"Onychia" redirects here. For the squid genus, see Onykia. For the genus of moth, see Onychia (moth).
This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. Find sources: "Nail disease" – news · newspapers · books · scholar · JSTOR(March 2008) (Learn how and when to remove this template message)
Medical condition
Nail disease or disorder
Onychia without granuloma
Specialty
Dermatology
A nail disease or onychosis is a disease or deformity of the nail. Although the nail is a structure produced by the skin and is a skin appendage, nail diseases have a distinct classification as they have their own signs and symptoms which may relate to other medical conditions. Some nail conditions that show signs of infection or inflammation may require medical assistance.
Contents
1Diseases
2Nail changes and conditions associated with them
2.1Pliability
2.2Shape and texture
2.3Discoloration of entire nail bed
2.4Other color changes and markings
3Treatment
4See also
5References
6External links
Diseases
Anatomy of the basic parts of a human nail. A. Nail plate; B. lunula; C. root; D. sinus; E. matrix; F. nail bed; G. eponychium; H. free margin.
Onychia is an inflammation of the nail folds (surrounding tissue of the nail plate) of the nail with formation of pus and shedding of the nail. Onychia results from the introduction of microscopic pathogens through small wounds.
Onychocryptosis, commonly known as "ingrown nails" (unguis incarnatus), can affect either the fingers or the toes. In this condition, the nail cuts into one or both sides of the nail bed, resulting in inflammation and possibly infection. The relative rarity of this condition in the fingers suggests that pressure from the ground or shoe against the toe is a prime factor. The movements involved in walking or other physical disturbances can contribute to the problem. Mild onychocryptosis, particularly in the absence of infection, can be treated by trimming and rounding the nail. More advanced cases, which usually include infection, are treated by surgically excising the ingrowing portion of the nail down to its bony origin and thermally or chemically cauterizing the matrix, or 'root', to prevent recurrence. This surgery is called matrixectomy. The best results are achieved by cauterizing the matrix with phenol. The Vandenbos Procedure is a highly effective method that focuses on excision of excessive nail fold tissue without affecting the healthy nail and nail matrix. The Vandenbos Procedure is showing high success rates in eliminating onychocryptosis without altering the normal nail. Another, much less effective, treatment is excision of the matrix, sometimes called a 'cold steel procedure'.
Ingrown nail in hallux toe
Onychodystrophy is a deformation of the nails that can result from cancer chemotherapy which includes bleomycin, hydroxyurea, or 5-fluorouracil. It can include discoloration of the nail, or dyschromia.
Onychogryposis, also called "ram's-horn nail", is a thickening and increase in curvature of the nail. It is usually the result of injury to the matrix. It may be partially hereditary and can also occur as a result of long-term neglect. It is most commonly seen in the great toe but may be seen in other toes as well as the fingernails. An affected nail has many grooves and ridges, is brownish in color, and grows more quickly on one side than on the other. The thick curved nail is difficult to cut, and often remains untrimmed, exacerbating the problem.
Onychomycosis in every nail of the right foot.
Onycholysis is a loosening of the exposed portion of the nail from the nail bed, usually beginning at the free edge and continuing to the lunula. It is frequently associated with an internal disorder, trauma, infection, nail fungi, allergy to nail enhancement products, or side effects of drugs.
Onychomadesis is the separation and falling off of a nail from the nail bed. Common causes include localized infection, minor injury to the matrix bed, or severe systemic illness. It is sometimes a side effect of chemotherapy or x-ray treatments for cancer. A new nail plate will form once the cause of the disease is removed.
Onychomycosis, also known as tinea unguium, is a contagious infection of the nail caused by the same fungal organisms which cause ringworm of the skin (Trichophyton rubrum or T. mentagrophytes, rarely other trichophyton species or Epidermophyton floccosum[1]). It can result in discoloration, thickening, chalkiness, or crumbling of the nails and is often treated by powerful oral medications which, rarely, can cause severe side effects including liver failure. Mild onychomycosis sometimes responds to a combination of topical antifungal medication, sometimes applied as special medicinal nail lacquer, and periodic filing of the nail surface. For advanced onychomycosis, especially if more than one nail is infected, systemic medication (pills) is preferred. Home remedies are often used, although their effectiveness is disputed.
Subungual hematoma (mild)
Onychophosis is a growth of horny epithelium in the nail.
Onychoptosis is the periodic shedding of one or more nails, in whole or part. This condition may follow certain diseases such as syphilis, or can result from fever, trauma, systemic upsets or adverse reaction to drugs.
Onychorrhexis also known as brittle nails, is brittleness with breakage of fingernails or toenails.
Paronychia is a bacterial or fungal infection where the nail and skin meet.
Koilonychia is when the nail curves upwards (becomes spoon-shaped) due to an iron deficiency. The normal process of change is: brittle nails, straight nails, spoon-shaped nails.
Subungual hematoma occurs when trauma to the nail results in a collection of blood, or hematoma, under the nail. It may result from an acute injury or from repeated minor trauma such as running in undersized shoes. Acute subungual hematomas are quite painful, and are usually treated by releasing the blood by creating a small hole in the nail. Drilling and thermal cautery are common methods for creating the hole. Thermal cautery is not used on acrylic nails because they are flammable.
Onychomatricoma, a tumor of the nail matrix.
Nail pemphigus, an auto-immune disease.
Erythronychia, red bands in the nail from some inflammatory conditions.
Melanonychia, a black, brown or grey discoloration of the nail, with numerous causes.
Nail changes and conditions associated with them
Nail inspection can give hints to the internal condition of the body as well.
Nail disease can be very subtle and should be evaluated by a dermatologist with a focus in this particular area of medicine. A nail technician may be the first to note a subtle change in nail health.[2][3][4]
Pliability
Brittleness is associated with iron deficiency, thyroid problems,[5] and impaired kidney function.
Splitting and fraying are associated with psoriasis and deficiencies of folic acid, protein, and Vitamin C.
Unusual thickness is associated with circulation problems.
Shape and texture
Nail clubbing - nails that curve down around the fingertips with nailbeds that bulge is associated with oxygen deprivation and lung, heart, or liver disease.
Koilonychia - spooning, or nails that grow upwards. Associated with iron-deficiency anaemia or vitamin B12 deficiency.[citation needed]
Pitting of the nails is associated with psoriasis.
Beau's lines are horizontal ridges in the nail.
Habit-tic deformity is a condition similar to Beau's Lines caused by long-term skin picking.
Discoloration of entire nail bed
Yellowing of the nail bed is associated with chronic bronchitis, lymphatic problems, diabetes, and liver disorders.
Brown or copper nail beds are associated with arsenic or copper poisoning, and local fungal infection.
Redness is associated with heart conditions.
Other color changes and markings
Melanonychia (longitudinal streaking that darkens or does not grow out), especially on the thumb or big toe, may indicate subungual melanoma.
White lines across the nail (leukonychia striata, or transverse leukonychia) may be Mees' lines or Muehrcke's lines.
Small white patches are known as leukonychia punctata.
Dark nails are associated with B12 deficiency.
Stains of the nail plate (not the nail bed) are associated with smoking, and henna use.
Splinter hemorrhages (or haemorrhages) are tiny blood clots that tend to run vertically under the nails.
Drug-induced nail changes are caused by drug usage which may result in various abnormalities.[6]: 665–6
Treatment
In approximately half of suspected nail fungus cases there is actually no fungal infection, but only some nail dystrophy.[7] Before beginning oral antifungal therapy the health care provider should confirm a fungal infection.[7] Administration of treatment to persons without an infection is unnecessary health care and causes needless exposure to side effects.[7]
See also
Hangnail
List of cutaneous conditions
Occupational hazards associated with exposure to human nail dust
Yellow nail syndrome
References
^Hall, John C. (2006). "25. Dermatologic mycology.". In John C. Hall (ed.). Sauer's Manual of Skin Diseases (9th ed.). Philadelphia: Lippincott Williams & Wilkins. pp. 244–266. ISBN 0-7817-2947-5.
^Common nail tumors.
Baran R, Richert B., Dermatol Clin. 2006 Jul;24(3):297-311. Review.
^Dealing with melanonychia. Tosti A, Piraccini BM, de Farias DC. Semin Cutan Med Surg. 2009 Mar;28(1):49-54. Review.
^The nail in systemic diseases. Tosti A, Iorizzo M, Piraccini BM, Starace M. Dermatol Clin. 2006 Jul;24(3):341-7. Review.
^Baylor All Saints Medical Centers: Thyroid Disease
^Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
^ abcAmerican Academy of Dermatology (February 2013), "Five Things Physicians and Patients Should Question", Choosing Wisely: an initiative of the ABIM Foundation, American Academy of Dermatology, retrieved 5 December 2013, which cites
Roberts, D. T.; Taylor, W. D.; Boyle, J.; British Association of Dermatologists (2003). "Guidelines for treatment of onychomycosis". The British Journal of Dermatology. 148 (3): 402–410. doi:10.1046/j.1365-2133.2003.05242.x. PMID 12653730.
Mehregan, D. R.; Gee, S. L. (1999). "The cost effectiveness of testing for onychomycosis versus empiric treatment of onychodystrophies with oral antifungal agents". Cutis. 64 (6): 407–410. PMID 10626104.
External links
Classification
D
ICD-10: L60, Q84.3-Q84.6
ICD-9-CM: 703, 757.5
MeSH: D009260
DiseasesDB: 23092
External resources
MedlinePlus: 003247
eMedicine: orthoped/421
Wikimedia Commons has media related to Diseases and disorders of the nails.
Fungal Nail Infections - explanation covering causes, treatment, and prevention
Links to pictures of Nail Diseases (Hardin MD/Univ of Iowa)
Nail Abnormalities: Clues to Systemic Disease
Links to pictures of Toenail Diseases (Wiggins MD)
v
t
e
Disorders of skin appendages
Nail
thickness: Onychogryphosis
Onychauxis
color: Beau's lines
Yellow nail syndrome
Leukonychia
Azure lunula
shape: Koilonychia
Nail clubbing
behavior: Onychotillomania
Onychophagia
other: Ingrown nail
Anonychia
ungrouped: Paronychia
Acute
Chronic
Chevron nail
Congenital onychodysplasia of the index fingers
Green nails
Half and half nails
Hangnail
Hapalonychia
Hook nail
Ingrown nail
Lichen planus of the nails
Longitudinal erythronychia
Malalignment of the nail plate
Median nail dystrophy
Mees' lines
Melanonychia
Muehrcke's lines
Nail–patella syndrome
Onychoatrophy
Onycholysis
Onychomadesis
Onychomatricoma
Onychomycosis
Onychophosis
Onychoptosis defluvium
Onychorrhexis
Onychoschizia
Platonychia
Pincer nails
Plummer's nail
Psoriatic nails
Pterygium inversum unguis
Pterygium unguis
Purpura of the nail bed
Racquet nail
Red lunulae
Shell nail syndrome
Splinter hemorrhage
Spotted lunulae
Staining of the nail plate
Stippled nails
Subungual hematoma
Terry's nails
Twenty-nail dystrophy
Hair
Hair loss/ Baldness
noncicatricial alopecia: Alopecia
areata
totalis
universalis
Ophiasis
Androgenic alopecia (male-pattern baldness)
Hypotrichosis
Telogen effluvium
Traction alopecia
Lichen planopilaris
Trichorrhexis nodosa
Alopecia neoplastica
Anagen effluvium
Alopecia mucinosa
cicatricial alopecia: Pseudopelade of Brocq
Central centrifugal cicatricial alopecia
Pressure alopecia
Traumatic alopecia
Tumor alopecia
Hot comb alopecia
Perifolliculitis capitis abscedens et suffodiens
Graham-Little syndrome
Folliculitis decalvans
ungrouped: Triangular alopecia
Frontal fibrosing alopecia
Marie Unna hereditary hypotrichosis
Hypertrichosis
Hirsutism
Acquired
localised
generalised
patterned
Congenital
generalised
localised
X-linked
Prepubertal
Acneiform eruption
Acne
Acne vulgaris
Acne conglobata
Acne miliaris necrotica
Tropical acne
Infantile acne/Neonatal acne
Excoriated acne
Acne fulminans
Acne medicamentosa (e.g., steroid acne)
Halogen acne
Iododerma
Bromoderma
Chloracne
Oil acne
Tar acne
Acne cosmetica
Occupational acne
Acne aestivalis
Acne keloidalis nuchae
Acne mechanica
Acne with facial edema
Pomade acne
Acne necrotica
Blackhead
Lupus miliaris disseminatus faciei
Rosacea
Perioral dermatitis
Granulomatous perioral dermatitis
Phymatous rosacea
Rhinophyma
Blepharophyma
Gnathophyma
Metophyma
Otophyma
Papulopustular rosacea
Lupoid rosacea
Erythrotelangiectatic rosacea
Glandular rosacea
Gram-negative rosacea
Steroid rosacea
Ocular rosacea
Persistent edema of rosacea
Rosacea conglobata
variants
Periorificial dermatitis
Pyoderma faciale
Ungrouped
Granulomatous facial dermatitis
Idiopathic facial aseptic granuloma
Periorbital dermatitis
SAPHO syndrome
Follicular cysts
"Sebaceous cyst"
Epidermoid cyst
Trichilemmal cyst
Steatocystoma
simplex
multiplex
Milia
Inflammation
Folliculitis
Folliculitis nares perforans
Tufted folliculitis
Pseudofolliculitis barbae
Hidradenitis
Hidradenitis suppurativa
Recurrent palmoplantar hidradenitis
Neutrophilic eccrine hidradenitis
Ungrouped
Acrokeratosis paraneoplastica of Bazex
Acroosteolysis
Bubble hair deformity
Disseminate and recurrent infundibulofolliculitis
Erosive pustular dermatitis of the scalp
Erythromelanosis follicularis faciei et colli
Hair casts
Hair follicle nevus
Intermittent hair–follicle dystrophy
Keratosis pilaris atropicans
Kinking hair
Koenen's tumor
Lichen planopilaris
Lichen spinulosus
Loose anagen syndrome
Menkes kinky hair syndrome
Monilethrix
Parakeratosis pustulosa
Pili (Pili annulati
Pili bifurcati
Pili multigemini
Pili pseudoannulati
Pili torti)
Pityriasis amiantacea
Plica neuropathica
Poliosis
Rubinstein–Taybi syndrome
Setleis syndrome
Traumatic anserine folliculosis
Trichomegaly
Trichomycosis axillaris
Trichorrhexis (Trichorrhexis invaginata
Trichorrhexis nodosa)
Trichostasis spinulosa
Uncombable hair syndrome
Wooly hair nevus
Sweat glands
Eccrine
Miliaria
Colloid milium
Miliaria crystalline
Miliaria profunda
Miliaria pustulosa
Miliaria rubra
Occlusion miliaria
Postmiliarial hypohidrosis
Granulosis rubra nasi
Ross’ syndrome
Anhidrosis
Hyperhidrosis
Generalized
Gustatory
Palmoplantar
Apocrine
Body odor
Chromhidrosis
Fox–Fordyce disease
Sebaceous
Sebaceous hyperplasia
v
t
e
Congenital malformations and deformations of skin appendages
Nail disease
Anonychia
Leukonychia
Pachyonychia congenita/Onychauxis
Koilonychia
Hair disease
hypotrichosis/abnormalities: keratin disease
Monilethrix
IBIDS syndrome
Sabinas brittle hair syndrome
Pili annulati
Pili torti
Uncombable hair syndrome
Björnstad syndrome
Giant axonal neuropathy with curly hair
hypertrichosis: Zimmermann–Laband syndrome
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
Journal of cutaneous medicine and surgery.J Cutan Med Surg.2015 Nov;19(6):595-9. doi: 10.1177/1203475415588659. Epub 2015 May 29.
BACKGROUND: Nail-patella syndrome (NPS) is an autosomal dominant disorder with a variable interfamilial and intrafamilial clinical expressivity and penetrance. It is caused by loss-of-function heterozygous mutation in the LIM-homeodomain transcription factor (LMX1B) located on chromosome 9q. The ple
Determination of Radiographic Healing: An Assessment of Consistency Using RUST and Modified RUST in Metadiaphyseal Fractures.
Litrenta J1, Tornetta P 3rd, Mehta S, Jones C, OʼToole RV, Bhandari M, Kottmeier S, Ostrum R, Egol K, Ricci W, Schemitsch E, Horwitz D.
Journal of orthopaedic trauma.J Orthop Trauma.2015 Nov;29(11):516-20. doi: 10.1097/BOT.0000000000000390.
OBJECTIVE: To determine the reliability of the Radiographic Union Scale for Tibia (RUST) score and a new modified RUST score in quantifying healing and to define a value for radiographic union in a large series of metadiaphyseal fractures treated with plates or intramedullary nails.DESIGN: Healing w