SRC proteins

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  • Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells.
  • Aksamitiene E, Achanta S, Kolch W, Kholodenko BN, Hoek JB, Kiyatkin A.SourceDepartment of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, 1020 Locust St., Philadelphia, Pennsylvania 19107, USA.
  • Cellular signalling.Cell Signal.2011 Nov;23(11):1794-805. Epub 2011 Jun 25.
  • There is strong evidence that deregulation of prolactin (PRL) signaling contributes to pathogenesis and chemoresistance of breast cancer. Therefore, understanding cross-talk between distinct signal transduction pathways triggered by activation of the prolactin receptor (PRL-R), is essential for eluc
  • PMID 21726627


  • Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells.
  • Ikeda Osamu,Sekine Yuichi,Mizushima Akihiko,Nakasuji Misa,Miyasaka Yuto,Yamamoto Chikako,Muromoto Ryuta,Nanbo Asuka,Oritani Kenji,Yoshimura Akihiko,Matsuda Tadashi
  • The Journal of Biological Chemistry 285(49), 38093-38103, 2010-12-06
  • … Signal transducing adaptor protein-2 (STAP-2) is a recently identified adaptor protein, which contains pleckstrin homology (PH) and Src homology 2 (SH2)-like domains, as well as a signal transducer and an activator of transcription 3 (STAT3)-binding motif in its C-terminal region. …
  • NAID 120002646845


The Src protein was the first TYROSINE KINASE to be discovered. ... is the recognition of PHOSPHOTYROSINE by small protein modules known as SH2 domains (Src homology domains) which were first discovered in the Src proteins. ...


Oncogene proteins (Oncogene Products Regulation of TGF-β1-induced pro Structure and activation of SRC proteins Transmembrane adaptor proteins: organizers CHAPTER 9 - SIGNAL TRANSDUCTIONExamples of Src homology 2 (SH2)-domain



  [★] 蛋白質

WordNet   license wordnet

「any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"」

PrepTutorEJDIC   license prepejdic




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「the 19th letter of the Roman alphabet」

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「sulfurの化学記号 / {略}South[ern]」