- 関
- interleukin-15 receptor
WordNet
- the 9th letter of the Roman alphabet (同)i
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
PrepTutorEJDIC
- 『私は』私が
- iodineの化学記号
- =sense organ / 受信装置
- Illinois
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/10 14:47:12」(JST)
[Wiki en表示]
| interleukin 15 receptor, alpha |
|
| Identifiers |
| Symbol |
IL15RA |
| Entrez |
3601 |
| HUGO |
5978 |
| OMIM |
601070 |
| RefSeq |
NM_172200 |
| UniProt |
Q13261 |
| Other data |
| Locus |
Chr. 10 p15-10p14 |
| interleukin 2 receptor, beta |
|
| Identifiers |
| Symbol |
IL2RB |
| Alt. symbols |
CD122 |
| Entrez |
3560 |
| HUGO |
6009 |
| OMIM |
146710 |
| RefSeq |
NM_000878 |
| UniProt |
P14784 |
| Other data |
| Locus |
Chr. 22 q13 |
| interleukin 2 receptor, gamma (severe combined immunodeficiency) |
|
| Identifiers |
| Symbol |
IL2RG |
| Alt. symbols |
SCIDX1, IMD4 |
| Entrez |
3561 |
| HUGO |
6010 |
| OMIM |
308380 |
| RefSeq |
NM_000206 |
| Other data |
| Locus |
Chr. X q13 |
Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. It consists of an interleukin 15 receptor, alpha subunit and shares common beta and gamma subunits with the IL-2 receptor.[1]
References
- ^ Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA (1995). "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. Biol. Chem. 270 (50): 29862–9. doi:10.1074/jbc.270.50.29862. PMID 8530383.
External links
- Receptors,+Interleukin-15 at the US National Library of Medicine Medical Subject Headings (MeSH)
|
Cytokine receptors
|
|
Chemokine receptor
(GPCRs) |
| CC |
- CCR1/CCRL1
- CCR2
- CCRL2
- CCR3
- CCR4
- CCR5
- CCR6
- CCR7
- CCR8
- CCR9
- CCR10
|
|
| CXC |
- IL-8
- CXCR3
- CXCR4
- CXCR5
- CXCR6
- CXCR7
|
|
| Other |
|
|
|
| TNF receptor |
| 1-10 |
- TNFRSF1 (CD120)
- TNFRSF1A (CD120a)
- TNFRSF1B (CD120b)
- TNFRSF3 (Lymphotoxin beta receptor)
- TNFRSF4 (CD134)
- TNFRSF5 (CD40)
- TNFRSF6 (FAS)
- TNFRSF6B
- TNFRSF7 (CD27)
- TNFRSF8 (CD30)
- TNFRSF9 (CD137)
|
|
| 11-20 |
- TNFRSF10A (CD261)
- TNFRSF10B (CD262)
- TNFRSF10C (CD263)
- TNFRSF10D (CD264)
- TNFRSF11A (CD265/RANK)
- TNFRSF11B (Osteoprotegerin)
- TNFRSF12A (CD266)
- TNFRSF13B (CD267)
- TNFRSF13C
- TNFRSF14 (CD268)
- TNFRSF16 (Nerve growth factor receptor)
- TNFRSF17 (CD269)
- TNFRSF18
- TNFRSF19
|
|
| 21-25 |
- TNFRSF21
- TNFRSF25
- TNFRSF27
|
|
|
| JAK-STAT |
| Type I |
| γ-chain |
- Interleukin receptors
- IL2R/IL2RA/IL2RB/IL15R
- IL4R/IL13R/IL13RA1/IL13RA2
- IL7R/IL7RA
- IL9R
- IL21R
|
|
| β-chain |
- Interleukin receptors
- GM-CSF
|
|
| gp130 |
- Interleukin receptors
- IL6RA
- 11/IL11RA
- 27/IL27RA
- OSMR
- LIFR
- CNTFR
|
|
| IL12RB1 |
- Interleukin receptors
- IL12R/IL12RB1/IL12RB2
- IL23R23
|
|
| Other |
- hormone receptor: GH
- prolactin
|
|
|
| Type II |
- Interleukin receptors
- IL10R/IL10RA/IL10RB/IL22R/IL22RA2
- IL20R/IL20RA/IL20RB
- IL28R
- Interferon receptors
- -α/β/IFNAR1/IFNAR2
- -γ/IFNGR1/IFNGR2
|
|
|
| Ig superfamily |
- CSF1
- KIT
- IL1
- IL18R/IL18R1
|
|
| IL-17 family |
- IL-17
- IL17RA
- IL17RB
- IL17RC
- IL17RD
- IL17RE
|
|
| S/T |
|
|
|
B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)
|
|
UpToDate Contents
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English Journal
- Resveratrol sensitized leukemia stem cell-like KG-1a cells to cytokine-induced killer cells-mediated cytolysis through NKG2D ligands and TRAIL receptors.
- Hu L, Cao D, Li Y, He Y, Guo K.SourceDepartment of Hematology; Zhujiang Hospital; Southern Medical University; Guangzhou, China; These authors have contributed equally to this work.
- Cancer biology & therapy.Cancer Biol Ther.2012 May 1;13(7). [Epub ahead of print]
- Human promyeloblastic leukemia KG-1a cells exhibit many characteristics similar to leukemia stem cells, which are resistant to chemotherapeutic drugs and hyposensitive to cytotoxic cells. Resveratrol (RES), as a member of plant polyphenols, has gained considerable attention due to its ability to pre
- PMID 22406996
- Densely granulated murine NK cells eradicate large solid tumors.
- Liu RB, Engels B, Arina A, Schreiber K, Hyjek E, Schietinger A, Binder DC, Butz E, Krausz T, Rowley DA, Jabri B, Schreiber H.SourceAuthors' Affiliations: Committee on Immunology, Department of Pathology, Committee on Cancer Biology, Department of Medicine, The University of Chicago, Chicago, Illinois; and Inflammation Department, AMGEN, Seattle, Washington.
- Cancer research.Cancer Res.2012 Apr 15;72(8):1964-74. Epub 2012 Feb 28.
- Natural killer (NK) cells inhibit early stages of tumor formation, recurrence, and metastasis. Here, we show that NK cells can also eradicate large solid tumors. Eradication depended on the massive infiltration of proliferating NK cells due to interleukin 15 (IL-15) released and presented by the can
- PMID 22374983
Japanese Journal
- Prolonged recurrence-free survival following OK432-stimulated dendritic cell transfer into hepatocellular carcinoma during transarterial embolization
- Nakamoto Yasunari,Mizukoshi Eishiro,Kitahara Masaaki,Arihara Fumitaka,Sakai Yoshio,Kakinoki Kaheita,Fujita Yui,Marukawa Yohei,Arai Kuniaki,Yamashita Tatsuya,Mukaida Naofumi,Matsushima Kouji,Matsui Osamu,Kaneko Shuichi
- Clinical and Experimental Immunology 163(2), 165-177, 2011-02-00
- … DCs were derived from peripheral blood monocytes of patients with hepatitis C virus-related cirrhosis and HCC in the presence of interleukin (IL)-4 and granulocyte-macrophage colony-stimulating factor and stimulated with 0.1 KE/ml OK432 for 2 days. … OK432 stimulation of immature DCs promoted their maturation towards cells with activated phenotypes, high expression of a homing receptor, fairly well-preserved phagocytic capacity, greatly enhanced cytokine production and effective tumoricidal activity. …
- NAID 120003141443
- (2)血管新生と脱落膜化における性ステロイドホルモンによる調節機構の解明(シンポジウム2「子宮内膜の機能調節とその病態」,第62回日本産科婦人科学会・学術講演会)
- 岡田 英孝
- 日本産科婦人科學會雜誌 62(11), 2337-2349, 2010-11-01
- … Several mediators regulate angiogenesis, including, vascular endothelial growth factor (VEGF), soluble VEGF receptor 1 (sVEGFR-1) as a VEGF antagonist, and stromal cell-derived factor 1 (SDF-1/CXCL12). … Firstly, we determined whether E can regulate VEGF and sVEGFR-1 as a VEGF antagonist, and SDF-1 in human endometrial stromal cells (ESCs) and to determine whether SDF-1 can induce the proliferation mediated by its receptor (CXCR4) in the human endometrium. …
- NAID 110007880688
Related Links
- The cytokine interleukin-15 (IL-15) has a key role in promoting survival, proliferation and activation of natural killer (NK) and CD8+ T cells. Despite its func ... IL-15 contains two disulfide bonds at positions 42 Cys– 88 Cys (which is ...
- Data suggest that the Interleukin (IL)-15 and interleukin 15 receptor alpha (IL-15.IL-15Ralpha) complex cleaved from presenting cells allows responding cells to internalize, store and use IL-15.IL-15Ralpha complex for their own ...
★リンクテーブル★
[★]
- 英
- interleukin-15 receptor、IL-15 receptor
- 関
- IL-15受容体、IL-15レセプター
[★]
- 英
- IL-15 receptor
- 関
- インターロイキン15受容体、IL-15レセプター
[★]
- 英
- IL-15 receptor
- 関
- インターロイキン15受容体、IL-15受容体
[★]
インターロイキン15受容体
- 関
- IL-15 receptor
[★]
[★]