ベロ毒素
- 関
- verotoxin
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/11 05:00:01」(JST)
[Wiki en表示]
Verocytotoxin is a Shiga-like toxin produced by the E. coli strain O157, and Shigella type 1.
It causes acute renal failure in children, as a result of Haemolytic uraemic syndrome.
The toxin has two parts. The A part damages gut epithelium through inhibiting its protein synthesis, facilitating entry to the blood stream. The 5 B parts are adapted to inserting the A part into epithelial cells.
References
- Kumar and Clarke, Clinical Medicine, 6th Ed., p636
Further reading
- Reena Khanna; Laurie Waechter; Jan Sargeant; William F. Clark; Amit X. Garg (March 20, 2008). "Environmental prevention of human disease from verocytotoxin-producing Escherichia coli". Nephrology Dialysis Transplantation (Oxford University Press) 23 (6): 1819-1822. doi:10.1093/ndt/gfn125. ISSN 0931-0509. PMID 18356186.
- Michelacci, Valeria; Grande, Laura; Tozzoli, Rosangela; Maugliani, Antonella; Caprioli, Alfredo; Morabito, Stefano (July 2014). "Identification of two allelic variants of toxB gene and investigation of their distribution among Verocytotoxin-producing Escherichia coli". International Journal of Medical Microbiology 304 (5-6): 730-734. doi:10.1016/j.ijmm.2014.05.009.
UpToDate Contents
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- 1. 消化管疾患関連関節炎 arthritis associated with gastrointestinal disease
English Journal
- Diversity of Shiga toxin-producing Escherichia coli in sheep flocks of Paraná State, southern Brazil.
- Martins FH1, Guth BE2, Piazza RM3, Leão SC4, Ludovico A5, Ludovico MS1, Dahbi G6, Marzoa J6, Mora A6, Blanco J6, Pelayo JS1.
- Veterinary microbiology.Vet Microbiol.2015 Jan 30;175(1):150-6. doi: 10.1016/j.vetmic.2014.11.003. Epub 2014 Nov 13.
- Sheep constitute an important source of zoonotic pathogens as Shiga toxin-producing Escherichia coli (STEC). In this study, the prevalence, serotypes and virulence profiles of STEC were investigated among 130 healthy sheep from small and medium farms in southern Brazil. STEC was isolated from 65 (50
- PMID 25465174
- Inter-laboratory comparison of multi-locus variable-number tandem repeat analysis (MLVA) for verocytotoxin-producing Escherichia coli O157 to facilitate data sharing.
- Holmes A1, Perry N2, Willshaw G2, Hanson M1, Allison L1.
- Epidemiology and infection.Epidemiol Infect.2015 Jan;143(1):104-7. doi: 10.1017/S0950268814000739. Epub 2014 Apr 4.
- SUMMARY Multi-locus variable number tandem repeat analysis (MLVA) is used in clinical and reference laboratories for subtyping verocytotoxin-producing Escherichia coli O157 (VTEC O157). However, as yet there is no common allelic or profile nomenclature to enable laboratories to easily compare data.
- PMID 24703302
- A novel transducible chimeric phage from Escherichia coli O157:H7 Sakai strain encoding Stx1 production.
- Sváb D1, Bálint B2, Maróti G3, Tóth I4.
- Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.Infect Genet Evol.2015 Jan;29:42-7. doi: 10.1016/j.meegid.2014.10.019. Epub 2014 Nov 4.
- Shiga toxin-producing Escherichia coli (STEC), and especially enterohaemorrhagic E. coli (EHEC) are important, highly virulent zoonotic and food-borne pathogens. The genes encoding their key virulence factors, the Shiga toxins, are distributed by converting bacteriophages, the Stx phages. In this st
- PMID 25445656
Japanese Journal
- クミンの腸管出血性大腸菌O157によるベロ毒素産生の抑制の解析
- 武政 二郎,横井川 久己男
- 日本食品保蔵科学会誌 = Food preservation science 38(4), 217-223, 2012-07-31
- 腸菅出血性大腸菌(EHEC)O157のべロ毒素(VT)産生に対するクミンの抑制能力を調べた。クミン抽出液は70%エチルアルコールを用いて調製した。0.02%クミン抽出液を添加したLB(Luria-Bertani)培地を用いて,37℃で定常期までEHECO157を培養したとき,ベロ毒素生産はVT1とVT2共に有意に低下した。また,この培養条件では,増殖抑制や誘導期の遅延は認められなかった。クミン抽出 …
- NAID 10030964095
- Acid Resistance and Verocytotoxin Productivity of Enterohemorrhagic Escherichia coli O157:H7 Exposed to Microwave
- Tsuji Makiko,Yokoigawa Kumio
- JOURNAL OF FOOD SCIENCE 76(6), M445-M449, 2011
- NAID 120005207151
- Screening and Analysis of Spices with Ability to Suppress Verocytotoxin Production by Escherichia coli O157
Related Links
- verocytotoxin [ver′ō·sī′tō·tok′sin] either of two toxins found in certain strains of Shigella dysenteriae and Escherichia coli, causing a type of hemolytic uremic syndrome. Humans are infected by ingesting undercooked meat ...
- Résultats pour "Verocytotoxin" sur Internet, dans les universités et dans les œuvres littéraires cyclopaedia.net ... Le terme Verocytotoxin est cité dans le Wikipedia de langue anglaise. Il est défini comme suit: Verocytotoxin is a Shiga-like toxin ...
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ベロ毒素
- 関
- shiga toxin、verocytotoxin