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1. ビリルビン代謝bilirubin metabolism [show details]
… urobilinogen excretion can be reduced, normal, or elevated in patients with hepatitis as noted above. Tubular reabsorption and instability of the pigment in acid urine can… Bilirubin is the catabolic product of heme metabolism. Within physiologic range, bilirubin has cytoprotective and beneficial metabolic effects, but in high levels it is potentially toxic. Fortunately …
2. チロシン代謝障害disorders of tyrosine metabolism [show details]
… bluish pigment become apparent in the ear cartilage and sclerae Tyrosine levels are normal. No approved therapy is available. Dietary restriction of tyrosine and phenylalanine reduce the excretion of homogentisic… (HT1; MIM# 276700), also known as hepatorenal tyrosinemia, is the most severe disorder of tyrosine metabolism. HT1 occurs in 1 in 12,000 to 1 in 100,000 individuals of Northern European descent . HT1 is caused …
3. ヘム色素誘発性急性腎障害の臨床的特徴および診断clinical features and diagnosis of heme pigment induced acute kidney injury [show details]
… unless pigment excretion is limited because of a low glomerular filtration… from the plasma by hepatic metabolism to bilirubin and, to a lesser extent, by glomerular filtration and renal metabolism .…
4. 先天性代謝異常：分類inborn errors of metabolism classification [show details]
… carbohydrate metabolism can lead to hypoglycemia, liver dysfunction, myopathy, and/or cardiomyopathy. These disorders include deficiencies of enzymes in the pathways of the metabolism of glycogen ,… plasma and amino acidurias when there is abnormal excretion of amino acids in the urine.…
5. 薬と肝臓：代謝および肝障害の機序drugs and the liver metabolism and mechanisms of injury [show details]
… developed as well . The liver is responsible for the selective uptake, concentration, metabolism, and excretion of the majority of drugs and toxins that are introduced into the body. While some parent …