急性拒絶反応
| hyperacute rejection | Antibody mediated due to the presence of preformed antidonor antibodies in the transplant recipient.
Occurs within minutes after transplantation. |
| acute rejection | Cell mediated due to cytotoxic T lymphocytes reacting against foreign MHCs.
Occurs weeks after transplantation. Reversible with immunosuppressants such as cyclosporin and OKT3. |
| chronic rejection | Antibody-mediated vascular damage (fibrinoid necrosis);
Occurs months to years after transplantation. Irreversible. |