urinastatin

English Journal

Ulinastatin and/or thymosin α1 for severe sepsis: A systematic review and meta-analysis.

Feng Z1, Shi Q, Fan Y, Wang Q, Yin W.
The journal of trauma and acute care surgery.J Trauma Acute Care Surg.2016 Feb;80(2):335-40. doi: 10.1097/TA.0000000000000909.
OBJECTIVE: Ulinastatin (UTI) and thymosin α1 (Tα1) have been investigated for their immunoregulatory properties in patients with severe sepsis. However, it is unclear whether immunomodulatory therapy using UTI combined with Tα1 (UCT), UTI alone (UA), or Tα1 alone (TA) improves the disease outcom
PMID 26517783

[Protective effect of ulinastatin on cerebral tissue in rats with lethal scald injury].

Liu R1, Wang S, Cao W, Li Z, Zhao Z, Sheng Z, Hu S2.
Zhonghua yi xue za zhi.Zhonghua Yi Xue Za Zhi.2015 Sep 22;95(36):2952-4.
OBJECTIVE: To explore the protective effects of ulinastatin on cerebral tissue in rats following lethal burn injury and its relationship with the expression of protective protein.METHODS: A total of 40 male Sprague-Dawley rats were randomly divided into scald and ulinastatin groups (n = 20 each). Bo
PMID 26814073

Kakizaki I1, Takahashi R2, Yanagisawa M3, Yoshida F3, Takagaki K4.
Carbohydrate research.Carbohydr Res.2015 Sep 2;413:129-34. doi: 10.1016/j.carres.2015.05.009. Epub 2015 Jun 3.
Human urinary trypsin inhibitor is a proteoglycan that has a single low-sulfated chondroitin 4-sulfate chain at the seryl residue in position 10 of the core protein as a glycosaminoglycan moiety, and is used as an anti-inflammatory medicine based on the protease inhibitory activity of the core prote
PMID 26142361

鶴田紀子,桑代麻希,永瀬浩太郎,井上卓也,成澤寛,與田幸恵,能城浩和,中村公秀,坂口嘉郎
日本皮膚アレルギー・接触皮膚炎学会雑誌 11(2), 165-168, 2017
<p>　21歳男性。外科手術の麻酔導入時にアナフィラキシーショックを発症し, 手術が中止された。ロクロニウムの皮内テストが陽性であったため, 筋弛緩薬を用いずに再手術を行ったが, 再びアナフィラキシーショックをきたし中止となった。原因薬を同定するために, ICUでモニタリング下に１剤ずつ投与テストを実施したところ, ウリナスタチンで膨疹, 咳嗽等のアナフィラキシー症状が誘発された。ウリ …
NAID 130006899994

菅野伸洋,湯川寛夫,嶋田裕子,大城久,利野靖,益田宗孝
日本臨床外科学会雑誌 = The journal of the Japan Surgical Association 72(2), 379-383, 2011-02-25
症例は6歳，男児．Henoch-Schönlein紫斑病（HSP）に対し，前医にてステロイドや第XIII因子，ウリナスタチンの投与，ステロイドパルス療法などの対処療法を行ったが，紫斑，腹痛，下血は徐々に増悪した．腎機能障害も出現し，第16病日当院小児科紹介入院となった．再度ステロイドパルス療法，ステロイド投与を行い，症状・検査データーともに一時改善に向かったが，第24病日腹痛再燃，翌日腹 …
NAID 10028121060