…immune deficiency and isolated ACTH deficiency . Proprotein convertase 1 deficiency – Case reports describe mutations in PCSK1, which encodes proprotein convertase subtilisin/kexin type 1, and are associated…
…deficiency has been described. Congenital deficiency of the proprotein convertase subtilisin/kexin type 1 gene (PCSK1), which encodes proprotein convertase 1/3, causes a severe multihormonal disorder marked…
…enteroendocrine cell development or function (eg, enteric anendocrinosis [NEUROG3 deficiency], proprotein convertase type 1 [PCSK1] deficiency, or Mitchell-Riley syndrome [RFX6]). Abnormal villus and…
… Proprotein convertase subtilisin/kexin type 9 inhibitors have been approved by regulatory agencies for the treatment of individuals with inadequately treated levels of low density lipoprotein-cholesterol …
…decreased clearance of lipoproteins . In a series of patients with glomerular proteinuria, levels of proprotein convertase subtilisin-kexin type 9 (PCSK9) correlated with a degree of proteinuria and levels of…