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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/06/29 22:39:51」(JST)

Isepamicin (also Isepamycin) is an aminoglycoside antibiotic.

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English Journal

Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates.

Livermore DM, Mushtaq S, Warner M, Zhang JC, Maharjan S, Doumith M, Woodford N.SourceAntibiotic Resistance Monitoring & Reference Laboratory, HPA Microbiology Services, London, UK. david.livermore@hpa.org.uk
The Journal of antimicrobial chemotherapy.J Antimicrob Chemother.2011 Jan;66(1):48-53. Epub 2010 Nov 14.
BACKGROUND: the emergence of carbapenemases in Enterobacteriaceae is driving a search for therapeutic alternatives. We tested ACHN-490, a sisomicin derivative that evades all plasmid-mediated aminoglycoside-modifying enzymes, against 82 carbapenem-resistant Enterobacteriaceae isolates. Comparators i
PMID 21078604

Resonance Rayleigh-scattering spectral method for the determination of some aminoglycoside antibiotics using CdTe quantum dots as a probe.

Wang L, Peng J, Liu Z, He Y.SourceKey Laboratory on Luminescence and Real-time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, People's Republic of China.
Luminescence : the journal of biological and chemical luminescence.Luminescence.2010 Nov-Dec;25(6):424-30. doi: 10.1002/bio.1170. Epub 2009 Sep 10.
A novel method is used for the determination of some aminoglycoside antibiotics (AGs) such as etimicin (ETM), isepamicin (ISP) and amikacin (AMK). It is based on the resonance Rayleigh scattering (RRS) intensities enhanced by AGs-induced CdTe quantum dots aggregation. Under the optimum conditions, t
PMID 19743528

Prophylactic use of isepamicin and levofloxacin for transrectal prostate biopsy : A retrospective single center study

SHIGEMURA Katsumi,YASUFUKU Tomihiko,YAMASHITA Masuo,ARAKAWA Soichi,FUJISAWA Masato
International journal of urology 16(9), 723-725, 2009-09-01
NAID 10025617767

Determination of Isepamicin in Human Plasma by HPLC with Fluorescence Detection after Derivatization Using 6-Aminoquinolyl-N-hydroxysuccinimidyl-carbamate(Analytical Biochemistry)

HOSOKAWA Shin,NAKAMURA Katsunori,FUJITA Yukiyoshi,HORIUCHI Ryuya,YAMAMOTO Koujirou
Biological & pharmaceutical bulletin 31(10), 1866-1869, 2008-10-01
… A simple and rapid high-performance liquid chromatographic method has been developed for determination in human plasma of isepamicin (ISP), an aminoglycoside antibiotic agent. …
NAID 110006936324

リンク元	「イセパマイシン」
拡張検索	「isepamicin sulfate」

Isepamicin
Systematic (IUPAC) name
	(2S)-3-amino-N-((1R,2S,3S,4R,5S)-5-amino-4-[(6-amino-6-deoxy-D-glucopyranosyl)oxy]-2-{[3-deoxy-4-C-methyl-3-(methylamino)-L-arabinopyranosyl]oxy}-3-hydroxycyclohexyl)-2-hydroxypropanamide
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
ATC code	J01GB11
PubChem	CID 456297
UNII	G7K224460P
ChEMBL	CHEMBL272080
Synonyms	(2S)-3-Amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-[(3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-2-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylaminooxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxypropanamide
Chemical data
Formula	C22H43N5O12
Mol. mass	569.60 g/mol
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