N-acylsphingosine galactosyltransferase

N-アシルスフィンゴシン・ガラクトシルトランスフェラーゼ

WordNet

1. the 14th letter of the Roman alphabet (同)n

PrepTutorEJDIC

1. nitrogenの化学記号
2. neodymiumの化学記号

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/10/24 15:49:20」(JST)

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N-acylsphingosine galactosyltransferase
Identifiers
EC number	2.4.1.47
CAS number	37277-56-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a N-acylsphingosine galactosyltransferase (EC 2.4.1.47) is an enzyme that catalyzes the chemical reaction

UDP-galactose + N-acylsphingosine UDP + D-galactosylceramide

Thus, the two substrates of this enzyme are UDP-galactose and N-acylsphingosine, whereas its two products are UDP and D-galactosylceramide.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:N-acylsphingosine D-galactosyltransferase. Other names in common use include UDP galactose-N-acylsphingosine galactosyltransferase, and uridine diphosphogalactose-acylsphingosine galactosyltransferase. This enzyme participates in sphingolipid metabolism.

References

• Fujino Y, Nakano M (1969). "Enzymic synthesis of cerebroside from ceramide and uridine diphosphate galactose". Biochem. J. 113 (3): 573–5. PMC 1184705. PMID 5807218. 

UpToDate Contents

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English Journal

• The neuroprotective effect of pyrroloquinoline quinone on traumatic brain injury.

• Zhang L, Liu J, Cheng C, Yuan Y, Yu B, Shen A, Yan M.SourceJiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, Jiangsu Province, PR China.
• Journal of neurotrauma.J Neurotrauma.2012 Mar 20;29(5):851-64. Epub 2011 Dec 20.
• Pyrroloquinoline quinone (PQQ) is a water-soluble, anionic, quinonoid substance that has been established as an essential nutrient in animals. Owing to the inherent properties of PQQ as an antioxidant and redox modulator in various systems, PQQ is expected to be used in pharmacological applications
• PMID 22040225

• Myelination in the absence of UDP-galactose:ceramide galactosyl-transferase and fatty acid 2 -hydroxylase.

• Meixner M, Jungnickel J, Grothe C, Gieselmann V, Eckhardt M.SourceInstitute of Biochemistry and Molecular Biology, University of Bonn, Germany.
• BMC neuroscience.BMC Neurosci.2011 Mar 2;12:22.
• BACKGROUND: The sphingolipids galactosylceramide (GalCer) and sulfatide are major myelin components and are thought to play important roles in myelin function. The importance of GalCer and sulfatide has been validated using UDP-galactose:ceramide galactosyltransferase-deficient (Cgt-/-) mice, which
• PMID 21366909

Related Links

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• N-Acylsphingosine Galactosyltransferase - RightDiagnosis.com

N-Acylsphingosine Galactosyltransferase information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Introduction: N-Acylsphingosine Galactosyltransferase Description of N ...

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★リンクテーブル★

リンク元	「N-アシルスフィンゴシン・ガラクトシルトランスフェラーゼ」
関連記事	「galactosyltransferase」「n」「N」「acylsphingosine」「Nd」

「N-アシルスフィンゴシン・ガラクトシルトランスフェラーゼ」

　　[★]

英

N-acylsphingosine galactosyltransferase

「galactosyltransferase」

　　[★]

ガラクトース転移酵素、ガラクトシルトランスフェラーゼ、ガラクトシル基転移酵素

「n」

　　[★]

• n.

• 例数

関

number of experiment、sample size

• pの前の[n]はmと記載する。synptom→symptom

「N」

　　[★]

• アスパラギン asparagine
• 窒素(原子、分子)

　 　

「acylsphingosine」

　　[★]

アシルスフィンゴシン

「Nd」

　　[★] ネオジム neodymium