WordNet
- the 4th letter of the Roman alphabet (同)d
PrepTutorEJDIC
- deuteriumの化学記号
- (おもに人称代名詞・固有名詞(人名),thereの後で)had, wouldの短縮形 / (疑問文でwhere,what,whenの後で)didの短縮形;Where'd he go?=Where did he go?
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/01/31 10:11:45」(JST)
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- 1. 色素沈着過剰を有する患者へのアプローチ approach to the patient with hyperpigmentation disorders
English Journal
- Fecal metabonomic study of a polysaccharide, MDG-1 from Ophiopogon japonicus on diabetic mice based on gas chromatography/time-of-flight mass spectrometry (GC TOF/MS).
- Zhu Y, Cong W, Shen L, Wei H, Wang Y, Wang L, Ruan K, Wu F, Feng Y.Author information Engineering Research Center of Modern Preparation Technology of TCM, Ministry of Education, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, PR China. wendycong@126.com fyi@vip.sina.com.AbstractType 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder with systemic complications and has been a worldwide epidemic. Ophiopogon japonicus is a traditional Chinese medicine used to treat diabetes for thousands of years. From our previous work, we know that MDG-1, a water-soluble β-d-fructan polysaccharide from O. japonicas could treat T2DM experimentally. However, MDG-1 is poorly absorbed and its mechanism of action is still unknown. Therefore, a GC TOF/MS-based metabonomic approach in combination with multivariate statistical analysis was performed to investigate the mechanism of MDG-1 in a spontaneous diabetic model. Female diabetic KKay mice (21 weeks old) were randomly divided into a diabetic group (n = 6, gavaged with distilled water) and a MDG-1-Diabetic group (n = 7, gavaged with MDG-1, 300 mg kg(-1)) and female C57BL/6 mice (21 weeks old) were set as controls (n = 6, gavaged with distilled water). After 8-weeks of treatment, feces samples were collected for GC-TOF/MS analysis. Consequently, 12 potential biomarkers were identified, including monosugars (d-tagatose, d-lyxose, d-erythrose, xylo-hexos-5-ulose, 2-deoxy-galactose), butanedioic acid, amino acids (phenylalanine, l-lysine, l-methionine, l-aspartic acid) and purine derivatives (7H-purine, 2'-deoxyinosine). We assume the monosugars and butanedioic acid were the fermentation products of MDG-1 by intestinal microbes and MDG-1 actions against diabetes might be accomplished through the absorbable monosugars and butanedioic acid via suppressing intestinal glucose absorption, enhancing liver glycogenesis, inhibiting glycogenolysis and promoting GLP-1 secretion. Besides, MDG-1 might alleviate diabetes and diabetic nephropathy by reducing 7H-purine and 2'-deoxyinosine. Further omics-driven studies including genomics, proteomics and metabonomics were considered to be carried out to provide direct evidence of gut microbiome contribution to MDG-1 actions.
- Molecular bioSystems.Mol Biosyst.2013 Dec 24;10(2):304-12. doi: 10.1039/c3mb70392d.
- Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder with systemic complications and has been a worldwide epidemic. Ophiopogon japonicus is a traditional Chinese medicine used to treat diabetes for thousands of years. From our previous work, we know that MDG-1, a water-soluble β-d-fructa
- PMID 24292023
- Erythrose revealed as furanose forms.
- Cabezas C, Peña I, Daly AM, Alonso JL.Author information Grupo de Espectroscopía Molecular (GEM), Edificio Quifima, Área de Química-Física, Laboratorios de Espectroscopia y Bioespectroscopia, Unidad Asociada CSIC, Parque Científico UVa, Universidad de Valladolid, 47005 Valladolid, Spain. jlalonso@qf.uva.es.AbstractA non-conventional vaporization method, using laser ablation of solid NaCl doped with d-erythrose, has been used to bring this sugar into the gas phase for rotational study. The jet cooled rotational spectrum of this C4 monosaccharide reveals the existence of two furanose forms, one α envelope and one β twist. Cooperative hydrogen bond networks and the anomeric effect have been found to be the main stabilization factors of the detected structures.
- Chemical communications (Cambridge, England).Chem Commun (Camb).2013 Nov 28;49(92):10826-8. doi: 10.1039/c3cc46405a.
- A non-conventional vaporization method, using laser ablation of solid NaCl doped with d-erythrose, has been used to bring this sugar into the gas phase for rotational study. The jet cooled rotational spectrum of this C4 monosaccharide reveals the existence of two furanose forms, one α envelope and
- PMID 24121543
Japanese Journal
- A New Route for Preparation of 2-Deoxy-D-ribofuranose Phospho Sugar
- Hanaya Tadashi,Tsukui Hiroyuki,Igi Naomi,Noguchi Ayashi,Kawamoto Heizan,Yamamoto Hiroshi
- Heterocycles 72(1), 411-420, 2007-04-13
- … The addition reaction of dimethyl phosphonate to (2R,4S)-4-(tertbutyldimethylsilyl)oxymethyl-2-methyl-1,3-dioxan-5-one (11a), followed by dehydroxylation, provided 1-O-(tert-butyldimethylsilyl)-3-deoxy-3-dimethoxyphosphinoyl-2,4-O-ethylidene-D-erythritol (13a). …
- NAID 120005323826
- rimary structure analysis and functional expression of erythrose reductases from erythrito卜producing fungi (Trichosporonoides megachiliensis SNG-42)
- Ookura Tetsuya,Azuma Keiko,Isshiki Kenji [他],TANIGUCHI Hajime,KASUMI Takafumi,KAWAMURA Yukio
- Bioscience, biotechnology, and biochemistry 69(5), 944-951, 2005-05-23
- … NADPH-dependent erythrose reductases (ERs) in erythritol-producing fungi, <I>Trichosporonoides megachiliensis</I> … SNG-42, catalyze the reduction of D-erythrose. … cDNAs encode erythrose reductases. …
- NAID 130000030325
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| 関連記事 | 「D」「erythrose」 |
「D」
- アスパラギン酸
- ジヒドロウリジン
- 遠位の distal,
- うつ病 depression
- 下行結腸 descending colon(大腸内視鏡検査の結果を記載するときに用いる)
「erythrose」
- 関
- threose