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insulin-like growth factor binding protein 3
insulin-like growth factor binding protein-3

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  • Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels.
  • Bonilla C1,2, Lewis SJ1,2, Rowlands MA1, Gaunt TR1,2, Davey Smith G1,2, Gunnell D1, Palmer T3, Donovan JL1, Hamdy FC4, Neal DE4,5, Eeles R6,7, Easton D8, Kote-Jarai Z6, Al Olama AA8, Benlloch S8, Muir K9,10, Giles GG11,12, Wiklund F13, Grönberg H13, Haiman CA14, Schleutker J15,16, Nordestgaard BG17, Travis RC18, Pashayan N19,20, Khaw KT21, Stanford JL22,23, Blot WJ24, Thibodeau S25, Maier C26,27, Kibel AS28,29, Cybulski C30, Cannon-Albright L31, Brenner H32,33,34, Park J35, Kaneva R36, Batra J37, Teixeira MR38,39, Pandha H40; PRACTICAL consortium, Lathrop M41,42, Martin RM1,2,43, Holly JM43,44.
  • International journal of cancer.Int J Cancer.2016 Oct 1;139(7):1520-33. doi: 10.1002/ijc.30206. Epub 2016 Jun 23.
  • Circulating insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are associated with prostate cancer. Using genetic variants as instruments for IGF peptides, we investigated whether these associations are likely to be causal. We identified from the literature 56 single nucleotide p
  • PMID 27225428
  • Time dependent impact of perinatal hypoxia on growth hormone, insulin-like growth factor 1 and insulin-like growth factor binding protein-3.
  • Kartal Ö1,2, Aydınöz S2, Kartal AT1,3, Kelestemur T1, Caglayan AB1, Beker MC1, Karademir F2, Süleymanoğlu S2, Kul M2, Yulug B1, Kilic E4.
  • Metabolic brain disease.Metab Brain Dis.2016 Aug;31(4):827-35. doi: 10.1007/s11011-016-9816-z. Epub 2016 Mar 4.
  • Hypoxic-ischemia (HI) is a widely used animal model to mimic the preterm or perinatal sublethal hypoxia, including hypoxic-ischemic encephalopathy. It causes diffuse neurodegeneration in the brain and results in mental retardation, hyperactivity, cerebral palsy, epilepsy and neuroendocrine disturban
  • PMID 26943480
  • Investigation of serum levels and tissue expression of two genes IGFBP-2 and IGFBP-3 act as potential biomarker for predicting the progression and survival in patients with glioblastoma multiforme.
  • Abdolhoseinpour H1, Mehrabi F2, Shahraki K3, Khoshnood RJ4, Masoumi B5, Yahaghi E6, Goudarzi PK7.
  • Journal of the neurological sciences.J Neurol Sci.2016 Jul 15;366:202-6. doi: 10.1016/j.jns.2016.05.018. Epub 2016 May 14.
  • BACKGROUND: Identification of genetic copy number changes in glial tumors is of importance in the context of improved/refined diagnostic, prognostic procedures and therapeutic decision-making. Blood-derived biomarkers, therefore, would be useful as minimally invasive markers that could support diagn
  • PMID 27288807


  • Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice
  • Sasaki Tsutomu,Kuroko Mitsutaka,Sekine Sawako,Matsui Sho,Kikuchi Osamu,Susanti Vina Yanti,Kobayashi Masaki,Tanaka Yoshinori,Yuasa Tomoyuki,Kitamura Tadahiro
  • Endocrine Journal advpub(0), 2015
  • … db/db mice presented with stunted growth, accompanied by decreased plasma levels of free IGF1 and IGFBP-3, indicating the down-regulation of GH/IGF1 axis. …
  • NAID 130005077725
  • Thyroid and growth hormone concentrations in 8-year-old children exposed in utero to dioxins and polychlorinated biphenyls
  • Su Pen-Hua,Chen Hsiao-Yen,Chen Suh-Jen [他],Chen Jia-Yuh,Liou Saou-Hsing,Wang Shu-Li
  • The Journal of Toxicological Sciences 40(3), 309-319, 2015
  • … Girls exposed to high PCB levels had significantly lower IGF-binding protein-3 (IGFBP-3) concentrations than girls exposed to low levels (P = 0.038). … Low levels of in utero exposure to PCDD/F+PCB and high indicator PCB levels were significantly associated with reduced serum concentrations of IGFBP-3. …
  • NAID 130005068418
  • アデノイド・扁桃摘出術後, 血清IGF-1, IGFBP-3値を含めた成長経過を観察した, SAS合併低身長児例
  • 榎本 美紀,遠藤 志織,橋本 泰幸,三澤 清,鈴木 高広,影山 桃子,峯田 周幸
  • 耳鼻咽喉科臨床. 補冊 = Practica otologica. Suppl. (136), 150-154, 2013-08-01
  • NAID 10031188281


インスリン様成長因子結合蛋白3型, IGFBP‐3(insulin-like growth factor binding protein-3) 試薬販売中止のため(平成24年3月30日まで) 測定法: RIA-2 抗体法 IRMA法(固相法)平成17年3月25日まで 外注会社 ...
血中IGFBP-3は内因性のGH分泌動態を反映し,またGHより半減期が長く安定なことからGHの間接的な指標として有用である.特にGH分泌不全症(成長ホルモン分泌不全性低身長症)の診断にその臨床的意義がある. IGF-1は肝細胞で ...



リンク元insulin-like growth factor binding protein 3」「インスリン様成長因子結合タンパク質3」「インスリン様増殖因子結合タンパク質3

insulin-like growth factor binding protein 3」





insulin-like growth factor binding protein 3IGFBP-3



insulin-like growth factor binding protein 3IGFBP-3



IGF-binding proteininsulin-like growth factor binding protein
IGF binding protein



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