同: UDPGT

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1. ビリルビン代謝 bilirubin metabolism
2. インテグラーゼ阻害剤の薬理学 pharmacology of integrase inhibitors
3. 肝細胞移植 hepatocyte transplantation
4. 小児における非抱合型高ビリルビン血症による黄疸の評価 evaluation of jaundice caused by unconjugated hyperbilirubinemia in children
5. HIVプロテアーゼ阻害剤 hiv protease inhibitors

English Journal

[Progress in the study of UDP-glucuronosyltransferase gene polymorphism].

Guo D, Pang LF, Zhou HH.SourceInstitute of Clinical Pharmacology, Xiang-Ya Medical College, Central South University, Changsha 410078, China.
Sheng li ke xue jin zhan [Progress in physiology].Sheng Li Ke Xue Jin Zhan.2010 Apr;41(2):107-11.
Uridinediphosphoglucuronate-glucuronosyltransferase (UGT) is the most important enzyme of the body in phase II metabolism. UGT is widely distributed in multiple tissues, including liver, kidney and intestine, which metabolizes a large number of exogenous toxic substances and endogenous substances. S
PMID 21416995

Long-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposon.

Wang X, Sarkar DP, Mani P, Steer CJ, Chen Y, Guha C, Chandrasekhar V, Chaudhuri A, Roy-Chowdhury N, Kren BT, Roy-Chowdhury J.SourceDepartment of Medicine, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx 10461, NY, USA.
Hepatology (Baltimore, Md.).Hepatology.2009 Sep;50(3):815-24.
Asialoglycoprotein receptor (ASGPR)-mediated endocytosis has been used to target genes to hepatocytes in vivo. However, the level and duration of transgene expression have been low because of lysosomal translocation and degradation of the DNA and lack of its integration into the host genome. In this
PMID 19585550

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