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Effect of transglutaminase-catalyzed glycosylation on the allergenicity and conformational structure of shrimp (Metapenaeus ensis) tropomyosin.

Yuan F1, Lv L1, Li Z2, Mi N1, Chen H3, Lin H1.
Food chemistry.Food Chem.2017 Mar 15;219:215-222. doi: 10.1016/j.foodchem.2016.09.139. Epub 2016 Sep 21.
Tropomyosin (TM), a myofibrillar protein, is a major allergen in shrimp. The aim of this study was to evaluate the effect of transglutaminase (TGase)-catalyzed glycosylation on the potential allergenicity and conformational structure of TM in Metapenaeus ensis. Results showed that glycosylation of T
PMID 27765219

Hierarchical self-assembly of heparin-PEG end-capped porous silica as a redox sensitive nanocarrier for doxorubicin delivery.

Nguyen Thi TT1, Tran TV1, Tran NQ1, Nguyen CK2, Nguyen DH3.
Materials science & engineering. C, Materials for biological applications.Mater Sci Eng C Mater Biol Appl.2017 Jan 1;70(Pt 2):947-954. doi: 10.1016/j.msec.2016.04.085. Epub 2016 Apr 25.
Porous nanosilica (PNS) has been attracting a great attention in fabrication carriers for drug delivery system (DDS). However, unmodified PNS-based carriers exhibited the initial burst release of loaded bioactive molecules, which may limit their potential clinical application. In this study, the sur
PMID 27772725

Gold nanoparticles coated with polysarcosine brushes to enhance their colloidal stability and circulation time in vivo.

Chen Y1, Xu Z1, Zhu D2, Tao X1, Gao Y1, Zhu H2, Mao Z3, Ling J4.
Journal of colloid and interface science.J Colloid Interface Sci.2016 Dec 1;483:201-10. doi: 10.1016/j.jcis.2016.08.038. Epub 2016 Aug 18.
Polysarcosine (PS), a non-ionic hydrophilic polypeptoid whose structure is similar to polypeptides, bearing repeating units of natural α-amino acid, has been used to stabilize gold nanoparticles (AuNPs) due to its excellent hydrophilicity and biocompatibility. Disulfide functionalized polysarcosine
PMID 27552428