WordNet
- the 18th letter of the Roman alphabet (同)r
- ancient Egyptian sun god with the head of a hawk; a universal creator; he merged with the god Amen as Amen-Ra to become the king of the gods (同)Re
PrepTutorEJDIC
- resistance / 17歳以下父兄同伴映画の表示 / rook
- radiumの化学記号
UpToDate Contents
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- 1. 炎症性乳癌：病理および分子学的病因 inflammatory breast cancer pathology and molecular pathogenesis
- 2. 網膜色素変性症：臨床症状および診断 retinitis pigmentosa clinical presentation and diagnosis
- 3. ペプチドホルモンのシグナル伝達および調節 peptide hormone signal transduction and regulation
- 4. 糸球体足細胞のバイオロジー biology of glomerular podocytes
- 5. ネフロン癆の遺伝学および病因 genetics and pathogenesis of nephronophthisis
English Journal
- Intrinsic protein fluorescence assays for GEF, GAP and post-translational modifications of small GTPases.
- Goody PR1.
- Analytical biochemistry.Anal Biochem.2016 Dec 15;515:22-25. doi: 10.1016/j.ab.2016.09.019. Epub 2016 Sep 22.
- Evidence and arguments are summarized that suggest that intrinsic (tryptophan) protein fluorescence provides an excellent and convenient signal for monitoring both GEF (guanine nucleotide exchange factor) and GAP (GTPase activating protein) activity of a large number of small GTPases. In addition, p
- PMID 27665678
- Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke.
- Lucitti JL1, Sealock R1, Buckley BK1, Zhang H1, Xiao L1, Dudley AC1, Faber JE2.
- Stroke.Stroke.2016 Dec;47(12):3022-3031. Epub 2016 Nov 3.
- BACKGROUND AND PURPOSE: The extent (number and diameter) of collateral vessels varies widely and is a major determinant, along with arteriogenesis (collateral remodeling), of variation in severity of tissue injury after large artery occlusion. Differences in genetic background underlie the majority
- PMID 27811335
- Multiple crosstalk between TOR and the cell integrity MAPK signaling pathway in fission yeast.
- Madrid M1, Vázquez-Marín B1, Franco A1, Soto T1, Vicente-Soler J1, Gacto M1, Cansado J1.
- Scientific reports.Sci Rep.2016 Nov 23;6:37515. doi: 10.1038/srep37515.
- In eukaryotic cells, the highly conserved Target of Rapamycin (TOR) and the Mitogen Activated Protein Kinase (MAPK) signaling pathways elicit adaptive responses to extra- and intracellular conditions by regulating essential cellular functions. However, the nature of the functional relationships betw
- PMID 27876895
Japanese Journal
- An early endosome regulator, Rab5b, is an LRRK2 kinase substrate
- Yun Hye Jin,Kim Hyejung,Ga Inhwa [他]
- The journal of biochemistry 157(6), 485-495, 2015-06
- NAID 40020489265
- Expression and intracellular localization of TBC1D9, a Rab GTPase-accelerating protein, in mice testes
- NAKAMURA Yutaka,ASANO Atsushi,HOSAKA Yoshinao,TAKEUCHI Takashi,IWANAGA Toshihiko,YAMANO Yoshiaki
- Experimental Animals advpub(0), 2015
- … TBC family proteins work as Rab GTPase accelerating proteins (GAPs), which negatively regulate Rab proteins, to mediate membrane trafficking. … In this study, we analyzed the expression of a Rab GAP, TBC1D9, in mouse organs and the intracellular localization of the gene products. … Compartments that were positive for the constitutive active mutants of Rab7 and Rab9 were also positive for TBC1D9 isoform 1. …
- NAID 130005083900
- GTP- and GDP-Dependent Rab27a Effectors in Pancreatic Beta-Cells
- Yamaoka Mami,Ishizaki Toshimasa,Kimura Toshihide
- Biological and Pharmaceutical Bulletin 38(5), 663-668, 2015
- … Conventionally, only the guanosine 5′-triphosphate (GTP)-bound small GTPase interacts with effector proteins, and the resulting downstream signals control specific cellular functions. … The Rab family small GTPase Rab27a is highly expressed in some secretory cells and is involved in the control of membrane traffic. … The present study reviews recent progress in our understanding of the roles of Rab27a and its effectors in pancreatic beta-cells. …
- NAID 130005068105
Related Links
- 系統樹から５つのサブファミリー、Ras、Rho、Rab、Arf、Ranに分けられる。それぞれに 特徴的な機能を果たすことが知られている。 Rasファミリー：チロシンキナーゼ型受容体 からのシグナル伝達経路にあり、細胞増殖調節に関与する。Ras, Rapについて特に ...
- Abstract. Intracellular membrane traffic defines a complex network of pathways that connects many of the membrane-bound organelles of eukaryotic cells. Although each pathway is governed by its own set of factors, they all contain Rab ...
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★リンクテーブル★
| リンク元 | 「Rab GTP-binding protein」「GTPアーゼRab」 |
| 関連記事 | 「R」「GTPase」 |
「Rab GTP-binding protein」
「GTPアーゼRab」
「R」