0973-1296.176063.
INTRODUCTION: The correlation between the quality and geographical origin of herbal medicine was traced back to Tang Dynasty in China, more than 1200 years, and the effects of ecological environments on the secondary metabolites such as flavonoids have been confirmed. However, little is known about
PMID 27019566

Diversified glucosinolate metabolism: biosynthesis of hydrogen cyanide and of the hydroxynitrile glucoside alliarinoside in relation to sinigrin metabolism in Alliaria petiolata.

Frisch T1, Motawia MS2, Olsen CE2, Agerbirk N3, Møller BL4, Bjarnholt N5.
Frontiers in plant science.Front Plant Sci.2015 Oct 31;6:926. doi: 10.3389/fpls.2015.00926. eCollection 2015.
Alliaria petiolata (garlic mustard, Brassicaceae) contains the glucosinolate sinigrin as well as alliarinoside, a γ-hydroxynitrile glucoside structurally related to cyanogenic glucosides. Sinigrin may defend this plant against a broad range of enemies, while alliarinoside confers resistance to spec
PMID 26583022

Forces and dynamics of glucose and inhibitor binding to sodium glucose co-transporter SGLT1 studied by single molecule force spectroscopy.

Neundlinger I1, Puntheeranurak T2, Wildling L1, Rankl C3, Wang LX4, Gruber HJ1, Kinne RK5, Hinterdorfer P6.
The Journal of biological chemistry.J Biol Chem.2014 Aug 1;289(31):21673-83. doi: 10.1074/jbc.M113.529875. Epub 2014 Jun 24.
Single molecule force spectroscopy was employed to investigate the dynamics of the sodium glucose co-transporter (SGLT1) upon substrate and inhibitor binding on the single molecule level. CHO cells stably expressing rbSGLT1 were probed by using atomic force microscopy tips carrying either thioglucos
PMID 24962566

Japanese Journal

Genipin Suppresses A23187-Induced Cytotoxicity in Neuro2a Cells

, ,
Biological and Pharmaceutical Bulletin 32(6), 1043-1046, 2009
… Genipin is an iridoid compound and an aglucon of geniposide isolated from Gardenia fructus. …
NAID 130000117184

Blocking Effect of Gynostemma pentaphyllum Makino (GP) on the Point Mutation of Ha-ras Oncogene during Leukoplakia Canceration

, , , , , , , ,
日本口腔粘膜学会雑誌 6(1), 1-6, 2000
… The incidences of point mutation were 22.92% in GP-untreated OL and 7.52% in GP-treated OL (6.25% in the glucoside group, 11.00% in the aglucon group and 5.32% in the C20-OH group). …
NAID 130003673758

NEW ASYMMETRIC SYNTHESES OF (-)-ISOIRIDOMYRMECIN AND (+)-LOGANIN AGLUCON 6-ACETATE UTILIZING C_2-SYMMETRIC DIMETHYL 3,7-DIHYDROXY-CIS-BICYCLO[3.3.0]OCTA-2,6-DIENE-2,6-DICARBOXYLATE

Node Manabu,Araki Mamoru,Tanaka Hiroaki [他],NAKAMURA Daisaku,INOUE Takehisa,NISHIDE Kiyoharu
Chemical & pharmaceutical bulletin 46(4), 736-738, 1998-04-15
The first asymmetric synthesis of (-)-isoiridomyrmecin and formal synthesis of (-)-loganin were done using chiral C_2-symmetric building block dimethyl 3,7-dihydroxy-cis-bicyclo[3.3.0]octa-2,6-diene-2 …
NAID 110003616948

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