Philadelphia-positive myeloid leukemia

出典: meddic

フィラデルフィア陽性骨髄性白血病

chronic granulocytic leukemiachronic myelocytic leukemiachronic myelogenous leukemiachronic myeloid leukemiaPhiladelphia-negative myeloid leukemia

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英文文献

  • Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase.
  • Mologni L, Redaelli S, Morandi A, Plaza-Menacho I, Gambacorti-Passerini C.SourceDept. of Health Sciences, University of Milano-Bicocca, via Cadore 48, 20900 Monza, Italy. Electronic address: luca.mologni@unimib.it.
  • Molecular and cellular endocrinology.Mol Cell Endocrinol.2013 Sep 5;377(1-2):1-6. doi: 10.1016/j.mce.2013.06.025. Epub 2013 Jun 27.
  • RET kinase is aberrantly activated in thyroid cancers and in rare cases of lung and colon cancer, and has been validated as a molecular target in these tumors. Vandetanib was recently approved for the treatment of medullary thyroid cancer. However, vandetanib is ineffective in vitro against RET muta
  • PMID 23811235
  • Alantolactone induces apoptosis in chronic myelogenous leukemia sensitive or resistant to imatinib through NF-κB inhibition and Bcr/Abl protein deletion.
  • Wei W, Huang H, Zhao S, Liu W, Liu CX, Chen L, Li JM, Wu YL, Yan H.SourceDepartment of Hematology, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, No. 197, Ruijin Er Road, Shanghai, 200025, China.
  • Apoptosis : an international journal on programmed cell death.Apoptosis.2013 Sep;18(9):1060-70. doi: 10.1007/s10495-013-0854-2.
  • Alantolactone, an allergenic sesquiterpene lactone, has recently been found to have significant antitumor effects on malignant tumor cells. Here, we investigated the potential effect of alantolactone on Bcr/Abl(+) imatinib-sensitive and -resistant cells. Alantolactone treatment resulted in obvious a
  • PMID 23613107
  • Effects of ketoconazole on the pharmacokinetics of ponatinib in healthy subjects.
  • Narasimhan NI, Dorer DJ, Niland K, Haluska F, Sonnichsen D.SourceARIAD Pharmaceuticals, Inc., Cambridge, MA, USA.
  • Journal of clinical pharmacology.J Clin Pharmacol.2013 Sep;53(9):974-81. doi: 10.1002/jcph.109. Epub 2013 Jun 25.
  • Ponatinib is a BCR-ABL tyrosine kinase inhibitor (TKI) approved for the treatment of chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia in patients resistant or intolerant to prior TKIs. In vitro studies suggested that metabolism of ponatinib is partially medi
  • PMID 23801357

和文文献

  • 臍帯血移植後に生着不全となったがPh染色体の消失を認めたPh染色体陽性急性骨髄性白血病
  • 浜田 泰子,中村 恭子,田近 賢二 [他],檀 和夫
  • 臨床血液 52(2), 58-62, 2011-02-28
  • Philadelphia染色体(Ph)陽性急性骨髄性白血病(Ph+AML)と診断し,imatinib併用化学療法後,骨髄非破壊的臍帯血移植を施行した。 …
  • NAID 10029424249
  • Can We Distinguish Chronic Myeloid Leukemia Presenting in the Lymphoblastic Phase from de novo Philadelphia-Positive Acute Lymphoid Leukemia?
  • イマチニブ時代における小児Ph陽性慢性骨髄性白血病の治療戦略
  • 村松 秀城,小島 勢二,嶋田 博之
  • 日本小児血液学会雑誌 23(2), 101-106, 2009-04-30
  • NAID 10029310366

関連リンク

3 Feb 2012 ... Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann Intern Med 138 (10): 819-30, 2003. [PUBMED Abstract]; Goldman JM, Melo JV: Chronic myeloid leukemia--advances in ...

関連画像

Leukemia Chronic Myeloid CML Symptoms  Philadelphia chromosome–positive B Positive Acute Myeloid Leukemia: Results Philadelphia-positive chronic myeloid positive chronic myeloid leukemia (Ph+ CMLTasigna Chronic and Accelerated Phase in


★リンクテーブル★
先読みchronic myelocytic leukemia」「chronic myelogenous leukemia」「chronic myeloid leukemia」「chronic granulocytic leukemia
リンク元Philadelphia-negative myeloid leukemia」「フィラデルフィア陽性骨髄性白血病
関連記事positive」「Philadelphia」「myeloid」「leukemia」「myelo

chronic myelocytic leukemia」

  [★] 慢性骨髄性白血病 CML


chronic myelogenous leukemia」

  [★] 慢性骨髄性白血病 CML


chronic myeloid leukemia」

  [★] 慢性骨髄性白血病 CML


chronic granulocytic leukemia」

  [★]

chronic myeloid leukemia


Philadelphia-negative myeloid leukemia」

  [★]

フィラデルフィア陰性骨髄性白血病

chronic granulocytic leukemiachronic myelocytic leukemiachronic myelogenous leukemiachronic myeloid leukemiaPhiladelphia-positive myeloid leukemia


フィラデルフィア陽性骨髄性白血病」

  [★]

Philadelphia-positive myeloid leukemia
慢性骨髄性白血病慢性顆粒球性白血病フィラデルフィア陰性骨髄性白血病


positive」

  [★]

  • adj.
  • 陽性の、正の、積極的な、ポジティブな
activeactivelyaggressiveoffensivepositivelypositivity

WordNet   license wordnet

「reckoned, situated or tending in the direction which naturally or arbitrarily is taken to indicate increase or progress or onward motion; "positive increase in graduating students"」

WordNet   license wordnet

「a film showing a photographic image whose tones correspond to those of the original subject」

WordNet   license wordnet

「the primary form of an adjective or adverb; denotes a quality without qualification, comparison, or relation to increase or diminution」
positive degree

PrepTutorEJDIC   license prepejdic

「『肯定した,同意の』 / 『実際的な,』積極的な,建設的な / 《補語にのみ用いて》『確信のある』,自信のある / (事が)疑問の余地がない,明確な;(言葉が)はっきりした / 《名詞の前にのみ用いて》《話》全くの,文字どおりの / (生体の反応が)陽性の / (数が)正の,プラスの;(気電が)陽の;(写真で)陽画の / (形容詞・副詞の比較変化で)原級の / 明確(明白)なもの / (形容詞・副詞の)原級 / (写真の)陽画,ポジ / (数学で)正数」

WordNet   license wordnet

「indicating existence or presence of a suspected condition or pathogen; "a positive pregnancy test"」
confirming

WordNet   license wordnet

「having a positive charge; "protons are positive"」
electropositive, positively charged

WordNet   license wordnet

「formally laid down or imposed; "positive laws"」
prescribed

WordNet   license wordnet

「characterized by or displaying affirmation or acceptance or certainty etc.; "a positive attitude"; "the reviews were all positive"; "a positive benefit"; "a positive demand"」

WordNet   license wordnet

「greater than zero; "positive numbers"」


Philadelphia」

  [★]

WordNet   license wordnet

「the largest city in Pennsylvania; located in the southeastern part of the state on the Delaware river; site of Independence Hall where the Declaration of Independence and the Constitution were signed; site of the University of Pennsylvania」
City of Brotherly Love

PrepTutorEJDIC   license prepejdic

「『フィラデルフィア』(米国Pennsylvania州の大都市;1776年7月4日,米国独立宣言の行われた所)」

myeloid」

  [★]

  • adj.
BMbone marrowmyelomyelocyticmyelogenous

WordNet   license wordnet

「of or relating to the spinal cord」

WordNet   license wordnet

「of or relating to bone marrow」


leukemia」

  [★] 白血病

WordNet   license wordnet

「malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer」
leukaemia, leucaemia, cancer of the blood

PrepTutorEJDIC   license prepejdic

「白血病」


myelo」

  [★]

  • comb form
  • ex.




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