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1. von Willebrand因子の生物学および正常機能biology and normal function of von willebrand factor [show details]
… bridging molecule for normal platelet adhesion at sites of vascular injury, and under high shear conditions, it promotes normal platelet aggregation. VWF acts as a carrier for factor… activated factor VIII (fVIIIa) is released from VWF and becomes a fully functional, active cofactor in ongoing thrombin generation, and it can then be inactivated by activated protein C .…
2. 高IgM症候群hyperimmunoglobulin m syndromes [show details]
… the surface of in vitro activated CD4+ lymphocytes can facilitate the diagnosis of X-linked hyper-IgM syndrome and can also be used for carrier detection.… necrosis factor receptor-associated factor (TRAF) molecules and the nuclear factor-kappa-B (NF-κB) signaling pathway,…
3. 化学療法剤の腸管毒性enterotoxicity of chemotherapeutic agents [show details]
… in two of four *13 carriers (50 percent), and in 22 of 27 *9B carriers (82 percent).… mechanisms mentioned above . Ipilimumab is a monoclonal antibody directed against CTLA-4, a molecule on the T-cell surface. Pembrolizumab and nivolumab are monoclonal antibodies directed against the … c.1129-5923C>G) was suggested to activate a splice donor site within intron 10 of the DPYD…
4. 代理母の妊娠gestational carrier pregnancy [show details]
… the gestational carrier . In this review, the term "gestational carrier" will be used to refer to this group of women. Traditional surrogate – In comparison with a gestational carrier above, a traditional …
5. 嚢胞性線維症：キャリアスクリーニングcystic fibrosis carrier screening [show details]
…or Libya, CFTR mutation carrier rates range from 1 in 24 to 1 in 29; for those with ethnic origins in Iran or Iraq, the carrier rate is 1 in 90. Prepregnancy or prenatal carrier screening and prenatal …

English Journal

Interfacial Construction of Plasmonic Nanostructures for the Utilization of the Plasmon-Excited Electrons and Holes.

Zhan C, Wang ZY, Zhang XG, Chen XJ, Huang YF, Hu S, Li JF, Wu DY, Moskovits M, Tian ZQ.
Journal of the American Chemical Society. 2019 May;141(20)8053-8057.
Surface plasmons (SPs) are able to promote chemical reactions through the participation of the energetic charge carriers produced following plasmons decay. Using p-aminothiophenol (PATP) as a probe molecule, we used surface-enhanced Raman spectroscopy to follow the progress of its transformation, in
PMID 31070906

Contribution of Statins towards Periodontal Treatment: A Review.

Petit C, Batool F, Bugueno IM, Schwinté P, Benkirane-Jessel N, Huck O.
Mediators of inflammation. 2019 ;2019()6367402.
The pleiotropic effects of statins have been evaluated to assess their potential benefit in the treatment of various inflammatory and immune-mediated diseases including periodontitis. Herein, the adjunctive use of statins in periodontal therapy , , and in clinical trials was reviewed. Statins act th
PMID 30936777

IL-26, a Cytokine With Roles in Extracellular DNA-Induced Inflammation and Microbial Defense.

Larochette V, Miot C, Poli C, Beaumont E, Roingeard P, Fickenscher H, Jeannin P, Delneste Y.
Frontiers in immunology. 2019 ;10()204.
Interleukin 26 (IL-26) is the most recently identified member of the IL-20 cytokine subfamily, and is a novel mediator of inflammation overexpressed in activated or transformed T cells. Novel properties have recently been assigned to IL-26, owing to its non-conventional cationic, and amphipathic fea
PMID 30809226

Japanese Journal

クラスターデキストリンの体内動態研究 : 生分解性高分子担体としての利用性

田口恭子,金尾義治,田中哲郎
薬剤学 = The archives of practical pharmacy 69(5), 373-383, 2009-09-01
… (CDex, Highly-branched cyclic dextrin) produced from starch is a glucose polymer which has a cyclic structure in the molecule. … Sugar hydroxyl groups of the FCDex were partially activated by periodate oxidation in order to acquire the aldehyde groups to which guest molecules can be bound. …
NAID 10025720785

Pharmacological Interaction of Drugs with Immune Receptors: The p-i Concept

Pichler Werner J,Beeler Andreas,Keller Monika,Lerch Marianne,Posadas Sinforiano,Schmid Daphné,Spanou Zoi,Zawodniak Anna,Gerber Basil
Allergology International 55(1), 17-25, 2006
… Only after covalently binding to an endogenous protein the immune system reacts to this so called hapten-carrier complex, as the larger molecule (protein) is modified, and thus immunogenic for B and T cells. … Thus, the reaction to the drug may not be due to a classical, primary response, but rather be mediated by stimulating existing, pre-activated, peptide-specific T cells that are cross specific for the drug. …
NAID 130004476877

Fabrication and Characteristics of C_<84> Fullerene Field-Effect Transistor

Shibata K,Kubozono Y,Kanbara T,Hosokawa T,Fujiwara A,Ito Y,Shinohara H
Applied Physics Letters 84(14), 2572-2574, 2004-04
… The carrier transport of this FET device can be interpreted as thermally activated hopping transport. … Carrier type (n-channel) and transport mechanism (hopping) reflect the electronic properties of the C_<84> … molecule. …
NAID 120000861162