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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/11/23 18:21:52」(JST)
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Varicellovirus |
Virus classification |
Group: |
Group I (dsDNA) |
Order: |
Herpesvirales |
Family: |
Herpesviridae |
Subfamily: |
Alphaherpesvirinae |
Genus: |
Varicellovirus |
Type species |
Human herpesvirus 3
|
Varicellovirus (var′i-sel′ō-vi′rŭs) is a genus belonging to subfamily Alphaherpesvirinae, a member of family Herpesviridae.
The varicellovirus genus contains several closely related viruses, including Varicella zoster virus (human herpesvirus 3), the causative agent of chickenpox in humans, and pseudorabies virus (also known as Suid herpesvirus 1), the causative agent of Aujeszky's disease (pseudorabies).
Contents
- 1 Morphology
- 2 Hosts
- 3 Literature
- 4 See also
- 5 External links
Morphology
As with other alphaherpesviruses, the virus particle has a layered structure: Virions consist of an envelope, a tegument, a nucleocapsid, and a core. Tegument is disordered; they do not display a structure and proteins in variable amounts are arranged sometimes in an asymmetric layer located between envelope and capsid. The viral capsid is contained within a spherical envelope which is 120-200 nm in diameter. Surface projections on envelope (viral receptors) are densely dispersed and contain small spikes that evenly dot the surface.
The capsid/nucleocapsid is round and exhibits icosahedral symmetry. The capsid is isometric and has a diameter of 100–110 nm. The capsid consists of 162 capsomer proteins with a hexagonal base and a hole running halfway down the long axis. The core consists of a fibrillar spool on which the DNA is wrapped. The end of the fibers are anchored to the underside of the capsid shell.[1] It is a double-stranded enveloped DNA virus
Hosts
The virus's natural host is a single type of vertebrate host. One member of the Varicellovirus genus, Varicella zoster virus (HHV-3) infects Homo sapiens (humans).[2]
Literature
- ^ ICTVdB—The Universal Virus Database, version 4. http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/
- ^ Davison, A.J. (2002). Evolution of the herpesviruses. Vet. Microbial., 86, 69–88.
See also
- Varicella zoster virus
- Pseudorabies virus
- Simian varicella virus
External links
- Virus Pathogen Database and Analysis Resource (ViPR): Herpesviridae
English Journal
- Differentiation between wild-type and vaccines strains of varicella zoster virus (VZV) based on four single nucleotide polymorphisms.
- Jin L1, Xu S2, Maple PAC1, Xu W2, Brown KE1.
- Epidemiology and infection.Epidemiol Infect.2017 Sep;145(12):2618-2625. doi: 10.1017/S0950268817001509. Epub 2017 Jul 27.
- PMID 28748773
- Cytomegalovirus and varicella zoster virus seropositivity of Iranian patients with multiple sclerosis: A population-based study.
- Karampoor S1, Zahednasab H2, Ramagopalan S3, Mehrpour M4, Etemadifar M5, Alsahebfosoul F6, Keyvani H7.
- Journal of neuroimmunology.J Neuroimmunol.2017 Aug 15;309:4-6. doi: 10.1016/j.jneuroim.2017.04.004. Epub 2017 Apr 8.
- PMID 28601285
- Role of the JNK Pathway in Varicella-Zoster Virus Lytic Infection and Reactivation.
- Kurapati S1, Sadaoka T2,3, Rajbhandari L1, Jagdish B1, Shukla P1, Ali MA2, Kim YJ4, Lee G4,5, Cohen JI2, Venkatesan A6.
- Journal of virology.J Virol.2017 Aug 10;91(17). pii: e00640-17. doi: 10.1128/JVI.00640-17. Print 2017 Sep 1.
- PMID 28637759
Related Links
- Varicellovirus [var″ĭ-sel´o-vi″rus] a genus of herpesviruses that infects both humans and animals; the most common species affecting humans is human herpesvirus 3, which causes chickenpox and herpes zoster. var·i·cel·la-·zos·ter vi ...
- Varicellovirus (var′i-sel′ō-vi′rŭs) is a genus belong to subfamily Alphaherpesvirinae, a member of family Herpesviridae. The varicellovirus genus contains several closely related viruses, including Varicella zoster virus (human herpesvirus ...
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