英: dialyzer clearance

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1. 血液透析装置の概要overview of the hemodialysis apparatus [show details]
…used in every center. Clearance of various solutes from blood is a function of dialyzer efficiency. Dialyzer clearances are routinely reported as urea or creatinine clearances (small solutes) as well …
2. 血液-血液透析膜の相互作用に関与する生化学的機序biochemical mechanisms involved in blood hemodialysis membrane interactions [show details]
… biocompatibility. These include dialysate composition and temperature, the permeability of the dialysis membrane, the type of clearance (diffuse or convective), the initial sterilant (eg, ethylene oxide), reuse procedure …
3. 透析装置の再利用reuse of dialyzers [show details]
…report, the measured Kt/V (ie, dialyzer clearance for urea) was significantly lower in dialyzers that had been reused many times (mean 14^th reuse) compared with dialyzers that had only been reused a …
4. 家庭での短時間連日血液透析：低透析液容量によるアプローチshort daily home hemodialysis the low dialysate volume approach [show details]
…which is generally not as saturated with uremic solutes upon leaving the dialyzer. In conventional hemodialysis, urea clearance increases as either blood flow or dialysate flow rate increases. However …
5. 緊急血液透析acute hemodialysis prescription [show details]
… need to be increased in order to achieve adequate clearances. If a high-efficiency cellulose dialyzer is used, the urea clearance is similar to high-flux membranes, provided that blood flow is adequate …

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「dialyzer clearance」

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「クリアランス」

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英: clearance
同: 清掃値、浄化値

定義

1. ある物質について、単位時間あたりどれだけの量の血液をきれいにできるか。
2. ある物質が排泄されるために必要な単位時間あたりの血漿量
3. ある物質が単位時間に腎によって完全に除去(清掃)される血漿の量 (生理学実習1 実習テキスト p.4,SP.777-778)
4. it is defined as the rate of elimination of the drug from the body relative to the concentration of the drug in plasma

(PPC.42) [(amount/time)/(amount/volume)]

5. clearance is the rate at which plasma would have to be cleared of the drug to account for the observed kinetics of change of the total amount of drug in the body, assuming that all the drug in the body is present at the same concentration as that in the plasma.(PPC.42)