WordNet

the set of all points or lines that satisfy or are determined by specific conditions; "the locus of points equidistant from a given point is a circle"
the specific site of a particular gene on its chromosome
the 4th letter of the Roman alphabet (同)d

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1. ユーイング肉腫ファミリーの腫瘍の疫学、病理、および分子遺伝学 epidemiology pathology and molecular genetics of the ewing sarcoma family of tumors
2. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations
3. サラセミア症候群の分子病理 molecular pathology of the thalassemic syndromes
4. 急性骨髄性白血病の分子遺伝学 molecular genetics of acute myeloid leukemia
5. 黒色腫（メラノーマ）に対する遺伝的感受性 inherited susceptibility to melanoma

Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations.

Dashti HS1, Shea MK1, Smith CE1, Tanaka T1, Hruby A1, Richardson K1, Wang TJ1, Nalls MA1, Guo X1, Liu Y1, Yao J1, Li D1, Johnson WC1, Benjamin EJ1, Kritchevsky SB1, Siscovick DS1, Ordovás JM1, Booth SL1.
The American journal of clinical nutrition.Am J Clin Nutr.2014 Dec;100(6):1462-9. doi: 10.3945/ajcn.114.093146. Epub 2014 Oct 8.
BACKGROUND: Poor vitamin K status is linked to greater risk of several chronic diseases. Age, sex, and diet are determinants of circulating vitamin K; however, there is still large unexplained interindividual variability in vitamin K status. Although a strong genetic component has been hypothesized,
PMID 25411281

Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration.

Tschurtschenthaler M1, Wang J2, Fricke C3, Fritz TM3, Niederreiter L4, Adolph TE4, Sarcevic E5, Künzel S6, Offner FA5, Kalinke U7, Baines JF2, Tilg H8, Kaser A9.
Gut.Gut.2014 Dec;63(12):1921-31. doi: 10.1136/gutjnl-2013-305863. Epub 2014 Feb 20.
OBJECTIVE: Intestinal epithelial cells (IECs) at the internal/external interface orchestrate the mucosal immune response. Paneth cells secrete antimicrobial peptides and inflammatory mediators, protect from pathogens and shape the commensal microbiota. Prompted by the genetic association of the locu
PMID 24555997

Cyclin-dependent kinase 4 overexpression is mostly independent of gene amplification and constitutes an independent prognosticator for nasopharyngeal carcinoma.

Chen TJ1, Lee SW, Lin LC, Lin CY, Chang KY, Li CF.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.Tumour Biol.2014 Jul;35(7):7209-16. doi: 10.1007/s13277-014-1884-2. Epub 2014 Apr 27.
Data mining in the public domain demonstrates that cyclin-dependent kinase 4 (CDK4) is highly expressed in nasopharyngeal carcinomas (NPC). Associated with cyclin-D, CDK4 phosphorylates and inactivates retinoblastoma (Rb) protein family members and mediates progression through the G1- to the S-phase
PMID 24771220