Theiler's virus

出典: meddic

murine poliovirus、Theiler murine encephalomyelitis virus、Theiler virusTheiler's murine encephalomyelitis virusTMEV

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/08/23 14:39:28」(JST)

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  • Theiler's murine encephalomyelitis virus contrasts with encephalomyocarditis and foot-and-mouth disease viruses in its functional utilization of the StopGo non-standard translation mechanism.
  • Loughran G, Libbey JE, Uddowla S, Scallan MF, Ryan MD, Fujinami RS, Rieder E, Atkins JF.SourceDepartment of Biochemistry, Western Gateway Building, University College Cork, Cork, Ireland.
  • The Journal of general virology.J Gen Virol.2013 Feb;94(Pt 2):348-53. doi: 10.1099/vir.0.047571-0. Epub 2012 Oct 24.
  • The picornaviruses' genome consists of a positive-sense ssRNA. Like many picornaviruses, cardioviruses synthesize two distinct polyprotein precursors from adjacent but non-overlapping genome segments. Both the [L-1ABCD-2A] and the [2BC-3ABCD] polyproteins are proteolytically processed to yield matur
  • PMID 23100365
  • Infiltrating Macrophages Are Key to the Development of Seizures following Virus Infection.
  • Cusick MF, Libbey JE, Patel DC, Doty DJ, Fujinami RS.SourceDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • Journal of virology.J Virol.2013 Feb;87(3):1849-60. doi: 10.1128/JVI.02747-12. Epub 2012 Dec 12.
  • Viral infections of the central nervous system (CNS) can trigger an antiviral immune response, which initiates an inflammatory cascade to control viral replication and dissemination. The extent of the proinflammatory response in the CNS and the timing of the release of proinflammatory cytokines can
  • PMID 23236075
  • Chronic social stress impairs virus specific adaptive immunity during acute Theiler's virus infection.
  • Young EE, Vichaya EG, Reusser NM, Cook JL, Steelman AJ, Welsh CJ, Meagher MW.SourceDepartment of Psychology, College of Liberal Arts, Texas A&M University, College Station, TX 77843, United States. Electronic address:
  • Journal of neuroimmunology.J Neuroimmunol.2013 Jan 15;254(1-2):19-27. doi: 10.1016/j.jneuroim.2012.08.014. Epub 2012 Sep 27.
  • Prior exposure to social disruption (SDR) stress exacerbates Theiler's murine encephalomyelitis virus (TMEV) infection, a model of multiple sclerosis. Here we examined the impact of SDR on T cell responses to TMEV infection in SJL mice. SDR impaired viral clearance and exacerbated acute disease. Mor
  • PMID 23021485


  • Microbiological survey of mice (Mus musculus) purchased from commercial pet shops in Kanagawa and Tokyo, Japan
  • , , , , , , ,
  • Experimental Animals advpub(0), 2014
  • … 60.7%), followed by Theiler's murine encephalomyelitis virus (13 mice; … 46.4%), and mouse hepatitis virus (12 mice; …
  • NAID 130004704325
  • Virus-induced expression of retinoic acid inducible gene-I and melanoma differentiation-associated gene 5 in the cochlear sensory epithelium.
  • Hayashi Yushi,Onomoto Koji,Narita Ryo,Yoneyama Mitsutoshi,Kato Hiroki,Nakagawa Takayuki,Ito Juichi,Taura Akiko,Fujita Takashi
  • Microbes and infection 15(8-9), 592-598, 2013-07
  • … We found that RIG-I and MDA5 are expressed in the mouse cochlear sensory epithelium, including Hensen's and Claudius' cells. … Ex vivo viral infection using Theiler's murine encephalomyelitis virus revealed that the virus replicates in these cells and that protein levels of RIG-I and MDA5 are up-regulated. …
  • NAID 120005312147
  • TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection
  • Jin Young-Hee,Kaneyama Tomoki,Kang Min Hyung,Kang Hyun Seok,Koh Chang-Sung,Kim Byung S.
  • … Background: We have previously shown that toll-like receptor 3 (TLR3)-mediated signaling plays an important role in the induction of innate cytokine responses to Theiler's murine encephalomyelitis virus (TMEV) infection. …
  • NAID 120005440191


Figure 2. Theiler's virions. (a) Negative staining of purified BeAn virus particles showing the morphology of featureless virus profiles due to the impermeability of the capsid to the electron dense stain. Scale = 100 μm. (b) Cyroelectron ...
Theiler's virus, a murine picornavirus, causes a persistent infection of macrophage/microglial cells in the central nervous systems of SJL/J mice. Viral replication is restricted in the majority of infected cells, whereas a ...



リンク元Theiler's murine encephalomyelitis virus」「TMEV」「murine poliovirus」「Theiler virus」「タイラーウイルス

Theiler's murine encephalomyelitis virus」


murine poliovirus、Theiler murine encephalomyelitis virus、Theiler virusTheiler's virusTMEV



murine poliovirus、Theiler murine encephalomyelitis virus、Theiler virusTheiler's murine encephalomyelitis virusTheiler's virus

murine poliovirus」


  • マウス・リオウイルス
Theiler murine encephalomyelitis virus、Theiler virusTheiler's murine encephalomyelitis virusTheiler's virusTMEV

Theiler virus」


murine poliovirus、Theiler murine encephalomyelitis virus、Theiler's murine encephalomyelitis virusTheiler's virusTMEV



Theiler's virusTheiler virus



  • v.

WordNet   license wordnet

「to make melodious sounds; "The nightingale was singing"」

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「『歌う』;(…に)歌って聞かせる《+『to』(『for』)+『名』》;(楽器に合わせて)歌う《+『to』+『名』》・〈小鳥・虫などが〉『鳴く』,さえずる / 《文》(…を)詩(歌)にする,(詩(歌)を詠んで)賛美する《+『of』+『名』》・〈小川・風・弾丸・湯沸かし・耳などが〉歌うように鳴る・《米語》自白する;密告する・〈歌〉‘を'歌う・《副詞[句]を伴って》歌って…‘を'(…に)する・…‘を'唱える,詠唱する・《文》…‘を'詩(歌)にする,(詩(歌)に詠んで)賛美する・合唱の集い」

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「deliver by singing; "Sing Christmas carols"」

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「produce tones with the voice; "She was singing while she was cooking"; "My brother sings very well"」


  [★] ウイルス

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「a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"」

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「a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance"」
computer virus

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「(virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein」



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「the 19th letter of the Roman alphabet」

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「sulfurの化学記号 / {略}South[ern]」



single strandsingle-strandsingle-stranded