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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/09/28 00:26:59」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/09/08 15:56:27」(JST)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/10/09 23:11:06」(JST)

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  • A mixture of amino acids and other small molecules present in the serum suppresses the growth of murine and human tumors in vivo.
  • Kulcsár G, Gaál D, Kulcsár PI, Schulcz A, Czömpöly T.SourceImmunal Ltd., Cancer Research and Product Development Laboratory, H-7630 Pécs, Finn u. 1/1., Hungary. kulcsar@immunal.hu.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2013 Mar 1;132(5):1213-21. doi: 10.1002/ijc.27756. Epub 2012 Aug 24.
  • Previously we have hypothesized that the small molecules which are selectively accumulated in cancer cells might participate in a non-immunological antitumor surveillance mechanism. We demonstrated earlier that a mixture of experimentally selected substances ("active mixture", AM: L-arginine, L-hist
  • PMID 22858865
  • Soluble FAS in the prediction of benefit from cetuximab and irinotecan for patients with advanced colorectal cancer.
  • Codony-Servat J, Garcia-Albeniz X, Pericay C, Alonso V, Escudero P, Fernández-Martos C, Gallego R, Martínez-Cardús A, Martinez-Balibrea E, Maurel J.SourceMedical Oncology Department, Hospital Clínic Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Catalonia, Spain, jordicodonyservat@yahoo.es.
  • Medical oncology (Northwood, London, England).Med Oncol.2013 Mar;30(1):428. doi: 10.1007/s12032-012-0428-0. Epub 2013 Jan 22.
  • The FAS/FASL system, comprising membrane-bound (mFAS and mFASL) and soluble forms (sFAS and sFASL), has been related to apoptosis driven by chemotherapy administration. In vitro experiments show chemotherapy upregulating membrane-bound forms, leading to an increase of receptor availability (at 24-72
  • PMID 23338968
  • Sequential docetaxel as adjuvant chemotherapy for node-positive or/and T3 or T4 breast cancer: clinical outcome (Mansoura University).
  • Sakr H, Hamed RH, Anter AH, Yossef T.SourceDepartment of Clinical Oncology and Nuclear Medicine, Mansoura University, Mansoura, Egypt.
  • Medical oncology (Northwood, London, England).Med Oncol.2013 Mar;30(1):457. doi: 10.1007/s12032-013-0457-3. Epub 2013 Jan 16.
  • This trial compared 6 cycles of fluorouracil, epirubicin, and cyclophosphamide (FEC) with a sequential regimen of 3 cycles of FEC followed by 3 cycles of docetaxel (FEC-D) as adjuvant treatment for women with node-positive or/and T3 or T4 breast cancer. Between January 2006 and January 2010, 657
  • PMID 23322524


  • 術前DCF療法が著効した食道原発内分泌細胞癌の1切除例
  • 前田 直見,白川 靖博,國府島 健,大原 利章,田邊 俊輔,野間 和広,櫻間 教文,藤原 俊義
  • 岡山医学会雑誌 126(1), 39-43, 2014-04-01
  • … We report a case of esophageal endocrine cell carcinoma showing histological complete response to neoadjuvant chemotherapy with docetaxel/cisplatin/5-fluorouracil (DCF). …
  • NAID 120005425654
  • TPF (Paclitaxel, Cisplatin, 5-fluorouracil)療法を施行した進行性陰茎癌の1例
  • 高本 大路,春日 純,湯村 寧 [他]
  • 泌尿器科紀要 = Acta urologica Japonica 60(2), 95-98, 2014-02
  • NAID 40020002867
  • Different Effects of Epigenetic Modifiers on the Cytotoxicity Induced by 5-Fluorouracil, Irinotecan or Oxaliplatin in Colon Cancer Cells
  • Ikehata Mika,Ogawa Mao,Yamada Yasuki [他]
  • Biological & pharmaceutical bulletin 37(1), 67-73, 2014-01
  • NAID 40019938783


5-Fluorouracil This medicine is an antimetabolite used to treat actinic (solar) keratoses, which is a skin growth caused by exposure to sunlight. Buy 5 ... Getting 5-Fluorouracil (5-Fu) 5-Fluorouracil ( Fluorouracil ®, Efudex®, Fluoroplex ®) was synthesized by Robert Duschinsky at the end of the 1950s.
[5-Fluorouracil] [51-21-8] | 価格や在庫、物性値などの詳細情報ページです。 ... ・川口の在庫は即日,つくばの在庫は2〜3日以内の出荷となります。 ・詳細につきましては,お手数ですが営業部までお問い合わせください。
5-Fluorouracil also known as Adrucil and 5-FU. Treats colon, rectal, breast, gastrointestinal, Ovarian, and head and neck cancer. ... Generic name: Fluorouracil Trade name: Adrucil ® Other names: 5-FU Chemocare.com uses ...


inhibits cell division by interfering with 5FU metabolismFluorouracil: mechanisms of action and FluorouracilFluorouracil: mechanisms of action and FLUOROURACIL 'EBEWE' 1000MG




fluorouracil FU
5-フルオロウラシル, 5-fluorouracil, 5-fluorouracilum, 5-FU
カルゾナール、フラキュール、ベントンルナコールルナポンテガフールカルモフール5-FU(5-FU錠、5-FU注、5-FU軟膏), Adrucil, Efudex, Fluoroplex
  • first aid step1 2006 p.307,308
  • ピリミジン代謝阻害


  • S期特異的


  • 5-FUは5F-dUMPに転換され、これが葉酸と共有結合して複合体を形成する。この複合体はthymidylate synthataseを阻害し、結果としてdTMPの合成を阻害させる。(dTMPの合成を阻害するという意味でMTXと同じ)


  • (USMLE)大腸癌や固形腫瘍、basal cel carcinoma






  [★] フルオロウラシル

WordNet   license wordnet

「an antimetabolite used to treat certain cancers」