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1. 成人における視覚障害：屈折障害と老視 visual impairment in adults refractive disorders and presbyopia
2. 小児における水晶体偏位（水晶体脱臼） ectopia lentis dislocated lens in children
3. 小児における白内障 cataract in children

English Journal

Guan JJ1, Kramer GD1, MacLean K1, Farukhi A1, Li H1, Reiter N1, Werner L1, Mamalis N1.
Clinical & experimental ophthalmology.Clin Experiment Ophthalmol.2016 Jun 13. doi: 10.1111/ceo.12786. [Epub ahead of print]
PURPOSE: To evaluate the stability and ease of replacement of a new modular intraocular lens (IOL) system consisting of a hydrophobic acrylic base unit and a hydrophobic acrylic optic in the rabbit model.METHODS: Five New Zealand white rabbits were utilized. Bilateral phacoemulsification was perform
PMID 27298269

Trikha S1,2, Agrawal S1, Saffari SE2,3, Jayaswal R1, Yang YF1.
Eye (London, England).Eye (Lond).2016 Jun 10. doi: 10.1038/eye.2016.108. [Epub ahead of print]
PurposeTo evaluate the visual outcomes of patients with zonular dialysis following cataract surgery.Patients and methodsMedical records of all patients with documented zonular dialysis, either pre- or peri-operatively, undergoing cataract surgery between 2004-2010 at Queen Alexandra Hospital, Portsm
PMID 27285326

Human βA3/A1-crystallin splicing mutation causes cataracts by activating the unfolded protein response and inducing apoptosis in differentiating lens fiber cells.

Ma Z1, Yao W2, Chan CC3, Kannabiran C1, Wawrousek E4, Hejtmancik JF5.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Jun;1862(6):1214-27. doi: 10.1016/j.bbadis.2016.02.003. Epub 2016 Feb 4.
βγ-Crystallins, having a uniquely stable two domain four Greek key structure, are crucial for transparency of the eye lens,. Mutations in lens crystallins have been proposed to cause cataract formation by a variety of mechanisms most of which involve destabilization of the protein fold. The underl
PMID 26851658

山本香織/篠崎和美/堀貞夫
東京女子医科大学雑誌 82(E1), E101-E108, 2012-01-31
目的:白内障において、水晶体上皮細胞がアポトーシスに陥っている数および分布を観察し、さらにこれらと、白内障に影響する因子との関連があるか検討したので報告する。,対象および方法:対象は、白内障手術時に水晶体前嚢片の採取が可能であった29眼である。全身疾患および背景因子は、糖尿病があるものは13例15眼、糖尿病がないものは11例14眼で、この中にはアトピー性皮膚炎1例1眼、ステロイド全身投与歴2例3眼 …
NAID 110008767960