English Journal

Understanding the reaction mechanism and intermediate stabilization in Mammalian serine racemase using multiscale quantum-classical simulations.

Nitoker N1, Major DT.
Biochemistry.Biochemistry.2015 Jan 20;54(2):516-27. doi: 10.1021/bi500984m. Epub 2014 Dec 30.
Serine racemase (SerR) is a pyridoxal-5'-phosphate (PLP)-dependent enzyme catalyzing the racemization of l-Ser to d-Ser. In mammals, d-Ser is an endogenous coagonist required for the activation of N-methyl-d-aspartate receptors (NMDARs), thus making SerR a promising pharmaceutical target. However, m
PMID 25493718

Mooney V1, Sekharan S, Liu J, Guo Y, Batista VS, Yan EC.
Journal of the American Chemical Society.J Am Chem Soc.2015 Jan 14;137(1):307-13. doi: 10.1021/ja510553f. Epub 2014 Dec 26.
Visual pigments can be thermally activated via isomerization of the retinyl chromophore and hydrolysis of the Schiff base (SB) through which the retinyl chromophore is bound to the opsin protein. Here, we present the first combined experimental and theoretical study of the thermal activation of a Si
PMID 25514632

Guo J1, Lyaruu DM1, Takano Y2, Gibson CW3, DenBesten PK4, Bronckers AL5.
Journal of dental research.J Dent Res.2014 Dec 22. pii: 0022034514564186. [Epub ahead of print]
Amelogenins are the most abundant protein species in forming dental enamel, taken to regulate crystal shape and crystal growth. Unprotonated amelogenins can bind protons, suggesting that amelogenins could regulate the pH in enamel in situ. We hypothesized that without amelogenins the enamel would ac
PMID 25535204

Japanese Journal

松田欣之
分光研究 = Journal of the spectroscopical research of Japan 56(2), 55-61, 2007-04-15
… The methods are applied to ammonia clusters and unprotonated ammonia cluster cations. …
NAID 10018417878

山口孝浩,遠藤佑太,小村照寿 [他],高橋光信
電気化学および工業物理化学 : denki kagaku 74(1), 59-64, 2006-01-05
… We postulate that protons transfer from the reduced indigo ion to the unprotonated terminal amino groups of thiols. …
NAID 130001278474

山口孝浩,遠藤佑太,小村照寿,高橋光信
Electrochemistry 74(1), 59-64, 2006
… We postulate that protons transfer from the reduced indigo ion to the unprotonated terminal amino groups of thiols. …
NAID 120005368218