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peroxisome proliferator-activated receptor alpha、PPARalpha

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/04/27 22:14:27」(JST)

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  • Angiotensin-I converting enzyme inhibitory peptides from antihypertensive skate (Okamejei kenojei) skin gelatin hydrolysate in spontaneously hypertensive rats.
  • Ngo DH1, Kang KH1, Ryu B2, Vo TS1, Jung WK3, Byun HG4, Kim SK5.
  • Food chemistry.Food Chem.2015 May 1;174:37-43. doi: 10.1016/j.foodchem.2014.11.013. Epub 2014 Nov 8.
  • The aim of this study was to investigate antihypertensive effect of bioactive peptides from skate (Okamejei kenojei) skin gelatin. The Alcalase/protease gelatin hydrolysate below 1kDa (SAP) exhibited the highest angiotensin-I converting enzyme (ACE) inhibition compared to other hydrolysates. SAP can
  • PMID 25529649
  • Involvement of PPAR receptors in the anticonvulsant effects of a cannabinoid agonist, WIN 55,212-2.
  • Payandemehr B1, Ebrahimi A1, Gholizadeh R2, Rahimian R3, Varastehmoradi B2, Gooshe M2, Aghaei HN4, Mousavizadeh K5, Dehpour AR2.
  • Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2015 Mar 3;57:140-5. doi: 10.1016/j.pnpbp.2014.11.005. Epub 2014 Nov 13.
  • Cannabinoid and PPAR receptors show well established interactions in a set of physiological effects. Regarding the seizure-modulating properties of both classes of receptors, the present study aimed to evaluate the roles of the PPAR-gamma, PPAR-alpha and CB1 receptors on the anticonvulsant effects o
  • PMID 25448777
  • Fructose supplementation impairs rat liver autophagy through mTORC activation without inducing endoplasmic reticulum stress.
  • Baena M1, Sangüesa G1, Hutter N1, Sánchez RM2, Roglans N2, Laguna JC2, Alegret M3.
  • Biochimica et biophysica acta.Biochim Biophys Acta.2015 Feb;1851(2):107-16. doi: 10.1016/j.bbalip.2014.11.003. Epub 2014 Nov 9.
  • Supplementation with 10% liquid fructose to female rats for 2weeks caused hepatic steatosis through increased lipogenesis and reduced peroxisome proliferator activated receptor (PPAR) α activity and fatty acid catabolism, together with increased expression of the spliced form of X-binding protein-1
  • PMID 25463011


  • ER stress response, peroxisome proliferation, mitochondrial unfolded protein response and Golgi stress response.
  • Yoshida Hiderou,吉田 秀郎
  • IUBMB life 61(9), 871-879, 2009-09
  • … The proliferation of the peroxisome is regulated by the PPAR alpha pathway, whereas the abundance of mitochondria appears to be regulated by mitochondrial retrograde signaling and the mitochondrial unfolded protein response. …
  • NAID 120001700385
  • No Modifying Effect of Antioxidant N-Acetyl-L-Cysteine on Fenofibrate-induced Hepatocarcinogenesis in Rats
  • Nishimura Jihei,Dewa Yasuaki,Jin Meilan,Saegusa Yukie,Kawai Masaomi,Kemmochi Sayaka,Shimamoto Keisuke,Harada Tomoaki,Itoh Tadashi,Shima Tomomi,Shibutani Makoto,Mitsumori Kunitoshi
  • Journal of Toxicologic Pathology 22(4), 255-261, 2009
  • … To clarify the modifying effect of N-Acetyl-L-Cysteine (NAC), which has antioxidative ability, on hepatocarcinogenesis promoted by fenofibrate (FF), a peroxisome proliferator-activated receptor (PPAR) alpha agonist, male F344/N rats were administered a single intraperitoneal injection of N-diethylnitrosamine (DEN) as an initiator followed by administration of a diet containing 3,000 ppm of FF for 16 weeks. …
  • NAID 130000151276
  • Deletion of angiotensin II type I receptor reduces hepatic steatosis
  • Nabeshima Yoshitaka,Tazuma Susumu,Kanno Keishi,Hyogo Hideyuki,Chayama Kazuaki,ナベシマ ヨシタカ,タヅマ ススム カンノ ケイシ,ヒョウゴ ヒデユキ,チャヤマ カズアキ,鍋島 由宝,田妻 進,菅野 啓司,兵庫 秀幸,茶山 一彰
  • Journal of Hepatology 50(6), 1226-1235, 2009
  • … These effects were generally explained by selective peroxisome proliferator-activated receptor (PPAR) gamma modulating properties of ARBs, independent of their AT1R blocking actions. … Results: Compared to wild-type (WT), A T1a(-/-) mice fed methionine-choline deficient (MCD) diet resulted in negligible lipid accumulation in the liver with marked induction of PPAR alpha mRNA. …
  • NAID 120001700483


PPARαとは peroxisome proliferator-activated receptor-α(ペルオキシゾーム増殖剤応答性受容体-α)で転写因子PPARの1つ。 多く発現する臓器・組織 肝臓 腎臓 心臓 骨格 […]
1. Pharm Res. 2004 Sep;21(9):1531-8. Peroxisome proliferator-activated receptor (PPAR)-alpha: a pharmacological target with a promising future. van Raalte DH(1), Li M, Pritchard PH, Wasan KM. Author ...


Ppar Alpha (PPARalpha) off ppar alpha the other antiviral protein ppars ppar alpha ppar delta and ppar gammaPpar Alpha (PPARalpha)Peroxisome proliferator-activated receptorPpar Alpha (PPARalpha)

リンク元PPARα」「PPAR-α」「ペルオキシソーム増殖剤活性化受容体α」「ペルオキシソーム増殖因子活性化受容体α」「peroxisome proliferator-activated receptor alpha



  • PPARalpha、PPAR-alpha



  • PPAR-alpha



peroxisome proliferator-activated receptor alphaPPAR-alpha




peroxisome proliferator-activated receptor alpha」








WordNet   license wordnet

「first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"」

WordNet   license wordnet

「the 1st letter of the Greek alphabet」

WordNet   license wordnet

「the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations」

PrepTutorEJDIC   license prepejdic

「アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)」

WordNet   license wordnet

「early testing stage of a software or hardware product; "alpha version"」



peroxisome proliferator-activated receptor
peroxisome proliferator activated receptor-7
  • 転写因子。核内受容体。





WordNet   license wordnet

「any high mountain」

PrepTutorEJDIC   license prepejdic




primary progressive aphasia
pure pulmonary atresia
pure pulmonary atresia