Tropheryma whipplei

出典: meddic

Tropheryma whipplei
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/12/11 14:18:51」(JST)

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  • [Whipple's disease in an elderly patient with a substantial weight loss and gastrointestinal symptoms.]
  • Jensen MB1, Stawowy M, Christiansen J.
  • Ugeskrift for laeger.Ugeskr Laeger.2014 Dec 15;176(25A). pii: V12120724.
  • Whipple's disease is a multisystemic infection with Tropheryma whipplei often characterised by its gastrointestinal involvement. However, due to the broad spectrum of unspecific symptoms, the diagnosis is often delayed. We report a case of a 70 year-old-man, who presented with extensive weight loss
  • PMID 25497640
  • [Whipple's disease and Tropheryma whipplei infections in internal medicine. When thinking about it? How to treat?].
  • Lagier JC1, Fenollar F1, Raoult D2.
  • La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne.Rev Med Interne.2014 Dec;35(12):801-7. doi: 10.1016/j.revmed.2014.04.016. Epub 2014 Jun 2.
  • Tropheryma whipplei culture and genome sequencing have, thanks to new tools, rationalized both diagnosis and treatment of Whipple's disease. Whipple's disease involves mainly Caucasian male, approximately 50-years-old, suffering from arthralgia, weight loss and diarrhea. A worsening of clinical mani
  • PMID 24933290
  • Gorilla gorilla gorilla gut: a potential reservoir of pathogenic bacteria as revealed using culturomics and molecular tools.
  • Bittar F1, Keita MB1, Lagier JC1, Peeters M2, Delaporte E2, Raoult D1.
  • Scientific reports.Sci Rep.2014 Nov 24;4:7174. doi: 10.1038/srep07174.
  • Wild apes are considered to be the most serious reservoir and source of zoonoses. However, little data are available about the gut microbiota and pathogenic bacteria in gorillas. For this propose, a total of 48 fecal samples obtained from 21 Gorilla gorilla gorilla individuals (as revealed via micro
  • PMID 25417711


  • Whipple Disease Diagnosed with PCR Using Formalin-fixed Paraffin-embedded Specimens of the Intestinal Mucosa
  • Yajima Nobuhisa,Wada Ryuichi,Kimura Sotai,Matsuzaki Yutaka,Chiba Daisuke,Ebina Yoshihito,Ohkusu Kiyofumi,Yagihashi Soroku
  • Internal Medicine 52(2), 219-222, 2013
  • … PCR using FFPE specimens amplified a fragment of 16S rDNA from Tropheryma whipplei. …
  • NAID 130003365854
  • Central Nervous System Relapse of Whipple's Disease
  • Uryu Kiyoaki,Sakai Takashi,Yamamoto Tomonori,Mae Takahito,Willard Yoshie Iwasaki,Sugita Hiroji,Asano Koukichi,Yamashita Kenichi,Harada Hiromasa,Fukuda Kou
  • Internal Medicine 51(15), 2045-2050, 2012
  • Tropheryma whipplei DNA was detected by a polymerase chain reaction in his cerebrospinal fluid. …
  • NAID 130002062266
  • 抗菌化学療法が奏功した Whipple 病の1例
  • 大久保 智恵,藤崎 智明,横田 英介 [他],川崎 啓祐,大城 由美
  • 日本内科学会雑誌 98(10), 2598-2600, 2009-10-10
  • … Whipple病は放線菌近縁のグラム陽性桿菌Tropheryma whipplei(T. …
  • NAID 10025609871


Tropheryma whipplei is rod shaped, a gram-postive bacterium (5). It was finally isolated in eukaryotic cells in the year 2000 and propagated in culture at thirty-seven degrees Celsius, but was believed to resist culturing for a long time ...
Tropheryma whipplei endocarditis differs from classic Whipple disease, which primarily affects the gastrointestinal system. We diagnosed 28 cases of T. whipplei endocarditis in Marseille, France, and compared them with cases ...






Whipple's disease, Whipple disease
腸性脂肪異栄養症 intestinal lipogranulomatosis、特発性脂肪性下痢症 idiopathic steatorrhea、非熱帯性スプルー non-tropical sprue







Tropheryma whipplei