リンパ球抗原受容体
BCRとTCRの成立過程における差異
| BCR | TCR | ||
| v-region assembly | somatic reombination of DNA | 有り | 有り |
| junctional diversity | imprecise joining, N-sequence insertion in DNA | 有り | 有り |
| transcriptional activation | activation of promoter by proximity to the enhancer | 有り | 有り |
| switch recombination | somatic recombination of DNA | 有り | 無し |
| somatic hypermutation | DNA point mutation | 有り | 無し |
| IgM, IgD expression on surface | differential splicing of DNA | 有り | 無し |
| membrane vs secreted form | differential splicing of RNA | 有り | 無し |