interleukin-15 receptor

インターロイキン15受容体

関

IL-15 receptor

WordNet

1. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
2. any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system

PrepTutorEJDIC

1. =sense organ / 受信装置

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/21 22:54:11」(JST)

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[Wiki en表示]

interleukin 15 receptor, alpha
Identifiers
Symbol	IL15RA
Entrez	3601
HUGO	5978
OMIM	601070
RefSeq	NM_172200
UniProt	Q13261
Other data
Locus	Chr. 10 p15-10p14

interleukin 2 receptor, beta
Identifiers
Symbol	IL2RB
Alt. symbols	CD122
Entrez	3560
HUGO	6009
OMIM	146710
RefSeq	NM_000878
UniProt	P14784
Other data
Locus	Chr. 22 q13

interleukin 2 receptor, gamma (severe combined immunodeficiency)
Identifiers
Symbol	IL2RG
Alt. symbols	SCIDX1, IMD4
Entrez	3561
HUGO	6010
OMIM	308380
RefSeq	NM_000206
Other data
Locus	Chr. X q13

Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. It consists of an interleukin 15 receptor, alpha subunit and shares common beta and gamma subunits with the IL-2 receptor.

References

External links

• Receptors, Interleukin-15 at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

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• 1. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
• 2. リウマチ性疾患のマネージメントに用いる生物学的製剤とキナーゼ阻害薬の概要 overview of biologic agents and kinase inhibitors in the rheumatic diseases
• 3. サルコイドーシスの病因 pathogenesis of sarcoidosis
• 4. リウマチ結節 rheumatoid nodules
• 5. リウマチ性疾患におけるサイトカインの役割 role of cytokines in rheumatic diseases

English Journal

• IL15RA is required for osteoblast function and bone mineralization.

• Loro E1, Ramaswamy G2, Chandra A3, Tseng WJ2, Mishra MK1, Shore EM4, Khurana TS5.
• Bone.Bone.2017 Oct;103:20-30. doi: 10.1016/j.bone.2017.06.003. Epub 2017 Jun 6.
• PMID 28602725

• CD4 effector T cell differentiation is controlled by IL-15 that is expressed and presented in trans.

• Waickman AT1, Ligons DL1, Hwang S1, Park JY1, Lazarevic V1, Sato N2, Hong C3, Park JH4.
• Cytokine.Cytokine.2017 Aug 11. pii: S1043-4666(17)30237-5. doi: 10.1016/j.cyto.2017.08.004. [Epub ahead of print]
• PMID 28807496

• In Vitro Culture with Interleukin-15 Leads to Expression of Activating Receptors and Recovery of Natural Killer Cell Function in Acute Myeloid Leukemia Patients.

• Sanchez-Correa B1, Bergua JM2, Pera A3,4, Campos C3, Arcos MJ2, Bañas H2, Duran E5, Solana R1,3, Tarazona R1.
• Frontiers in immunology.Front Immunol.2017 Aug 7;8:931. doi: 10.3389/fimmu.2017.00931. eCollection 2017.
• PMID 28824651

Japanese Journal

• IL-15とNK細胞の発生・分化・ホメオスタシス

• 瀧 伸介
• 臨床免疫・アレルギー科 59(1), 140-146, 2013-01
• NAID 40019567778

• (2)血管新生と脱落膜化における性ステロイドホルモンによる調節機構の解明(シンポジウム2「子宮内膜の機能調節とその病態」,第62回日本産科婦人科学会・学術講演会)

• 岡田 英孝
• 日本産科婦人科學會雜誌 62(11), 2337-2349, 2010-11-01
• … Several mediators regulate angiogenesis, including, vascular endothelial growth factor (VEGF), soluble VEGF receptor 1 (sVEGFR-1) as a VEGF antagonist, and stromal cell-derived factor 1 (SDF-1/CXCL12). … Firstly, we determined whether E can regulate VEGF and sVEGFR-1 as a VEGF antagonist, and SDF-1 in human endometrial stromal cells (ESCs) and to determine whether SDF-1 can induce the proliferation mediated by its receptor (CXCR4) in the human endometrium. …
• NAID 110007880688

• Differential effects of interleukin-12 and interleukin-15 on expansion of NK cell receptor-expressing CD8+ T cells

• Sugita Junichi,Tanaka Junji,Yasumoto Atsushi,Shiratori Souichi,Wakasa Kentaro,Kikuchi Misato,Shigematsu Akio,Kondo Takeshi,Asaka Masahiro,Imamura Masahiro
• Annals of Hematology 89(2), 115-120, 2010-02
• … We investigated both inhibitory NK receptor (CD94/NKG2A) expression and stimulatory NKR (NKG2D) expression on T cells after stimulation with cytokines (IL-12 or IL-15). … Cytolytic NKR-expressing CD8+ T cells were expanded from normal adult peripheral blood mononuclear cells using anti-CD3 monoclonal antibody and cytokines (IL-12 or IL-15). …
• NAID 120002725525

Related Links

• IL15RA interleukin 15 receptor, alpha [Homo sapiens (human)]

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping ...

• Interleukin-15 biology and its therapeutic implications in cancer

Interleukin-15 receptor The heterotrimeric IL-15 receptor is composed of a beta subunit (IL-2R/15Rβ) that is shared with the IL-2 receptor, a common gamma subunit (γc) shared with IL-2, IL-4, IL-7, IL-9 and IL-21, and a unique alpha ...

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★リンクテーブル★

リンク元	「IL-15 receptor」「インターロイキン15受容体」
拡張検索	「interleukin-15 receptor alpha subunit」
関連記事	「interleukin」「interleukins」

「IL-15 receptor」

　　[★]

• インターロイキン15受容体、IL-15受容体、IL-15レセプター

関

interleukin-15 receptor

「インターロイキン15受容体」

　　[★]

英

interleukin-15 receptor、IL-15 receptor

関

IL-15受容体、IL-15レセプター

「interleukin-15 receptor alpha subunit」

　　[★]

• インターロイキン15受容体αサブユニット

「interleukin」

　　[★] インターロイキン IL 　

「interleukins」

　　[★] インターロイキン IL