英: depolarization block

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1. 危篤状態の患者への神経筋遮断薬：使用、薬の選択、投与、副作用neuromuscular blocking agents in critically ill patients use agent selection administration and adverse effects [show details]
… function. In contrast, aminosteroid NMBA pharmacokinetics can be affected by liver dysfunction. Thus, because the half-life is prolonged in patients with hepatic insufficiency, pancuronium (increased volume …
2. 麻酔導入時の神経筋遮断薬の使用clinical use of neuromuscular blocking agents in anesthesia [show details]
…has no effect on the duration of depolarizing block . Acidosis – Acidosis, whether metabolic or respiratory in origin, can prolong the effects of NMBAs, by increasing NMBA affinity for postjunctional nAChRs …
3. 手術室外で成人に迅速導入気管挿管を行う際に用いる神経筋遮断薬（NMBA）neuromuscular blocking agents nmbas for rapid sequence intubation in adults outside of the operating room [show details]
… sedative and a NMBA in the emergency department (ED) . NMBAs are integral to the performance of RSI. Multiple randomized trials and observational studies demonstrate that the use of NMBAs improves success …
4. 麻酔下での神経筋遮断薬の作用のモニタリングmonitoring neuromuscular blockade [show details]
…that occur after TOF stimulation) are used as measures of the degree of nondepolarizing neuromuscular block. With depolarizing block, fade does not occur during TOF stimulation, unless phase II block develops …
5. 全身麻酔の維持：概要maintenance of general anesthesia overview [show details]
… cause hypotension . A neuromuscular blocking agent (NMBA) may be employed to improve surgical conditions in selected cases. Two classes of NMBAs exist: depolarizing (succinylcholine [SCh]) and nondepolarizing …