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English Journal

Stability and binding of the phosphorylated species of the N-terminal domain of enzyme I and the histidine phosphocarrier protein from the Streptomyces coelicolor phosphoenolpyruvate:sugar phosphotransferase system.

Doménech R, Martínez-Gómez AI, Aguado-Llera D, Martínez-Rodríguez S, Clemente-Jiménez JM, Velázquez-Campoy A, Neira JL.SourceInstituto de Biología Molecular y Celular, Universidad Miguel Hernández, Elche (Alicante), Spain.
Archives of biochemistry and biophysics.Arch Biochem Biophys.2012 Oct 1;526(1):44-53. Epub 2012 Jul 15.
The phosphotransferase system (PTS) is involved in the use of carbon sources in bacteria. It is formed by two general proteins: enzyme I (EI) and the histidine phosphocarrier (HPr), and various sugar-specific permeases. EI is formed by two domains, with the N-terminal domain (EIN) being responsible
PMID 22809892

Aggregated low-density lipoprotein induce impairment of the cytoskeleton dynamics through urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor in human vascular smooth muscle cell.

Lugano R, Peña E, Badimon L, Padró T.SourceCardiovascular Research Center (CSIC-ICCC), Biomedical Research Institute Sant- Pau (IIB-Sant Pau) CiberOBN, Institute Carlos III Autonomous University of Barcelona, Barcelona, Spain.
Journal of thrombosis and haemostasis : JTH.J Thromb Haemost.2012 Oct;10(10):2158-2167. doi: 10.1111/j.1538-7836.2012.04896.x.
Summary. Background: Urokinase-type plasminogen activator (UPA) regulates vascular smooth muscle cell (VSMC) functions relevant in vascular remodeling by facilitating proteolysis at the cell surface and inducing cell signaling pathways. Our previous results demonstrated that aggregated low-den
PMID 22906080

竹谷浩介
生物物理化学 56(Suppl_1), S15-S19, 2012
… In myosin phosphorylation analysis, it is important to quantify the ratio between phosphorylated and unphosphorylated myosin because those can have opposite effects on contractions. …
NAID 130004809448

田中稔久,丸山大輔,武田雅俊
臨床神経学 52(11), 1171-1173, 2012
… FTDP-17 mutation increased affinity of unphosphorlated tau to 14-3-3, compared to wild typed unphosphorylated tau. …
NAID 130004505095

Effects of Halogenation on Tyrosine Phosphorylation and Peptide Binding to the Src Homology 2 Domain of Lymphocyte-Specific Protein Tyrosine Kinase

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Biological and Pharmaceutical Bulletin 35(3), 433-437, 2012
… The relative affinities of the modified peptides whose phosphotyrosine was substituted with unphosphorylated tyrosine, 3-nitrotyrosine, and 3-iodotyrosine, and of the model peptide were 0.024, 0.26, 1, and 16, respectively. …
NAID 130001872328